STRINGSTRING
APE10370.1 APE10370.1 APE12486.1 APE12486.1 acsA acsA APE11658.1 APE11658.1 APE11624.1 APE11624.1 dnaX dnaX thiM thiM APE12466.1 APE12466.1 tgt tgt APE12458.1 APE12458.1 APE11572.1 APE11572.1 APE11553.1 APE11553.1 thiC thiC APE11469.1 APE11469.1 APE11466.1 APE11466.1 BO226_21450 BO226_21450 APE11408.1 APE11408.1 APE11379.1 APE11379.1 APE11291.1 APE11291.1 APE11256.1 APE11256.1 APE11238.1 APE11238.1 APE11220.1 APE11220.1 APE12421.1 APE12421.1 APE12419.1 APE12419.1 APE11144.1 APE11144.1 APE11128.1 APE11128.1 trpF trpF APE10939.1 APE10939.1 APE10908.1 APE10908.1 pheA pheA APE10874.1 APE10874.1 serS serS APE10828.1 APE10828.1 APE10730.1 APE10730.1 APE10693.1 APE10693.1 APE10658.1 APE10658.1 APE10648.1 APE10648.1 APE10638.1 APE10638.1 aroD aroD dcd dcd APE10573.1 APE10573.1 APE12323.1 APE12323.1 APE10545.1 APE10545.1 APE10445.1 APE10445.1 pyrE pyrE cobQ cobQ APE10426.1 APE10426.1 cobD cobD APE10422.1 APE10422.1 APE10421.1 APE10421.1 APE10420.1 APE10420.1 APE10419.1 APE10419.1 APE10418.1 APE10418.1 cobH cobH APE12301.1 APE12301.1 APE10416.1 APE10416.1 purA purA APE10380.1 APE10380.1 APE12296.1 APE12296.1 ackA ackA thiE thiE APE10369.1 APE10369.1 thiG thiG APE10366.1 APE10366.1 APE10335.1 APE10335.1 aroE aroE aroQ aroQ APE10307.1 APE10307.1 purU purU hemA hemA hemC hemC APE10238.1 APE10238.1 APE12277.1 APE12277.1 hemL hemL nusG nusG rpoB rpoB rpoC rpoC APE10130.1 APE10130.1 adk adk rpoA rpoA APE10056.1 APE10056.1 guaB guaB APE10052.1 APE10052.1 guaA guaA dnaE2 dnaE2 folD folD add add upp upp purK purK purE purE APE09959.1 APE09959.1 APE09949.1 APE09949.1 tmk tmk aroA aroA APE12232.1 APE12232.1 APE09915.1 APE09915.1 APE09914.1 APE09914.1 APE09873.1 APE09873.1 nadE nadE APE09852.1 APE09852.1 APE09840.1 APE09840.1 nadD nadD APE09783.1 APE09783.1 APE09769.1 APE09769.1 APE12206.1 APE12206.1 dnaG dnaG APE09676.1 APE09676.1 cobS cobS cobT cobT trpD trpD APE12193.1 APE12193.1 APE09576.1 APE09576.1 dinB dinB APE09543.1 APE09543.1 APE09518.1 APE09518.1 nadA nadA APE09507.1 APE09507.1 APE09506.1 APE09506.1 hisA hisA trpE trpE trpC trpC trpB trpB trpA trpA APE09455.1 APE09455.1 polA polA coaE coaE BO226_09605 BO226_09605 nadK nadK APE09391.1 APE09391.1 APE09389.1 APE09389.1 cmk cmk APE09378.1 APE09378.1 APE09363.1 APE09363.1 APE09327.1 APE09327.1 APE09326.1 APE09326.1 APE09325.1 APE09325.1 APE09250.1 APE09250.1 BO226_08365 BO226_08365 APE09207.1 APE09207.1 APE09206.1 APE09206.1 APE09165.1 APE09165.1 APE09160.1 APE09160.1 APE09154.1 APE09154.1 APE09127.1 APE09127.1 pyrD pyrD hemH hemH APE09018.1 APE09018.1 APE09017.1 APE09017.1 ctaB ctaB APE09007.1 APE09007.1 APE08991.1 APE08991.1 priA priA APE08979.1 APE08979.1 rpoZ rpoZ gmk gmk pyrF pyrF carB carB carA carA APE08972.1 APE08972.1 pyrC pyrC pyrB pyrB nusB nusB aroB aroB aroK aroK aroC aroC APE08959.1 APE08959.1 APE08956.1 APE08956.1 APE08947.1 APE08947.1 APE08932.1 APE08932.1 apt apt pdxT pdxT pdxS pdxS APE12099.1 APE12099.1 APE08910.1 APE08910.1 hemE hemE dxs dxs dut dut sigA sigA APE08881.1 APE08881.1 thyX thyX APE08818.1 APE08818.1 APE12082.1 APE12082.1 nusA nusA APE08800.1 APE08800.1 APE08793.1 APE08793.1 pyrH pyrH coaD coaD thiL thiL APE08716.1 APE08716.1 lig lig ndk ndk APE08707.1 APE08707.1 APE08704.1 APE08704.1 selA selA APE08578.1 APE08578.1 APE08577.1 APE08577.1 APE08566.1 APE08566.1 APE08564.1 APE08564.1 murA murA APE08558.1 APE08558.1 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB rho rho APE08515.1 APE08515.1 APE12052.1 APE12052.1 APE08452.1 APE08452.1 APE08351.1 APE08351.1 APE08334.1 APE08334.1 APE08324.1 APE08324.1 APE08287.1 APE08287.1 APE08280.1 APE08280.1 APE08274.1 APE08274.1 APE08263.1 APE08263.1 coaA coaA APE08124.1 APE08124.1 BO226_01815 BO226_01815 glmU glmU prs prs APE08098.1 APE08098.1 APE08080.1 APE08080.1 APE08079.1 APE08079.1 APE08067.1 APE08067.1 APE08049.1 APE08049.1 purH purH APE11983.1 APE11983.1 APE08019.1 APE08019.1 thyA thyA APE07992.1 APE07992.1 APE11972.1 APE11972.1 prpE prpE APE07926.1 APE07926.1 pdxH pdxH serC serC APE11958.1 APE11958.1 APE07875.1 APE07875.1 APE07869.1 APE07869.1 APE07847.1 APE07847.1 APE07844.1 APE07844.1 APE07840.1 APE07840.1 APE11944.1 APE11944.1 purM purM purF purF purL purL purQ purQ purS purS purC purC APE11891.1 APE11891.1 purD purD APE11885.1 APE11885.1 APE11841.1 APE11841.1 APE11747.1 APE11747.1 dinB-2 dinB-2 coaX coaX APE11721.1 APE11721.1 APE11720.1 APE11720.1 APE11719.1 APE11719.1 folE folE APE11716.1 APE11716.1 APE11703.1 APE11703.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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APE10370.1Glycine oxidase ThiO; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
APE12486.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (643 aa)
APE11658.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
APE11624.1CDP-alcohol phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (758 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (281 aa)
APE12466.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (243 aa)
tgttRNA-guanine(34) transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form [...] (414 aa)
APE12458.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
APE11572.1Flavodoxin/nitric oxide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
APE11553.1Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (594 aa)
APE11469.1Bifunctional 3'-5' exonuclease/DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
APE11466.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)
BO226_21450Cytochrome; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
APE11408.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APE11379.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
APE11291.1RNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
APE11256.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
APE11238.1Ribonucleotide-diphosphate reductase subunit beta; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
APE11220.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (394 aa)
APE12421.1RNA polymerase sigma factor SigM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (182 aa)
APE12419.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (202 aa)
APE11144.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
APE11128.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (1035 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (201 aa)
APE10939.1Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
APE10908.1Carbamoyl-phosphate-synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1060 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
APE10874.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa)
APE10828.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (200 aa)
