(66 nodes) EPH-Ephrin signaling network (Trichobilharzia regenti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRE_LOCUS16462	Uncharacterized protein. (90 aa)
	TRE_LOCUS14448	Uncharacterized protein. (423 aa)
	TRE_LOCUS14064	CRIB domain-containing protein. (96 aa)
	TRE_LOCUS13499	Uncharacterized protein. (226 aa)
	A0A183WMS1	Uncharacterized protein. (82 aa)
	TRE_LOCUS13036	Protein kinase domain-containing protein. (90 aa)
	TRE_LOCUS12628	Uncharacterized protein. (222 aa)
	TRE_LOCUS12273	Uncharacterized protein. (173 aa)
	TRE_LOCUS11709	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
	TRE_LOCUS11369	Uncharacterized protein. (121 aa)
	TRE_LOCUS11274	Uncharacterized protein. (146 aa)
	TRE_LOCUS11096	Uncharacterized protein. (167 aa)
	TRE_LOCUS10889	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (121 aa)
	TRE_LOCUS10341	Protein kinase domain-containing protein. (112 aa)
	TRE_LOCUS10239	Uncharacterized protein. (154 aa)
	TRE_LOCUS10063	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (121 aa)
	A0A183WCZ0	WD_REPEATS_REGION domain-containing protein. (353 aa)
	A0A183WCX4	Protein kinase domain-containing protein. (168 aa)
	TRE_LOCUS9754	Uncharacterized protein; Belongs to the actin family. (177 aa)
	TRE_LOCUS8244	Uncharacterized protein. (277 aa)
	A0A183W7K9	Uncharacterized protein. (289 aa)
	TRE_LOCUS19842	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (151 aa)
	TRE_LOCUS20142	Uncharacterized protein. (107 aa)
	A0A183X736	Uncharacterized protein. (91 aa)
	A0A183X8M9	4.1m domain-containing protein. (47 aa)
	A0A183XA36	Uncharacterized protein. (150 aa)
	TRE_LOCUS5684	ANF_receptor domain-containing protein. (146 aa)
	TRE_LOCUS6170	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (156 aa)
	TRE_LOCUS6387	Protein kinase domain-containing protein. (323 aa)
	TRE_LOCUS6661	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
	TRE_LOCUS6948	Uncharacterized protein. (414 aa)
	A0A183W571	Uncharacterized protein. (139 aa)
	A0A183W5B1	Uncharacterized protein. (293 aa)
	TRE_LOCUS21950	Protein kinase domain-containing protein. (113 aa)
	TRE_LOCUS7582	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (139 aa)
	A0A183W6M2	Uncharacterized protein. (133 aa)
	TRE_LOCUS22131	PDZ domain-containing protein. (56 aa)
	A0A183WWK1	Ncstrn_small domain-containing protein. (266 aa)
	A0A183WV74	Uncharacterized protein. (62 aa)
	A0A183X4H1	Uncharacterized protein. (79 aa)
	A0A183X3Y4	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (74 aa)
	TRE_LOCUS19010	Uncharacterized protein. (96 aa)
	TRE_LOCUS18601	Uncharacterized protein. (174 aa)
	TRE_LOCUS18392	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (127 aa)
	TRE_LOCUS18209	Uncharacterized protein. (102 aa)
	TRE_LOCUS18189	Uncharacterized protein. (75 aa)
	A0A183X054	Uncharacterized protein. (335 aa)
	TRE_LOCUS17736	Pkinase_Tyr domain-containing protein. (308 aa)
	A0A183WZD4	Uncharacterized protein. (101 aa)
	A0A183WYZ1	Uncharacterized protein. (245 aa)
	A0A183WYJ5	Uncharacterized protein. (89 aa)
	TRE_LOCUS16915	Uncharacterized protein. (141 aa)
	A0A183WXA3	Protein kinase domain-containing protein. (86 aa)
	TRE_LOCUS16750	Uncharacterized protein. (114 aa)
	A0A183VIE7	Uncharacterized protein. (101 aa)
	A0A183VL72	Uncharacterized protein. (184 aa)
	TRE_LOCUS764	Uncharacterized protein. (69 aa)
	TRE_LOCUS1952	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (370 aa)
	TRE_LOCUS2343	Uncharacterized protein. (764 aa)
	A0A183VQI7	Protein kinase domain-containing protein. (153 aa)
	TRE_LOCUS3189	CRIB domain-containing protein. (361 aa)
	TRE_LOCUS3864	Protein kinase domain-containing protein. (157 aa)
	TRE_LOCUS4135	Uncharacterized protein. (221 aa)
	A0A183VUR1	Uncharacterized protein. (339 aa)
	TRE_LOCUS4273	Uncharacterized protein. (327 aa)
	A0A183VVJ8	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (84 aa)

