STRINGSTRING
rnj rnj APE07992.1 APE07992.1 xseB xseB xseA xseA sbcD sbcD recC recC recB recB recD recD APE12037.1 APE12037.1 rph rph orn orn APE08716.1 APE08716.1 APE08908.1 APE08908.1 APE09274.1 APE09274.1 APE09290.1 APE09290.1 polA polA APE09543.1 APE09543.1 APE12192.1 APE12192.1 APE12193.1 APE12193.1 APE09669.1 APE09669.1 APE09721.1 APE09721.1 APE09907.1 APE09907.1 APE12228.1 APE12228.1 APE12249.1 APE12249.1 dnaE2 dnaE2 APE10041.1 APE10041.1 APE10364.1 APE10364.1 APE10730.1 APE10730.1 APE10733.1 APE10733.1 APE10786.1 APE10786.1 APE11039.1 APE11039.1 APE11095.1 APE11095.1 APE11220.1 APE11220.1 APE11469.1 APE11469.1 APE11703.1 APE11703.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rnjRibonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (601 aa)
APE07992.1ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (87 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (421 aa)
sbcDExonuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (392 aa)
recCExodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1097 aa)
recBAAA family ATPase; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme de [...] (1110 aa)
recDExodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (625 aa)
APE12037.13'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (262 aa)
ornOligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (199 aa)
APE08716.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
APE08908.1Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
APE09274.1Recombinase RecB; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APE09290.1Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (907 aa)
APE09543.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1178 aa)
APE12192.1Hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. (163 aa)
APE12193.1Hypothetical protein; Contains 3'-5'exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
APE09669.1MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
APE09721.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
APE09907.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1118 aa)
APE12228.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1108 aa)
APE12249.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1083 aa)
APE10041.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
APE10364.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
APE10730.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
APE10733.1DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
APE10786.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (258 aa)
APE11039.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (259 aa)
APE11095.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (259 aa)
APE11220.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (394 aa)
APE11469.1Bifunctional 3'-5' exonuclease/DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
APE11703.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
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