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metF metF metE metE AIJ32731.1 AIJ32731.1 metX metX metZ metZ sseA_1 sseA_1 serC serC cysQ cysQ hom hom thrB thrB serA serA sdaB sdaB nrnA nrnA ilvA ilvA AIJ33941.1 AIJ33941.1 patB patB AIJ34064.1 AIJ34064.1 metB metB cysK1 cysK1 cysE cysE sseA_2 sseA_2 cysY cysY cysNC cysNC cysD cysD cysH cysH AIJ34297.1 AIJ34297.1 sir sir fprA fprA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metFMethylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (321 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (754 aa)
AIJ32731.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
metXHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (382 aa)
metZHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
sseA_1Thiosulfate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (375 aa)
cysQMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
homHomoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)
serA3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (527 aa)
sdaBSerine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (465 aa)
nrnAExopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (435 aa)
AIJ33941.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
patBAminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
AIJ34064.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
metBCystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
cysK1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
cysESerine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
sseA_2Sulfultransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
cysYHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
cysNCSulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (429 aa)
cysDSulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (260 aa)
AIJ34297.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
sirSulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (557 aa)
fprAPyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
Your Current Organism:
Corynebacterium imitans
NCBI taxonomy Id: 156978
Other names: ATCC 700354, C. imitans, CCUG 36877, CIP 105130, Corynebacterium sp. 2023, DSM 44264, IFO 16163, JCM 10386, NBRC 100416, NBRC 16163, NCTC 13015
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