STRINGSTRING
acnA acnA AKV58353.1 AKV58353.1 tal tal zwf zwf pgl pgl tpiA tpiA pgk pgk gap gap AKV58319.1 AKV58319.1 AKV58281.1 AKV58281.1 AKV58247.1 AKV58247.1 mqo mqo AKV58163.1 AKV58163.1 AKV58114.1 AKV58114.1 ilvA ilvA AKV58053.1 AKV58053.1 AKV59771.1 AKV59771.1 AKV59770.1 AKV59770.1 gcvT gcvT gcvH gcvH AKV59760.1 AKV59760.1 eno eno AKV57937.1 AKV57937.1 AKV57915.1 AKV57915.1 mdh mdh AKV59743.1 AKV59743.1 AKV59741.1 AKV59741.1 serB serB glyA glyA prs prs AKV58756.1 AKV58756.1 AKV58774.1 AKV58774.1 pgi pgi AKV59884.1 AKV59884.1 AKV57958.1 AKV57958.1 AKV59012.1 AKV59012.1 AKV59014.1 AKV59014.1 AKV59019.1 AKV59019.1 ppc ppc folD folD AKV59097.1 AKV59097.1 AKV58986.1 AKV58986.1 vapC vapC gpmA gpmA AKV58833.1 AKV58833.1 AKV59237.1 AKV59237.1 sdhA sdhA AKV59238.1 AKV59238.1 AKV59240.1 AKV59240.1 AKV59263.1 AKV59263.1 AKV59286.1 AKV59286.1 AKV59349.1 AKV59349.1 AKV59981.1 AKV59981.1 AKV59529.1 AKV59529.1 AKV59548.1 AKV59548.1 AKV59623.1 AKV59623.1 AKV59639.1 AKV59639.1 ackA ackA AKV59723.1 AKV59723.1 AKV59726.1 AKV59726.1 AKV59727.1 AKV59727.1 AKV58994.1 AKV58994.1 AKV59001.1 AKV59001.1 aspA-2 aspA-2 glpX glpX AKV58703.1 AKV58703.1 AKV58671.1 AKV58671.1 AKV59861.1 AKV59861.1 AKV58670.1 AKV58670.1 kgd kgd pfkA pfkA AKV58520.1 AKV58520.1 AKV58416.1 AKV58416.1 AKV58389.1 AKV58389.1 AKV58385.1 AKV58385.1 fhs fhs
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (938 aa)
AKV58353.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family. (88 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (361 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (517 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (225 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (405 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
AKV58319.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (234 aa)
AKV58281.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (466 aa)
AKV58247.1Polyphosphate glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
AKV58163.1Catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
AKV58114.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (424 aa)
AKV58053.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AKV59771.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
AKV59770.1Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. (947 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (361 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa)
AKV59760.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa)
AKV57937.1Formamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
AKV57915.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (331 aa)
AKV59743.1Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
AKV59741.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
serBPhosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (435 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
AKV58756.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (482 aa)
AKV58774.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (545 aa)
AKV59884.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (412 aa)
AKV57958.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
AKV59012.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
AKV59014.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AKV59019.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (725 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (882 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
AKV59097.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
AKV58986.1acyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
vapCHypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (135 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
AKV58833.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (375 aa)
AKV59237.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (686 aa)
AKV59238.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AKV59240.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
AKV59263.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
AKV59286.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
AKV59349.1Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
AKV59981.1Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (329 aa)
AKV59529.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AKV59548.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
AKV59623.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
AKV59639.1Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
AKV59723.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
AKV59726.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AKV59727.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (313 aa)
AKV58994.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
AKV59001.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1142 aa)
aspA-2Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AKV58703.1Mercuric reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AKV58671.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
AKV59861.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (875 aa)
AKV58670.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1243 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
AKV58520.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (541 aa)
AKV58416.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (490 aa)
AKV58389.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
AKV58385.1Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (551 aa)
Your Current Organism:
Corynebacterium riegelii
NCBI taxonomy Id: 156976
Other names: ATCC 700782, C. riegelii, CCUG 38180, CIP 105310, DMMZ 2415, DSM 44326, JCM 10389
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