(110 nodes) Death Receptor Signaling network (Trichobilharzia regenti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRE_LOCUS21616	Uncharacterized protein. (56 aa)
	TRE_LOCUS944	Uncharacterized protein. (167 aa)
	TRE_LOCUS1072	Uncharacterized protein. (80 aa)
	A0A183VID0	Uncharacterized protein. (101 aa)
	TRE_LOCUS13101	Uncharacterized protein. (138 aa)
	TRE_LOCUS13333	Ubiquitin-like domain-containing protein. (142 aa)
	A0A183WMQ9	Uncharacterized protein. (198 aa)
	TRE_LOCUS13499	Uncharacterized protein. (226 aa)
	A0A183WP57	Uncharacterized protein. (398 aa)
	A0A183WP86	Uncharacterized protein. (145 aa)
	TRE_LOCUS14082	Uncharacterized protein. (332 aa)
	A0A183WQI4	Uncharacterized protein. (178 aa)
	A0A183WQR0	Uncharacterized protein. (194 aa)
	TRE_LOCUS14604	Uncharacterized protein. (59 aa)
	TRE_LOCUS14636	Uncharacterized protein. (86 aa)
	A0A183WRA8	Uncharacterized protein. (151 aa)
	TRE_LOCUS14715	Uncharacterized protein. (214 aa)
	TRE_LOCUS14986	DH domain-containing protein. (174 aa)
	TRE_LOCUS15039	Uncharacterized protein. (119 aa)
	A0A183WSV4	DH domain-containing protein. (144 aa)
	A0A183WSX4	Uncharacterized protein. (266 aa)
	TRE_LOCUS15894	Uncharacterized protein. (101 aa)
	TRE_LOCUS16014	DH domain-containing protein. (343 aa)
	TRE_LOCUS16253	Uncharacterized protein. (492 aa)
	A0A183WWD1	PH domain-containing protein. (245 aa)
	A0A183WWK1	Ncstrn_small domain-containing protein. (266 aa)
	A0A183WX21	Uncharacterized protein. (83 aa)
	A0A183WX92	Uncharacterized protein. (45 aa)
	TRE_LOCUS16750	Uncharacterized protein. (114 aa)
	A0A183WXR4	Uncharacterized protein. (211 aa)
	A0A183WYJ5	Uncharacterized protein. (89 aa)
	TRE_LOCUS17574	DH domain-containing protein. (81 aa)
	A0A183WZN5	Uncharacterized protein. (165 aa)
	TRE_LOCUS17739	Uncharacterized protein. (82 aa)
	TRE_LOCUS18189	Uncharacterized protein. (75 aa)
	TRE_LOCUS18232	RING-type domain-containing protein. (359 aa)
	TRE_LOCUS18623	Uncharacterized protein. (80 aa)
	A0A183X328	CAP-Gly domain-containing protein. (87 aa)
	TRE_LOCUS19010	Uncharacterized protein. (96 aa)
	TRE_LOCUS19728	Uncharacterized protein. (81 aa)
	TRE_LOCUS19726	Ubiquitin-like domain-containing protein. (140 aa)
	TRE_LOCUS19842	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (151 aa)
	A0A183X736	Uncharacterized protein. (91 aa)
	TRE_LOCUS20230	Uncharacterized protein. (167 aa)
	TRE_LOCUS20294	KxDL domain-containing protein. (147 aa)
	A0A183X809	Uncharacterized protein. (83 aa)
	TRE_LOCUS21566	Uncharacterized protein. (213 aa)
	TRE_LOCUS121	Uncharacterized protein. (226 aa)
	TRE_LOCUS193	UDENN domain-containing protein. (206 aa)
	A0A183VJL2	DH domain-containing protein. (399 aa)
	TRE_LOCUS237	DH domain-containing protein. (307 aa)
	A0A183VJX1	N-terminal Ras-GEF domain-containing protein. (153 aa)
	A0A183VK26	Uncharacterized protein. (119 aa)
	A0A183VKX4	Uncharacterized protein. (179 aa)
	TRE_LOCUS723	Uncharacterized protein. (204 aa)
	TRE_LOCUS764	Uncharacterized protein. (69 aa)
	TRE_LOCUS1423	Uncharacterized protein. (656 aa)
	A0A183VMS5	Uncharacterized protein. (163 aa)
	TRE_LOCUS2103	Uncharacterized protein. (268 aa)
	TRE_LOCUS2280	Uncharacterized protein. (300 aa)
	TRE_LOCUS2281	Uncharacterized protein. (174 aa)
	TRE_LOCUS2312	Uncharacterized protein. (203 aa)
	TRE_LOCUS2558	Uncharacterized protein. (635 aa)
	TRE_LOCUS2986	Uncharacterized protein. (343 aa)
	A0A183VRD9	Uncharacterized protein; Belongs to the peptidase C14A family. (606 aa)
	TRE_LOCUS5096	Ras-GEF domain-containing protein. (642 aa)
	A0A183VY05	Uncharacterized protein. (152 aa)
	TRE_LOCUS5978	Uncharacterized protein. (177 aa)
	TRE_LOCUS6090	Uncharacterized protein. (345 aa)
	A0A183W132	RGS-like domain-containing protein. (112 aa)
	TRE_LOCUS6689	UDENN domain-containing protein. (226 aa)
	A0A183W297	Uncharacterized protein. (445 aa)
	TRE_LOCUS6959	Uncharacterized protein. (347 aa)
	TRE_LOCUS6963	Protein kinase domain-containing protein. (247 aa)
	TRE_LOCUS21698	Uncharacterized protein. (71 aa)
	A0A183W3B5	Uncharacterized protein. (604 aa)
	A0A183W3C9	Disintegrin domain-containing protein. (88 aa)
	A0A183W438	Uncharacterized protein. (56 aa)
	TRE_LOCUS7264	Uncharacterized protein. (198 aa)
	A0A183W571	Uncharacterized protein. (139 aa)
	TRE_LOCUS22041	Protein kinase domain-containing protein. (49 aa)
	A0A183W6Q9	DH domain-containing protein. (297 aa)
	TRE_LOCUS8164	ANK_REP_REGION domain-containing protein. (152 aa)
	TRE_LOCUS8170	Uncharacterized protein. (309 aa)
	A0A183W8K9	Uncharacterized protein. (285 aa)
	TRE_LOCUS8473	Uncharacterized protein. (152 aa)
	TRE_LOCUS8690	Uncharacterized protein. (245 aa)
	TRE_LOCUS8901	Uncharacterized protein. (328 aa)
	TRE_LOCUS9530	Uncharacterized protein. (131 aa)
	TRE_LOCUS9698	Uncharacterized protein. (278 aa)
	TRE_LOCUS9845	Uncharacterized protein. (502 aa)
	TRE_LOCUS10059	UCH domain-containing protein. (68 aa)
	TRE_LOCUS10252	Calponin-homology (CH) domain-containing protein. (296 aa)
	A0A183WE09	Uncharacterized protein. (171 aa)
	TRE_LOCUS10600	WD_REPEATS_REGION domain-containing protein. (319 aa)
	TRE_LOCUS10664	BAG domain-containing protein. (196 aa)
	TRE_LOCUS10888	Uncharacterized protein. (116 aa)
	TRE_LOCUS10975	Uncharacterized protein. (146 aa)
	A0A183WFW5	Uncharacterized protein. (245 aa)
	TRE_LOCUS11070	Uncharacterized protein. (123 aa)
	TRE_LOCUS11096	Uncharacterized protein. (167 aa)
	TRE_LOCUS11165	SH2 domain-containing protein. (254 aa)
	TRE_LOCUS11220	MIB/HERC2 domain-containing protein. (116 aa)
	TRE_LOCUS11415	Uncharacterized protein. (852 aa)
	TRE_LOCUS11746	DENN domain-containing protein. (102 aa)
	TRE_LOCUS12128	SH3 domain-containing protein. (113 aa)
	TRE_LOCUS12306	Uncharacterized protein. (191 aa)
	TRE_LOCUS12327	USP domain-containing protein; Belongs to the peptidase C19 family. (232 aa)
	TRE_LOCUS12913	TNFR_16_TM domain-containing protein. (171 aa)
	A0A183WLC3	DH domain-containing protein. (156 aa)

