STRINGSTRING
APE07869.1 APE07869.1 APE11721.1 APE11721.1 APE11720.1 APE11720.1 APE11719.1 APE11719.1 asd asd APE11665.1 APE11665.1 APE11345.1 APE11345.1 gltD gltD APE11278.1 APE11278.1 APE10976.1 APE10976.1 aroD aroD APE08308.1 APE08308.1 APE08277.1 APE08277.1 dapD dapD aspA aspA APE08029.1 APE08029.1 APE11975.1 APE11975.1 APE08480.1 APE08480.1 APE08515.1 APE08515.1 lysA lysA APE08600.1 APE08600.1 APE12067.1 APE12067.1 APE08655.1 APE08655.1 APE08691.1 APE08691.1 APE08692.1 APE08692.1 APE12072.1 APE12072.1 APE08751.1 APE08751.1 APE08757.1 APE08757.1 APE08783.1 APE08783.1 dapB dapB dapA dapA dapF dapF APE08956.1 APE08956.1 aroC aroC aroK aroK aroB aroB ppc ppc APE09327.1 APE09327.1 nadA nadA APE09576.1 APE09576.1 APE12210.1 APE12210.1 APE09827.1 APE09827.1 aroA aroA APE10002.1 APE10002.1 APE10003.1 APE10003.1 APE10292.1 APE10292.1 aroQ aroQ aroE aroE APE10604.1 APE10604.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APE07869.13-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (365 aa)
APE11721.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
APE11720.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa)
APE11719.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (327 aa)
APE11665.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
APE11345.1FMN-binding glutamate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (518 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
APE11278.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1531 aa)
APE10976.1CoA ester lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (273 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (256 aa)
APE08308.1NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
APE08277.1Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (317 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (471 aa)
APE08029.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
APE11975.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
APE08480.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
APE08515.1Shikimate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (473 aa)
APE08600.1Dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
APE12067.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
APE08655.1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1602 aa)
APE08691.1Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
APE08692.1FMN-binding glutamate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (442 aa)
APE12072.1Protein glxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
APE08751.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (108 aa)
APE08757.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (81 aa)
APE08783.1CoA ester lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (277 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (244 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa)
APE08956.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (284 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (188 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (920 aa)
APE09327.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (343 aa)
APE09576.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa)
APE12210.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (459 aa)
APE09827.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa)
APE10002.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
APE10003.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M20A family. (386 aa)
APE10292.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
aroQType II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
APE10604.11-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (1103 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.