STRINGSTRING
APE07903.1 APE07903.1 APE07991.1 APE07991.1 APE07992.1 APE07992.1 APE11987.1 APE11987.1 APE08215.1 APE08215.1 APE08302.1 APE08302.1 rho rho APE08710.1 APE08710.1 lig lig recG recG APE08763.1 APE08763.1 nusA nusA pnp pnp APE08898.1 APE08898.1 APE08903.1 APE08903.1 ruvA ruvA aspS aspS efp efp APE09044.1 APE09044.1 APE09111.1 APE09111.1 APE09173.1 APE09173.1 arc arc pheT pheT APE09436.1 APE09436.1 APE09619.1 APE09619.1 recO recO ligA ligA infA infA rpsQ rpsQ rplB rplB rpsL rpsL APE10534.1 APE10534.1 APE10731.1 APE10731.1 APE11131.1 APE11131.1 APE11157.1 APE11157.1 lysS lysS APE11700.1 APE11700.1 lysS-2 lysS-2 APE11764.1 APE11764.1 APE11832.1 APE11832.1 APE11845.1 APE11845.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APE07903.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
APE07991.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
APE07992.1ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa)
APE11987.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
APE08215.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (359 aa)
APE08302.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (388 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (654 aa)
APE08710.1Derived by automated computational analysis using gene prediction method: Protein Homology. (1127 aa)
ligATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (763 aa)
APE08763.1RNA-binding transcriptional accessory protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (786 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (342 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (761 aa)
APE08898.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
APE08903.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (427 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (198 aa)
aspSaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (187 aa)
APE09044.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
APE09111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
APE09173.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
arcProteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (589 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (828 aa)
APE09436.130S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
APE09619.1Ribonuclease II; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (268 aa)
ligADNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (702 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (94 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
APE10534.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
APE10731.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
APE11131.1Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
APE11157.1Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (357 aa)
lysSlysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (1096 aa)
APE11700.1Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
lysS-2lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (503 aa)
APE11764.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
APE11832.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
APE11845.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.