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| | trpF | Phosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (201 aa) |
| | APE09051.1 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4582 aa) |
| | APE09038.1 | Enoyl-[acyl-carrier-protein] reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa) |
| | APE09016.1 | NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1114 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (394 aa) |
| | APE08972.1 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | hisC | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (375 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa) |
| | nadA | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (343 aa) |
| | bioB | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (337 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (237 aa) |
| | APE09527.1 | 8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | bioA | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (429 aa) |
| | APE09540.1 | Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa) |
| | APE12187.1 | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (307 aa) |
| | APE09576.1 | 3-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (359 aa) |
| | APE09595.1 | Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa) |
| | APE09602.1 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (336 aa) |
| | APE09609.1 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa) |
| | APE09613.1 | Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (445 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (286 aa) |
| | APE09662.1 | ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (92 aa) |
| | APE09664.1 | FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (414 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (242 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (427 aa) |
| | APE09795.1 | Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (336 aa) |
| | APE09806.1 | Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa) |
| | APE09809.1 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa) |
| | APE09810.1 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (613 aa) |
| | APE09830.1 | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa) |
| | APE12214.1 | Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa) |
| | APE09894.1 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa) |
| | APE09915.1 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | APE09919.1 | TIGR02569 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa) |
| | APE09920.1 | Adenylyltransferase/sulfurtransferase MoeZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa) |
| | APE12244.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa) |
| | APE10002.1 | N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (375 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) |
| | APE10064.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa) |
| | APE12253.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (390 aa) |
| | APE12255.1 | Type VII secretion protein EccE; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa) |
| | APE10127.1 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (4665 aa) |
| | APE10138.1 | GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa) |
| | APE10142.1 | Mycofactocin radical SAM maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa) |
| | APE10182.1 | 4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa) |
| | APE10204.1 | Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (191 aa) |
| | APE10226.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | APE10242.1 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (286 aa) |
| | APE10292.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa) |
| | APE12283.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (766 aa) |
| | aroQ | Type II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa) |
| | APE10335.1 | Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (407 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (760 aa) |
| | APE10409.1 | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | APE12302.1 | Cobalamin biosynthesis protein CobG; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa) |
| | APE10480.1 | Lactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa) |
| | APE12320.1 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (6249 aa) |
| | APE10545.1 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa) |
| | APE10573.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (78 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (256 aa) |
| | fabH | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (340 aa) |
| | APE10620.1 | Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa) |
| | APE10635.1 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa) |
| | APE10636.1 | Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | APE10668.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (148 aa) |
| | APE10675.1 | Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa) |
| | APE10802.1 | NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa) |
| | APE10846.1 | Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1653 aa) |
| | serS | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa) |
| | APE10871.1 | NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | APE10874.1 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa) |
| | pheA | Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa) |
| | APE10908.1 | Carbamoyl-phosphate-synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1060 aa) |
| | APE09063.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa) |
| | APE11256.1 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa) |
| | APE11262.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | APE11278.1 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1531 aa) |
| | gltD | Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa) |
| | APE11345.1 | FMN-binding glutamate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (518 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (594 aa) |
| | benD | 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa) |
| | acpS-2 | Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (142 aa) |
| | APE11406.1 | Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa) |
| | APE11408.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa) |
| | BO226_21450 | Cytochrome; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | APE11550.1 | Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (565 aa) |
| | pat | Histidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa) |
| | APE12458.1 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa) |
| | APE11623.1 | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (603 aa) |
| | APE11665.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (327 aa) |
| | APE11673.1 | FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa) |
| | APE11692.1 | Inhibition of morphological differentiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa) |
| | APE11707.1 | Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1301 aa) |
| | APE11719.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa) |
| | APE11720.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa) |
| | APE11721.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (312 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (145 aa) |
| | APE11772.1 | FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa) |
| | APE11790.1 | 2,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | APE11816.1 | acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa) |
| | APE11849.1 | Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa) |
| | APE11852.1 | acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa) |
| | APE11939.1 | 4-amino-4-deoxychorismate lyase; Catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa) |
| | APE07819.1 | acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa) |
| | APE07845.1 | Asp/Glu racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa) |
| | APE07869.1 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (365 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (373 aa) |
| | APE07933.1 | acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa) |
| | APE07946.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | BO226_00835 | Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa) |
| | APE11972.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (998 aa) |
| | APE07949.1 | 3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa) |
| | APE11975.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa) |
| | APE07972.1 | Quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | APE08019.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa) |
| | APE08106.1 | Dimethylhistidine N-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa) |
| | APE08130.1 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa) |
| | APE08131.1 | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | APE08146.1 | Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine; Belongs to the PanD family. (36 aa) |
| | APE08148.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (3541 aa) |
| | APE11998.1 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4075 aa) |
| | fbiC | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (317 aa) |
| | APE08277.1 | Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa) |
| | APE08315.1 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (597 aa) |
| | APE08328.1 | FAD-linked oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | APE08334.1 | TrpB-like pyridoxal-phosphate dependent enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa) |
| | APE08363.1 | 3-ketoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa) |
| | APE08374.1 | acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa) |
| | APE08375.1 | acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa) |
| | APE08476.1 | Sulfite reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa) |
| | APE08515.1 | Shikimate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa) |
| | APE08516.1 | NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (473 aa) |
| | APE08539.1 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa) |
| | APE08540.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (363 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | APE08594.1 | 3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3103 aa) |
| | acpS | holo-ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (135 aa) |
| | APE08600.1 | Dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa) |
| | selD | Selenide, water dikinase SelD; Synthesizes selenophosphate from selenide and ATP. (340 aa) |
| | APE12067.1 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa) |
| | APE08691.1 | Allantoate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa) |
| | APE08692.1 | FMN-binding glutamate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (442 aa) |
| | APE12072.1 | Protein glxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | APE08694.1 | Type III glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (458 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | ectC | L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (132 aa) |
| | APE08719.1 | Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa) |
| | APE08744.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (244 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa) |
| | APE08838.1 | N-acetylglutamate synthase; Catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (162 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa) |
| | BO226_06235 | F420-dependent oxidoreductase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (397 aa) |
| | APE08956.1 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (284 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (188 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (120 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (531 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (269 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | APE09441.1 | 3-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (357 aa) |
| | argJ | Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (416 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (312 aa) |
| | argD | Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (169 aa) |
| | argG | Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | argH | Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa) |
| | APE09329.1 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (7349 aa) |
| | APE09327.1 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa) |
| | APE09325.1 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa) |
| | APE09318.1 | precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (287 aa) |
| | hisE | phosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa) |
| | APE09267.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1189 aa) |
| | APE09250.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (412 aa) |
| | APE09176.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa) |
| | APE09154.1 | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