Your Current Organism:

Trichobilharzia regenti

NCBI taxonomy Id: 157069
Other names: T. regenti, bird nasal schistosome

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A183VL72	A0A183VQI7	A0A183VL72	A0A183VQI7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.567
A0A183VL72	A0A183W571	A0A183VL72	A0A183W571	Uncharacterized protein.	Uncharacterized protein.	0.619
A0A183VL72	A0A183W6M2	A0A183VL72	A0A183W6M2	Uncharacterized protein.	Uncharacterized protein.	0.614
A0A183VL72	A0A183W7K9	A0A183VL72	A0A183W7K9	Uncharacterized protein.	Uncharacterized protein.	0.676
A0A183VL72	A0A183WCX4	A0A183VL72	A0A183WCX4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.567
A0A183VL72	A0A183WMS1	A0A183VL72	A0A183WMS1	Uncharacterized protein.	Uncharacterized protein.	0.676
A0A183VL72	A0A183WWK1	A0A183VL72	A0A183WWK1	Uncharacterized protein.	Ncstrn_small domain-containing protein.	0.668
A0A183VL72	A0A183WYJ5	A0A183VL72	A0A183WYJ5	Uncharacterized protein.	Uncharacterized protein.	0.634
A0A183VL72	A0A183WZD4	A0A183VL72	A0A183WZD4	Uncharacterized protein.	Uncharacterized protein.	0.676
A0A183VL72	A0A183X4H1	A0A183VL72	A0A183X4H1	Uncharacterized protein.	Uncharacterized protein.	0.567
A0A183VL72	A0A183X736	A0A183VL72	A0A183X736	Uncharacterized protein.	Uncharacterized protein.	0.548
A0A183VL72	A0A183XA36	A0A183VL72	A0A183XA36	Uncharacterized protein.	Uncharacterized protein.	0.676
A0A183VL72	TRE_LOCUS10063	A0A183VL72	A0A183WD59	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.561
A0A183VL72	TRE_LOCUS10341	A0A183VL72	A0A183WDY8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.567
A0A183VL72	TRE_LOCUS11096	A0A183VL72	A0A183WG42	Uncharacterized protein.	Uncharacterized protein.	0.619
A0A183VL72	TRE_LOCUS12273	A0A183VL72	A0A183WJH0	Uncharacterized protein.	Uncharacterized protein.	0.614
A0A183VL72	TRE_LOCUS12628	A0A183VL72	A0A183WKH6	Uncharacterized protein.	Uncharacterized protein.	0.567
A0A183VL72	TRE_LOCUS13036	A0A183VL72	A0A183WLN1	Uncharacterized protein.	Protein kinase domain-containing protein.	0.567
A0A183VL72	TRE_LOCUS13499	A0A183VL72	A0A183WMZ6	Uncharacterized protein.	Uncharacterized protein.	0.548
A0A183VL72	TRE_LOCUS14064	A0A183VL72	A0A183WPL1	Uncharacterized protein.	CRIB domain-containing protein.	0.678