STRINGSTRING
acsA acsA AKN71252.1 AKN71252.1 AKN71404.1 AKN71404.1 AKN71435.1 AKN71435.1 AKN71451.1 AKN71451.1 AKN71631.1 AKN71631.1 AKN71651.1 AKN71651.1 AKN71687.1 AKN71687.1 AKN71704.1 AKN71704.1 AKN71827.1 AKN71827.1 AKN71961.1 AKN71961.1 AKN71962.1 AKN71962.1 AKN72126.1 AKN72126.1 AKN72163.1 AKN72163.1 AKN72173.1 AKN72173.1 AKN72228.1 AKN72228.1 AKN72271.1 AKN72271.1 AKN72377.1 AKN72377.1 sucD sucD sucC sucC AKN72577.1 AKN72577.1 AKN72748.1 AKN72748.1 AKN72767.1 AKN72767.1 AKN72854.1 AKN72854.1 AKN73006.1 AKN73006.1 AKN73154.1 AKN73154.1 AKN73157.1 AKN73157.1 AKN73333.1 AKN73333.1 AKN73545.1 AKN73545.1 AKN73581.1 AKN73581.1 AKN73622.1 AKN73622.1 AKN73893.1 AKN73893.1 AKN74099.1 AKN74099.1 AKN74135.1 AKN74135.1 AKN74136.1 AKN74136.1 AKN74153.1 AKN74153.1 AKN74507.1 AKN74507.1 AKN74531.1 AKN74531.1 AKN74650.1 AKN74650.1 AKN74535.1 AKN74535.1 AKN68873.1 AKN68873.1 AKN68972.1 AKN68972.1 AKN68994.1 AKN68994.1 AKN69066.1 AKN69066.1 AKN69337.1 AKN69337.1 AKN69355.1 AKN69355.1 AKN69359.1 AKN69359.1 AKN69542.1 AKN69542.1 AKN69558.1 AKN69558.1 AKN69599.1 AKN69599.1 AKN75193.1 AKN75193.1 AKN69851.1 AKN69851.1 AKN74863.1 AKN74863.1 AKN69852.1 AKN69852.1 AKN69865.1 AKN69865.1 ackA ackA AKN69873.1 AKN69873.1 AKN69996.1 AKN69996.1 AKN70138.1 AKN70138.1 AKN70313.1 AKN70313.1 AKN70378.1 AKN70378.1 AKN70499.1 AKN70499.1 AKN70756.1 AKN70756.1 AKN70845.1 AKN70845.1 AKN70967.1 AKN70967.1 AKN75350.1 AKN75350.1 AKN70996.1 AKN70996.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
AKN71252.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa)
AKN71404.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
AKN71435.1Molecular chaperone GroES; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
AKN71451.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (727 aa)
AKN71631.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
AKN71651.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
AKN71687.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AKN71704.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
AKN71827.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
AKN71961.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
AKN71962.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
AKN72126.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AKN72163.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (709 aa)
AKN72173.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AKN72228.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AKN72271.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
AKN72377.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (977 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
AKN72577.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AKN72748.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AKN72767.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
AKN72854.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AKN73006.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
AKN73154.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AKN73157.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AKN73333.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
AKN73545.1Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
AKN73581.1Peptidase U61; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
AKN73622.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AKN73893.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
AKN74099.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
AKN74135.1ATP-grasp domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AKN74136.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
AKN74153.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
AKN74507.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (896 aa)
AKN74531.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AKN74650.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
AKN74535.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AKN68873.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
AKN68972.1Peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (416 aa)
AKN68994.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AKN69066.1Peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (427 aa)
AKN69337.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
AKN69355.1acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
AKN69359.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
AKN69542.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
AKN69558.1Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
AKN69599.1acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa)
AKN75193.1Peptidase S66 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
AKN69851.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AKN74863.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
AKN69852.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
AKN69865.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
AKN69873.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (700 aa)
AKN69996.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
AKN70138.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
AKN70313.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AKN70378.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
AKN70499.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AKN70756.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
AKN70845.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
AKN70967.1pimeloyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (739 aa)
AKN75350.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AKN70996.1acetyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
Your Current Organism:
Streptomyces sp. PBH53
NCBI taxonomy Id: 1577075
Other names: S. sp. PBH53
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