STRINGSTRING
APE08375.1 APE08375.1 APE10419.1 APE10419.1 APE10418.1 APE10418.1 cobH cobH APE12302.1 APE12302.1 APE12301.1 APE12301.1 APE10416.1 APE10416.1 APE10409.1 APE10409.1 metE metE metZ metZ APE10380.1 APE10380.1 thiE thiE APE10370.1 APE10370.1 APE10369.1 APE10369.1 thiG thiG APE10366.1 APE10366.1 APE10335.1 APE10335.1 aroE aroE aroQ aroQ APE12283.1 APE12283.1 APE10292.1 APE10292.1 APE10286.1 APE10286.1 gpmA gpmA proC proC APE10242.1 APE10242.1 APE10226.1 APE10226.1 menA menA APE10221.1 APE10221.1 menB menB menC menC menD menD menG menG APE10208.1 APE10208.1 APE10204.1 APE10204.1 APE10182.1 APE10182.1 APE10142.1 APE10142.1 APE10138.1 APE10138.1 APE10137.1 APE10137.1 APE10127.1 APE10127.1 APE12255.1 APE12255.1 APE12253.1 APE12253.1 APE10064.1 APE10064.1 APE10035.1 APE10035.1 folD folD metXA metXA APE10002.1 APE10002.1 APE12244.1 APE12244.1 aroA aroA APE09930.1 APE09930.1 APE09920.1 APE09920.1 APE09919.1 APE09919.1 APE09915.1 APE09915.1 APE09894.1 APE09894.1 APE09873.1 APE09873.1 APE12214.1 APE12214.1 APE09840.1 APE09840.1 APE09830.1 APE09830.1 ilvD ilvD APE09810.1 APE09810.1 APE09809.1 APE09809.1 ilvC ilvC APE07972.1 APE07972.1 APE11975.1 APE11975.1 APE07949.1 APE07949.1 APE11972.1 APE11972.1 BO226_00835 BO226_00835 APE07946.1 APE07946.1 APE07933.1 APE07933.1 APE07927.1 APE07927.1 pdxH pdxH serC serC APE07869.1 APE07869.1 APE07845.1 APE07845.1 APE07819.1 APE07819.1 APE08939.1 APE08939.1 APE08956.1 APE08956.1 aroC aroC aroK aroK aroB aroB APE08972.1 APE08972.1 carA carA carB carB APE08991.1 APE08991.1 APE08993.1 APE08993.1 APE08994.1 APE08994.1 ribBA ribBA ribH ribH APE08997.1 APE08997.1 tpiA tpiA APE09016.1 APE09016.1 APE09017.1 APE09017.1 APE09038.1 APE09038.1 APE09051.1 APE09051.1 APE09063.1 APE09063.1 APE09127.1 APE09127.1 APE09154.1 APE09154.1 APE09165.1 APE09165.1 APE09176.1 APE09176.1 APE09250.1 APE09250.1 ribH-2 ribH-2 APE09267.1 APE09267.1 hisE hisE hisG hisG APE09318.1 APE09318.1 APE09325.1 APE09325.1 APE09327.1 APE09327.1 APE09329.1 APE09329.1 APE09378.1 APE09378.1 APE09391.1 APE09391.1 argH argH argG argG argR argR argD argD argB argB argJ argJ argC argC APE09441.1 APE09441.1 trpA trpA trpB trpB trpC trpC trpE trpE hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD nadA nadA bioB bioB bioD bioD APE09527.1 APE09527.1 bioA bioA APE09540.1 APE09540.1 APE12187.1 APE12187.1 APE09576.1 APE09576.1 APE09581.1 APE09581.1 trpD trpD APE09595.1 APE09595.1 cobT cobT cobS cobS APE09602.1 APE09602.1 lipA lipA APE09609.1 APE09609.1 APE09613.1 APE09613.1 panB panB APE09662.1 APE09662.1 acpP acpP APE09664.1 APE09664.1 APE09676.1 APE09676.1 APE09750.1 APE09750.1 cysH cysH proA proA APE09795.1 APE09795.1 leuD leuD leuC leuC leuB leuB APE09806.1 APE09806.1 pdxT pdxT pdxS pdxS APE08916.1 APE08916.1 dxs dxs BO226_06235 BO226_06235 dapF dapF APE08838.1 APE08838.1 dapA dapA APE08831.1 APE08831.1 dapB dapB APE08818.1 APE08818.1 APE08744.1 APE08744.1 APE08731.1 APE08731.1 thiL thiL APE08719.1 APE08719.1 ectC ectC APE08717.1 APE08717.1 proB proB APE08704.1 APE08704.1 APE08694.1 APE08694.1 APE12072.1 APE12072.1 APE08692.1 APE08692.1 APE08691.1 APE08691.1 APE08656.1 APE08656.1 APE08654.1 APE08654.1 APE12067.1 APE12067.1 selD selD APE08600.1 APE08600.1 acpS acpS APE08594.1 APE08594.1 APE08558.1 APE08558.1 thrB thrB APE08540.1 APE08540.1 APE08539.1 APE08539.1 apt apt lysA lysA APE08516.1 APE08516.1 APE08515.1 APE08515.1 APE08510.1 APE08510.1 APE07979.1 APE07979.1 APE08019.1 APE08019.1 pgi pgi APE08049.1 APE08049.1 APE08098.1 APE08098.1 egtA egtA egtB egtB egtC egtC APE08106.1 APE08106.1 APE08124.1 APE08124.1 APE08130.1 APE08130.1 APE08131.1 APE08131.1 glyA glyA APE08146.1 APE08146.1 APE08148.1 APE08148.1 APE11998.1 APE11998.1 APE08154.1 APE08154.1 APE08263.1 APE08263.1 fbiC fbiC dapD dapD APE08277.1 APE08277.1 APE08315.1 APE08315.1 APE08324.1 APE08324.1 APE08328.1 APE08328.1 APE08334.1 APE08334.1 APE08363.1 APE08363.1 APE08374.1 APE08374.1 APE08476.1 APE08476.1 APE11939.1 APE11939.1 APE11852.1 APE11852.1 APE11849.1 APE11849.1 APE11816.1 APE11816.1 APE11790.1 APE11790.1 APE12497.1 APE12497.1 APE11772.1 APE11772.1 panD panD panC panC APE11721.1 APE11721.1 APE11720.1 APE11720.1 APE11719.1 APE11719.1 APE11716.1 APE11716.1 APE11707.1 APE11707.1 APE12486.1 APE12486.1 APE11692.1 APE11692.1 APE11673.1 APE11673.1 asd asd APE11665.1 APE11665.1 leuA-2 leuA-2 APE11658.1 APE11658.1 APE11624.1 APE11624.1 APE11623.1 APE11623.1 thiM thiM APE12466.1 APE12466.1 tgt tgt APE12458.1 APE12458.1 pat pat ilvD-2 ilvD-2 APE11550.1 APE11550.1 thiC thiC BO226_21450 BO226_21450 APE11408.1 APE11408.1 APE11406.1 APE11406.1 acpS-2 acpS-2 benD benD APE11379.1 APE11379.1 leuA leuA APE11345.1 APE11345.1 gltD gltD APE11278.1 APE11278.1 APE11262.1 APE11262.1 APE11256.1 APE11256.1 APE11148.1 APE11148.1 trpF trpF APE10939.1 APE10939.1 APE10908.1 APE10908.1 pheA pheA APE10874.1 APE10874.1 APE10871.1 APE10871.1 serS serS APE10846.1 APE10846.1 APE10802.1 APE10802.1 pgi-2 pgi-2 APE10675.1 APE10675.1 APE10668.1 APE10668.1 APE10658.1 APE10658.1 pckG pckG APE10638.1 APE10638.1 APE10636.1 APE10636.1 APE10635.1 APE10635.1 APE10620.1 APE10620.1 fabH fabH aroD aroD APE10573.1 APE10573.1 APE10545.1 APE10545.1 APE12320.1 APE12320.1 APE10480.1 APE10480.1 cobQ cobQ APE10426.1 APE10426.1 cobD cobD APE10422.1 APE10422.1 APE10420.1 APE10420.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APE08375.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
APE10419.1Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
APE10418.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
cobHCatalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
