STRINGSTRING
sdhC sdhC sdhA sdhA frdB frdB alsD alsD gabD1_1 gabD1_1 caiD caiD gabD2_1 gabD2_1 ilvB ilvB ilvH ilvH pflAC pflAC pflB pflB gabD2 gabD2 AIJ33965.1 AIJ33965.1 scpC scpC scoB scoB scoA scoA thlA thlA mhpF mhpF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa)
frdBSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
alsDAlpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. (250 aa)
gabD1_1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
caiD3-hydroxyisobutyryl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
gabD2_1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (489 aa)
ilvBAcetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
ilvHAcetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
pflACFormate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
pflBFormate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa)
gabD2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
AIJ33965.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
scpCacetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
scoBsuccinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
scoALipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
thlAacetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
mhpFAcetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (319 aa)
Your Current Organism:
Corynebacterium imitans
NCBI taxonomy Id: 156978
Other names: ATCC 700354, C. imitans, CCUG 36877, CIP 105130, Corynebacterium sp. 2023, DSM 44264, IFO 16163, JCM 10386, NBRC 100416, NBRC 16163, NCTC 13015
Server load: low (20%) [HD]