APE10730.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
APE10693.1DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (339 aa)
APE10658.1Cobalamin biosynthesis protein CbiM; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
APE10648.1Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
APE10638.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (256 aa)
dcddCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (196 aa)
APE10573.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (78 aa)
APE12323.1Aspartate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
APE10545.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
APE10445.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (179 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (492 aa)
APE10426.1precorrin-6A reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (305 aa)
APE10422.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
APE10421.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
APE10420.1Cobalamin biosynthesis bifunctional protein CbiET; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
APE10419.1Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
APE10418.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
cobHCatalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
APE12301.1Cobaltochelatase subunit CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. (1203 aa)
APE10416.1precorrin-6A synthase (deacetylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
APE10380.1Adenosylcobinamide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
APE12296.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (694 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (229 aa)
APE10369.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (261 aa)
APE10366.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
APE10335.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
aroQType II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa)
APE10307.1RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (260 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (295 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (473 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (336 aa)
APE10238.1Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
APE12277.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (325 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
nusGTranscription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (278 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1168 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1323 aa)
APE10130.1acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (181 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (353 aa)
APE10056.1RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (507 aa)
APE10052.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1083 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
addAdenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (361 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (424 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (157 aa)
APE09959.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (289 aa)
APE09949.1Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (221 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa)
APE12232.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (212 aa)
APE09915.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
APE09914.1Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
APE09873.1Cobalamin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (278 aa)
APE09852.1Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (333 aa)
APE09840.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa)
APE09783.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
APE09769.1Sirohydrochlorin chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
APE12206.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (415 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (631 aa)
APE09676.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (254 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (363 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (359 aa)
APE12193.1Hypothetical protein; Contains 3'-5'exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
APE09576.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (436 aa)
APE09543.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1178 aa)
APE09518.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (343 aa)
APE09507.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (523 aa)
APE09506.1Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (288 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (531 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (269 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
APE09455.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (907 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (402 aa)
BO226_09605DNA-binding response regulator; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (314 aa)
APE09391.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
APE09389.1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (543 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
APE09378.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
APE09363.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
APE09327.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
APE09326.1Aminodeoxychorismate synthase, component I; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
APE09325.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
APE09250.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (412 aa)
BO226_08365Transposase; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
APE09207.1Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
APE09206.1Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (427 aa)
APE09165.1Cobalamin biosynthesis protein CbiM; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
APE09160.1RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
APE09154.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
APE09127.1Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (356 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (358 aa)
APE09018.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
APE09017.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (325 aa)
APE09007.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (416 aa)
APE08991.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
priAPrimosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (672 aa)