APE12302.1Cobalamin biosynthesis protein CobG; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
APE12301.1Cobaltochelatase subunit CobN; Derived by automated computational analysis using gene prediction method: Protein Homology. (1203 aa)
APE10416.1precorrin-6A synthase (deacetylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
APE10409.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (760 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (407 aa)
APE10380.1Adenosylcobinamide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (229 aa)
APE10370.1Glycine oxidase ThiO; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
APE10369.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (261 aa)
APE10366.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
APE10335.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
aroQType II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa)
APE12283.15-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (766 aa)
APE10292.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
APE10286.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (286 aa)
APE10242.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APE10226.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
menA1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (289 aa)
APE10221.1O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
menB1,4-dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (297 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (309 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (539 aa)
menGBifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (213 aa)
APE10208.1FAD-linked oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
APE10204.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (191 aa)
APE10182.14-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
APE10142.1Mycofactocin radical SAM maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
APE10138.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
APE10137.1Mycofactocin system creatininase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
APE10127.1Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (4665 aa)
APE12255.1Type VII secretion protein EccE; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
APE12253.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (390 aa)
APE10064.1tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
APE10035.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (375 aa)
APE10002.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
APE12244.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa)
APE09930.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (71 aa)
APE09920.1Adenylyltransferase/sulfurtransferase MoeZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
APE09919.1TIGR02569 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
APE09915.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
APE09894.1Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
APE09873.1Cobalamin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
APE12214.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
APE09840.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
APE09830.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (613 aa)
APE09810.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
APE09809.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
APE07972.1Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
APE11975.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
APE07949.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
APE11972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (998 aa)
BO226_00835Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
APE07946.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
APE07933.1acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
APE07927.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (217 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (373 aa)
APE07869.13-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (365 aa)
APE07845.1Asp/Glu racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
APE07819.1acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
APE08939.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
APE08956.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (284 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (188 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
APE08972.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (394 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1114 aa)
APE08991.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
APE08993.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (339 aa)
APE08994.1Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
ribBABifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (416 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (160 aa)
APE08997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
APE09016.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
APE09017.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
APE09038.1Enoyl-[acyl-carrier-protein] reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
APE09051.1Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4582 aa)
APE09063.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
APE09127.1Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
APE09154.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
APE09165.1Cobalamin biosynthesis protein CbiM; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
APE09176.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
