STRINGSTRING
pstB pstB AKV57830.1 AKV57830.1 crcB crcB AKV57832.1 AKV57832.1 AKV57845.1 AKV57845.1 lepA lepA AKV57912.1 AKV57912.1 AKV57913.1 AKV57913.1 era era AKV57963.1 AKV57963.1 AKV57999.1 AKV57999.1 AKV58027.1 AKV58027.1 AKV58047.1 AKV58047.1 AKV58048.1 AKV58048.1 mraY mraY murG murG AKV59776.1 AKV59776.1 lspA lspA AKV58089.1 AKV58089.1 lgt lgt AKV58130.1 AKV58130.1 ftsY ftsY AKV58193.1 AKV58193.1 AKV58202.1 AKV58202.1 AKV58214.1 AKV58214.1 AKV58215.1 AKV58215.1 secD secD secF secF mltG mltG AKV58300.1 AKV58300.1 AKV58332.1 AKV58332.1 ctaB ctaB AKV58363.1 AKV58363.1 pyrD pyrD uppP uppP tatA tatA tatC tatC lnt lnt secA secA AKV58484.1 AKV58484.1 AKV58486.1 AKV58486.1 AKV59835.1 AKV59835.1 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB AKV58588.1 AKV58588.1 AKV58606.1 AKV58606.1 AKV58657.1 AKV58657.1 AKV59860.1 AKV59860.1 AKV58660.1 AKV58660.1 AKV58661.1 AKV58661.1 AKV59862.1 AKV59862.1 AKV59863.1 AKV59863.1 AKV58692.1 AKV58692.1 AKV58718.1 AKV58718.1 AKV58750.1 AKV58750.1 AKV58761.1 AKV58761.1 AKV58775.1 AKV58775.1 phnC phnC AKV58780.1 AKV58780.1 AKV58791.1 AKV58791.1 mscL mscL AKV58814.1 AKV58814.1 AKV58853.1 AKV58853.1 AKV58854.1 AKV58854.1 AKV58893.1 AKV58893.1 ftsE ftsE AKV58904.1 AKV58904.1 AKV58941.1 AKV58941.1 secA-2 secA-2 AKV59906.1 AKV59906.1 AKV59909.1 AKV59909.1 AKV58979.1 AKV58979.1 AKV58998.1 AKV58998.1 AKV58999.1 AKV58999.1 AKV59010.1 AKV59010.1 metN metN AKV59033.1 AKV59033.1 AKV59046.1 AKV59046.1 AKV59047.1 AKV59047.1 secY secY AKV59116.1 AKV59116.1 secE secE menA menA AKV59318.1 AKV59318.1 AKV59335.1 AKV59335.1 AKV59346.1 AKV59346.1 crgA crgA AKV59393.1 AKV59393.1 AKV59424.1 AKV59424.1 AKV59425.1 AKV59425.1 gltS gltS AKV59458.1 AKV59458.1 AKV59510.1 AKV59510.1 AKV59521.1 AKV59521.1 AKV59522.1 AKV59522.1 AKV59584.1 AKV59584.1 ftsH ftsH AKV59697.1 AKV59697.1 pstC pstC pstA pstA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa)
AKV57830.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (856 aa)
crcBHypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa)
AKV57832.1Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity. (113 aa)
AKV57845.1Cytochrome C oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (584 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (620 aa)
AKV57912.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AKV57913.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (306 aa)
AKV57963.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
AKV57999.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AKV58027.1Amino acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
AKV58047.1Cytochrome C oxidase; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family. (143 aa)
AKV58048.1Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (368 aa)
murGUDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (364 aa)
AKV59776.1Hypothetical protein; Essential cell division protein. (218 aa)
lspAPeptidase A8; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (164 aa)
AKV58089.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
lgtDiacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (293 aa)
AKV58130.1Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (547 aa)
AKV58193.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (993 aa)
AKV58202.1Biotin biosynthesis protein BioY; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AKV58214.1Glutamate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AKV58215.1Glutamate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (599 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (387 aa)
mltGABC transporter substrate-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (382 aa)
AKV58300.1Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (350 aa)
AKV58332.1Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (82 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (300 aa)
AKV58363.1YdjX-Z family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
pyrDDiguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (361 aa)
uppPUDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (275 aa)
tatAProhead protease; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (102 aa)
tatCPreprotein translocase subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (307 aa)
lntAcyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (506 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (763 aa)
AKV58484.1Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AKV58486.1Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AKV59835.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
atpCATP synthase F0F1 subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (125 aa)
atpDATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (463 aa)
atpGATP synthase F0F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (325 aa)
atpAATP synthase F0F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (555 aa)
atpHATP F0F1 synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (277 aa)
atpFATP synthase F0F1 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (193 aa)
atpEATP F0F1 synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa)
atpBATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (264 aa)
AKV58588.1L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (558 aa)
AKV58606.1Proline:sodium symporter PutP; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa)
AKV58657.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
AKV59860.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AKV58660.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AKV58661.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
AKV59862.1Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (487 aa)
AKV59863.1Iron-siderophore ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (351 aa)
AKV58692.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
AKV58718.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (518 aa)
AKV58750.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AKV58761.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (347 aa)
AKV58775.1Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
phnCPhosphonate ABC transporter ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (265 aa)
AKV58780.1Glycine/betaine ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BCCT transporter (TC 2.A.15) family. (584 aa)
AKV58791.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
mscLMechanosensitive ion channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (138 aa)
AKV58814.1Hypothetical protein; Essential cell division protein. (207 aa)
AKV58853.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (340 aa)
AKV58854.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (312 aa)
AKV58893.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
ftsEABC transporter; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
AKV58904.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (320 aa)
AKV58941.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (985 aa)
secA-2Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (863 aa)
AKV59906.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AKV59909.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AKV58979.1Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AKV58998.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (352 aa)
AKV58999.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (354 aa)
AKV59010.1Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
metNMethionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
AKV59033.1Methionine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AKV59046.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AKV59047.1Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (442 aa)
AKV59116.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (109 aa)
menA1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (329 aa)
AKV59318.1Magnesium transporter; Acts as a magnesium transporter. (455 aa)
AKV59335.1Threonine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AKV59346.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
crgASeptation inhibitor protein; Involved in cell division; Belongs to the CrgA family. (91 aa)
AKV59393.1Membrane protein insertion efficiency factor; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (104 aa)
AKV59424.1Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AKV59425.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
gltSSodium:glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. (398 aa)
AKV59458.1MFS transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
AKV59510.1Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
AKV59521.1Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (340 aa)
AKV59522.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (331 aa)
AKV59584.1Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (772 aa)
AKV59697.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
pstCPhosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa)
pstAPhosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
Your Current Organism:
Corynebacterium riegelii
NCBI taxonomy Id: 156976
Other names: ATCC 700782, C. riegelii, CCUG 38180, CIP 105310, DMMZ 2415, DSM 44326, JCM 10389
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