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acsA acsA APE11300.1 APE11300.1 APE11852.1 APE11852.1 prpE prpE sucC sucC sucD sucD APE08332.1 APE08332.1 APE08374.1 APE08374.1 APE08375.1 APE08375.1 APE08486.1 APE08486.1 APE08793.1 APE08793.1 APE09878.1 APE09878.1 APE09902.1 APE09902.1 APE09920.1 APE09920.1 APE10130.1 APE10130.1 APE11904.1 APE11904.1 APE10809.1 APE10809.1 APE11816.1 APE11816.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (643 aa)
APE11300.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
APE11852.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
APE08332.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)
APE08374.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
APE08375.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
APE08486.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
APE08793.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
APE09878.1acyl--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
APE09902.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
APE09920.1Adenylyltransferase/sulfurtransferase MoeZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
APE10130.1acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
APE11904.1(2,3-dihydroxybenzoyl)adenylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
APE10809.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)
APE11816.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
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