APE09250.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (412 aa)
ribH-26,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (153 aa)
APE09267.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1189 aa)
hisEphosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (287 aa)
APE09318.1precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
APE09325.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
APE09327.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
APE09329.1Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (7349 aa)
APE09378.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
APE09391.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (169 aa)
argDAspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (312 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (416 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (357 aa)
APE09441.13-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (269 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (531 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (120 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (375 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (343 aa)
bioBBiotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (337 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (237 aa)
APE09527.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (429 aa)
APE09540.1Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
APE12187.1Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (307 aa)
APE09576.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa)
APE09581.1Polyketide cyclase / dehydrase and lipid transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (359 aa)
APE09595.1Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (363 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (254 aa)
APE09602.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (336 aa)
APE09609.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
APE09613.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (445 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (286 aa)
APE09662.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (92 aa)
APE09664.1FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (414 aa)
APE09676.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
APE09750.1Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (268 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (242 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (427 aa)
APE09795.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (336 aa)
APE09806.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (212 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (301 aa)
APE08916.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
BO226_06235F420-dependent oxidoreductase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (397 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa)
APE08838.1N-acetylglutamate synthase; Catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (162 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
APE08831.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (244 aa)
APE08818.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (300 aa)
APE08744.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
APE08731.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1133 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (323 aa)
APE08719.1Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (132 aa)
APE08717.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
APE08704.1Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
APE08694.1Type III glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (458 aa)
APE12072.1Protein glxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
APE08692.1FMN-binding glutamate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (442 aa)
APE08691.1Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
APE08656.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
APE08654.14-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
APE12067.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
selDSelenide, water dikinase SelD; Synthesizes selenophosphate from selenide and ATP. (340 aa)
APE08600.1Dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
acpSholo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (135 aa)
APE08594.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3103 aa)
APE08558.1ATP:cob(I)alamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)
APE08540.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (363 aa)
APE08539.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (185 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (473 aa)
APE08516.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
APE08515.1Shikimate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
APE08510.14-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
APE07979.1Class II glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
APE08019.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (547 aa)
APE08049.1Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
APE08098.1Pyridoxamine 5'-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
egtAErgothioneine biosynthesis glutamate--cysteine ligase EgtA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (409 aa)
egtBSulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (430 aa)
egtCErgothioneine biosynthesis protein EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (249 aa)
APE08106.1Dimethylhistidine N-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APE08124.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
