(45 nodes) Short-chain dehydrogenase/reductase, conserved site network (Streptomyces sp. PBH53)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fabG-2	3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	AKN69951.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	AKN70128.1	Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (286 aa)
	AKN70158.1	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	ispD	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the short-chain dehydrogenases/reductases (SDR) family. (498 aa)
	AKN70716.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
	AKN70824.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	AKN70945.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	AKN71563.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
	AKN71626.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
	AKN71681.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	AKN71839.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
	AKN71845.1	Ketoacyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa)
	AKN71859.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
	AKN72315.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
	AKN72475.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa)
	AKN72666.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	AKN72808.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	AKN72848.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
	AKN75576.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
	AKN72855.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (301 aa)
	AKN73262.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
	AKN75625.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	AKN73311.1	3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (234 aa)
	AKN73533.1	3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
	AKN73534.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
	AKN75708.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	AKN73868.1	3-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
	AKN74040.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
	AKN74321.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
	AKN74361.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (279 aa)
	AKN74544.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (239 aa)
	AKN74603.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
	AKN74817.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
	AKN74649.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
	AKN68471.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
	AKN68539.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
	AKN68575.1	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
	fabG	3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
	AKN68839.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
	AKN68979.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
	AKN69076.1	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
	AKN69255.1	3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa)
	AKN74849.1	Ketoacyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
	AKN69400.1	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)

Your Current Organism:

Streptomyces sp. PBH53

NCBI taxonomy Id: 1577075
Other names: S. sp. PBH53

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKN68471.1	AKN69076.1	QR97_00335	QR97_03955	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.440
AKN68539.1	AKN69076.1	QR97_00740	QR97_03955	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.465
AKN68539.1	AKN69255.1	QR97_00740	QR97_04980	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.463
AKN68539.1	AKN69951.1	QR97_00740	QR97_08995	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
AKN68539.1	AKN70158.1	QR97_00740	QR97_10225	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.713
AKN68539.1	AKN72475.1	QR97_00740	QR97_24305	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.481
AKN68539.1	AKN74361.1	QR97_00740	QR97_35650	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.490
AKN68539.1	AKN74544.1	QR97_00740	QR97_36745	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.479
AKN68539.1	AKN75625.1	QR97_00740	QR97_29260	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
AKN68575.1	AKN68839.1	QR97_00955	QR97_02585	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.443
AKN68575.1	AKN69076.1	QR97_00955	QR97_03955	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.484
AKN68575.1	AKN69255.1	QR97_00955	QR97_04980	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.473
AKN68575.1	AKN69951.1	QR97_00955	QR97_08995	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.457
AKN68575.1	AKN70158.1	QR97_00955	QR97_10225	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.496
AKN68575.1	AKN72315.1	QR97_00955	QR97_23300	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449
AKN68575.1	AKN72475.1	QR97_00955	QR97_24305	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.472
AKN68575.1	AKN74361.1	QR97_00955	QR97_35650	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.473
AKN68575.1	AKN74544.1	QR97_00955	QR97_36745	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.462
AKN68575.1	AKN75625.1	QR97_00955	QR97_29260	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.754
AKN68839.1	AKN68575.1	QR97_02585	QR97_00955	Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.443