Your Current Organism:

Trichobilharzia regenti

NCBI taxonomy Id: 157069
Other names: T. regenti, bird nasal schistosome

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A183VJL2	A0A183W132	A0A183VJL2	A0A183W132	DH domain-containing protein.	RGS-like domain-containing protein.	0.580
A0A183VJL2	A0A183WQI4	A0A183VJL2	A0A183WQI4	DH domain-containing protein.	Uncharacterized protein.	0.476
A0A183VJL2	TRE_LOCUS10888	A0A183VJL2	A0A183WFI4	DH domain-containing protein.	Uncharacterized protein.	0.580
A0A183VJL2	TRE_LOCUS14636	A0A183VJL2	A0A183WR83	DH domain-containing protein.	Uncharacterized protein.	0.476
A0A183VJL2	TRE_LOCUS2103	A0A183VJL2	A0A183VNP7	DH domain-containing protein.	Uncharacterized protein.	0.580
A0A183VJL2	TRE_LOCUS2280	A0A183VJL2	A0A183VP74	DH domain-containing protein.	Uncharacterized protein.	0.580
A0A183VJL2	TRE_LOCUS2312	A0A183VJL2	A0A183VPA6	DH domain-containing protein.	Uncharacterized protein.	0.580
A0A183VJL2	TRE_LOCUS9845	A0A183VJL2	A0A183WCJ2	DH domain-containing protein.	Uncharacterized protein.	0.580
A0A183VJX1	A0A183VY05	A0A183VJX1	A0A183VY05	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.621
A0A183VJX1	A0A183W132	A0A183VJX1	A0A183W132	N-terminal Ras-GEF domain-containing protein.	RGS-like domain-containing protein.	0.499
A0A183VJX1	A0A183W571	A0A183VJX1	A0A183W571	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.456
A0A183VJX1	A0A183WZN5	A0A183VJX1	A0A183WZN5	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.621
A0A183VJX1	TRE_LOCUS10252	A0A183VJX1	A0A183WDQ0	N-terminal Ras-GEF domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.621
A0A183VJX1	TRE_LOCUS10888	A0A183VJX1	A0A183WFI4	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.499
A0A183VJX1	TRE_LOCUS11096	A0A183VJX1	A0A183WG42	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.456
A0A183VJX1	TRE_LOCUS11165	A0A183VJX1	A0A183WGB1	N-terminal Ras-GEF domain-containing protein.	SH2 domain-containing protein.	0.621
A0A183VJX1	TRE_LOCUS12128	A0A183VJX1	A0A183WJ25	N-terminal Ras-GEF domain-containing protein.	SH3 domain-containing protein.	0.621
A0A183VJX1	TRE_LOCUS1423	A0A183VJX1	A0A183VLR7	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.401
A0A183VJX1	TRE_LOCUS2280	A0A183VJX1	A0A183VP74	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.499
A0A183VJX1	TRE_LOCUS2312	A0A183VJX1	A0A183VPA6	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.499