STRINGSTRING
AKV57870.1 AKV57870.1 mdh mdh AKV57992.1 AKV57992.1 AKV59760.1 AKV59760.1 AKV58021.1 AKV58021.1 AKV59768.1 AKV59768.1 AKV58029.1 AKV58029.1 AKV59769.1 AKV59769.1 AKV58030.1 AKV58030.1 AKV58031.1 AKV58031.1 AKV58032.1 AKV58032.1 AKV58033.1 AKV58033.1 gcvH gcvH gcvT gcvT AKV59770.1 AKV59770.1 AKV59771.1 AKV59771.1 AKV58114.1 AKV58114.1 AKV58125.1 AKV58125.1 mqo mqo gabD2 gabD2 acnA acnA AKV58388.1 AKV58388.1 AKV58389.1 AKV58389.1 AKV58390.1 AKV58390.1 AKV58391.1 AKV58391.1 ldh ldh kgd kgd AKV58703.1 AKV58703.1 aspA-2 aspA-2 glyA glyA AKV58741.1 AKV58741.1 AKV58757.1 AKV58757.1 AKV59884.1 AKV59884.1 AKV58846.1 AKV58846.1 AKV59910.1 AKV59910.1 AKV58984.1 AKV58984.1 AKV58994.1 AKV58994.1 AKV59001.1 AKV59001.1 AKV59002.1 AKV59002.1 prpB prpB AKV59004.1 AKV59004.1 acpS acpS AKV59012.1 AKV59012.1 AKV59013.1 AKV59013.1 AKV59014.1 AKV59014.1 ppc ppc AKV59074.1 AKV59074.1 AKV59237.1 AKV59237.1 sdhA sdhA AKV59238.1 AKV59238.1 AKV59240.1 AKV59240.1 AKV59308.1 AKV59308.1 AKV59322.1 AKV59322.1 AKV59466.1 AKV59466.1 AKV59467.1 AKV59467.1 AKV59529.1 AKV59529.1 AKV59547.1 AKV59547.1 AKV59548.1 AKV59548.1 pckG pckG AKV59569.1 AKV59569.1 AKV59577.1 AKV59577.1 AKV59600.1 AKV59600.1 AKV59639.1 AKV59639.1 ackA ackA AKV59662.1 AKV59662.1 AKV59723.1 AKV59723.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKV57870.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (331 aa)
AKV57992.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AKV59760.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)
AKV58021.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
AKV59768.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
AKV58029.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AKV59769.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AKV58030.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (509 aa)
AKV58031.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AKV58032.1Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (961 aa)
AKV58033.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (361 aa)
AKV59770.1Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. (947 aa)
AKV59771.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
AKV58114.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
AKV58125.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
gabD2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (938 aa)
AKV58388.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
AKV58389.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
AKV58390.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
AKV58391.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (330 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1243 aa)
AKV58703.1Mercuric reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
aspA-2Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (435 aa)
AKV58741.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
AKV58757.13-hydroxyisobutyryl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AKV59884.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (412 aa)
AKV58846.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (938 aa)
AKV59910.1Diacetyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AKV58984.1Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AKV58994.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
AKV59001.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1142 aa)
AKV59002.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (306 aa)
AKV59004.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (132 aa)
AKV59012.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
AKV59013.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3017 aa)
AKV59014.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (882 aa)
AKV59074.13-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
AKV59237.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (686 aa)
AKV59238.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AKV59240.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
AKV59308.1glutamyl-Q tRNA(Asp) ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (299 aa)
AKV59322.1NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
AKV59466.1Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AKV59467.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AKV59529.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AKV59547.1Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1581 aa)
AKV59548.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (619 aa)
AKV59569.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (515 aa)
AKV59577.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
AKV59600.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (506 aa)
AKV59639.1Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
AKV59662.1Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1297 aa)
AKV59723.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
Your Current Organism:
Corynebacterium riegelii
NCBI taxonomy Id: 156976
Other names: ATCC 700782, C. riegelii, CCUG 38180, CIP 105310, DMMZ 2415, DSM 44326, JCM 10389
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