APE08130.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
APE08131.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
APE08146.1Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine; Belongs to the PanD family. (36 aa)
APE08148.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (3541 aa)
APE11998.1Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4075 aa)
APE08154.1Fructose-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
APE08263.14a-hydroxytetrahydrobiopterin dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
fbiC7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (317 aa)
APE08277.1Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
APE08315.1Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (597 aa)
APE08324.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
APE08328.1FAD-linked oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
APE08334.1TrpB-like pyridoxal-phosphate dependent enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa)
APE08363.13-ketoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
APE08374.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
APE08476.1Sulfite reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
APE11939.14-amino-4-deoxychorismate lyase; Catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
APE11852.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
APE11849.1Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
APE11816.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
APE11790.12,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APE12497.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
APE11772.1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (145 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (312 aa)
APE11721.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
APE11720.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa)
APE11719.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa)
APE11716.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (184 aa)
APE11707.1Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1301 aa)
APE12486.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
APE11692.1Inhibition of morphological differentiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
APE11673.1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (327 aa)
APE11665.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (603 aa)
APE11658.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
APE11624.1CDP-alcohol phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
APE11623.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (281 aa)
APE12466.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (243 aa)
tgttRNA-guanine(34) transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form [...] (414 aa)
APE12458.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
patHistidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
ilvD-2Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (565 aa)
APE11550.1Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (594 aa)
BO226_21450Cytochrome; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
APE11408.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
APE11406.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
acpS-2Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (142 aa)
benD1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa)
APE11379.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (594 aa)
APE11345.1FMN-binding glutamate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (518 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
APE11278.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1531 aa)
APE11262.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
APE11256.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
APE11148.1Inositol 1-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (201 aa)
APE10939.1Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
APE10908.1Carbamoyl-phosphate-synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1060 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
APE10874.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
APE10871.1NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa)
APE10846.1Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1653 aa)
APE10802.1NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
pgi-2Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (550 aa)
APE10675.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
APE10668.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (148 aa)
APE10658.1Cobalamin biosynthesis protein CbiM; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
APE10638.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
APE10636.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
APE10635.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
APE10620.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (340 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (256 aa)
APE10573.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (78 aa)
APE10545.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
APE12320.1Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (6249 aa)
APE10480.1Lactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (492 aa)
APE10426.1precorrin-6A reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (305 aa)
APE10422.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
APE10420.1Cobalamin biosynthesis bifunctional protein CbiET; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
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