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APE07869.1 APE07869.1 APE08029.1 APE08029.1 APE08334.1 APE08334.1 APE08480.1 APE08480.1 APE08515.1 APE08515.1 APE08801.1 APE08801.1 APE08956.1 APE08956.1 aroC aroC aroK aroK aroB aroB APE09325.1 APE09325.1 APE09327.1 APE09327.1 trpA trpA trpB trpB trpC trpC trpE trpE hisA hisA hisC hisC APE09576.1 APE09576.1 trpD trpD aroA aroA APE09973.1 APE09973.1 aroQ aroQ aroE aroE APE12305.1 APE12305.1 aroD aroD pheA pheA trpF trpF pat pat APE12458.1 APE12458.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APE07869.13-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (365 aa)
APE08029.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
APE08334.1TrpB-like pyridoxal-phosphate dependent enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa)
APE08480.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
APE08515.1Shikimate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
APE08801.1FUSC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
APE08956.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (284 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (395 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (188 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
APE09325.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
APE09327.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (269 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (531 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (375 aa)
APE09576.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (359 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa)
APE09973.1Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (220 aa)
aroQType II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (156 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
APE12305.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (256 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (201 aa)
patHistidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
APE12458.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
Your Current Organism:
Rhodococcus sp. 2G
NCBI taxonomy Id: 1570939
Other names: R. sp. 2G
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