APE08979.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (427 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (100 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (183 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (280 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1114 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (394 aa)
APE08972.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (437 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (313 aa)
nusBN utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (169 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (188 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa)
APE08959.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (415 aa)
APE08956.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (284 aa)
APE08947.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
APE08932.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (770 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (185 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (212 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (301 aa)
APE12099.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
APE08910.1Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (365 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (156 aa)
sigARNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (457 aa)
APE08881.1RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (320 aa)
thyXFAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (251 aa)
APE08818.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (300 aa)
APE12082.14'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily. (220 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (342 aa)
APE08800.1uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
APE08793.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (323 aa)
APE08716.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ligATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
APE08707.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
APE08704.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (434 aa)
APE08578.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (443 aa)
APE08577.1Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
APE08566.1ATP/GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
APE08564.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (426 aa)
APE08558.1ATP:cob(I)alamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (119 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (482 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (327 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (547 aa)
atpHF0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (271 aa)
atpFF0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (187 aa)
atpEATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (82 aa)
atpBATP synthase F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (232 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (654 aa)
APE08515.1Shikimate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
APE12052.1Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
APE08452.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
APE08351.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
APE08334.1TrpB-like pyridoxal-phosphate dependent enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa)
APE08324.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
APE08287.1RNA polymerase sigma factor SigE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (207 aa)
APE08280.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (306 aa)
APE08274.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
APE08263.14a-hydroxytetrahydrobiopterin dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
APE08124.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
BO226_01815Nucleoside triphosphate pyrophosphohydrolase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (491 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
APE08098.1Pyridoxamine 5'-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
APE08080.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (293 aa)
APE08079.1Aminodeoxychorismate synthase, component I; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
APE08067.1FABP family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
APE08049.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
APE11983.1Phosphoribosylglycinamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
APE08019.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (266 aa)
APE07992.1ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa)
APE11972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (998 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
APE07926.1Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (163 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (217 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (373 aa)
APE11958.1DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
APE07875.1RNA polymerase sigma factor SigJ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (308 aa)
APE07869.13-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (365 aa)
APE07847.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
APE07844.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
APE07840.1Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
APE11944.1FABP family protein; May play a role in the intracellular transport of hydrophobic ligands. (220 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (527 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (759 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (225 aa)
purSPhosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (81 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (295 aa)
APE11891.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (473 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (417 aa)
APE11885.1Nucleoside/nucleotide kinase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
APE11841.1Ketosteroid isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
APE11747.1CarD family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
dinB-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (418 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (277 aa)
APE11721.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
APE11720.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa)
APE11719.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa)
folEGTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
APE11716.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (184 aa)
APE11703.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
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