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| | SDR24243.1 | Shikimate dehydrogenase. (287 aa) |
| | SDR62824.1 | Transposase. (471 aa) |
| | SDR62697.1 | Transposase. (340 aa) |
| | SDR62676.1 | Cystathionine beta-lyase. (399 aa) |
| | SDR62632.1 | Transposase. (349 aa) |
| | SDR62619.1 | Cystathionine beta-synthase. (329 aa) |
| | SDR62595.1 | Transposase. (347 aa) |
| | SDR62590.1 | Transposase. (62 aa) |
| | SDR62583.1 | Transposase. (119 aa) |
| | SDR62570.1 | Transposase. (379 aa) |
| | SDR62519.1 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (382 aa) |
| | SDR62287.1 | Transposase. (339 aa) |
| | SDR62283.1 | Transposase. (81 aa) |
| | SDR62211.1 | Hypothetical protein. (126 aa) |
| | SDR61775.1 | Transposase. (338 aa) |
| | eno-2 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | SDR61622.1 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa) |
| | SDR61597.1 | Aspartate aminotransferase. (400 aa) |
| | SDR61485.1 | Transposase. (449 aa) |
| | SDR61451.1 | Transposase. (370 aa) |
| | SDR61443.1 | Hypothetical protein. (67 aa) |
| | SDR61431.1 | Transposase. (376 aa) |
| | SDR61216.1 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (311 aa) |
| | SDR61167.1 | Transposase; Non-canonical start codon; manually curated. (340 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (210 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa) |
| | SDR61150.1 | Citrate synthase. (271 aa) |
| | SDR61073.1 | Transposase. (274 aa) |
| | SDR61071.1 | Transposase. (360 aa) |
| | SDR61069.1 | Transposase. (378 aa) |
| | SDR60985.1 | Transposase. (376 aa) |
| | SDR60867.1 | Ketol-acid reductoisomerase. (276 aa) |
| | SDR60219.1 | Aromatic-amino-acid transaminase. (401 aa) |
| | SDR60113.1 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1170 aa) |
| | proB-2 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa) |
| | SDR59417.1 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (573 aa) |
| | SDR59350.1 | Uncharacterized conserved protein, contains tandem ACT domains. (140 aa) |
| | SDR59163.1 | Hypothetical protein. (285 aa) |
| | SDR59051.1 | Aconitase; Belongs to the aconitase/IPM isomerase family. (861 aa) |
| | SDR59019.1 | Acetolactate synthase-1/2/3 large subunit; Manually curated; Belongs to the TPP enzyme family. (582 aa) |
| | aroQ-3 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) |
| | SDR56807.1 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (464 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa) |
| | SDR56636.1 | Fructose-bisphosphate aldolase. (339 aa) |
| | SDR56492.1 | Transketolase; Belongs to the transketolase family. (693 aa) |
| | SDR56454.1 | Aromatic acid exporter family member 1. (355 aa) |
| | SDR56340.1 | Aromatic-amino-acid transaminase. (399 aa) |
| | SDR56267.1 | Acetyltransferase (GNAT) domain-containing protein. (146 aa) |
| | SDR56167.1 | Fusaric acid resistance protein-like. (190 aa) |
| | SDR56088.1 | Citrate synthase; Belongs to the citrate synthase family. (463 aa) |
| | SDR55229.1 | L-threonine aldolase. (342 aa) |
| | SDR54811.1 | Shikimate dehydrogenase. (282 aa) |
| | SDR54153.1 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa) |
| | SDR54146.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa) |
| | SDR54074.1 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Belongs to the HisA/HisF family. (249 aa) |
| | pqqC | Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (252 aa) |
| | SDR53065.1 | Transposase. (383 aa) |
| | thrB | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. (331 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (243 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (373 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (217 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | SDR51905.1 | Citrate synthase; Belongs to the citrate synthase family. (433 aa) |
| | SDR51845.1 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa) |
| | SDR51318.1 | Hopanoid-associated phosphorylase. (252 aa) |
| | SDR51112.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (560 aa) |
| | SDR50980.1 | Cystathionine beta-lyase. (387 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | SDR50704.1 | Transposase. (338 aa) |
| | SDR50046.1 | L-threonine ammonia-lyase. (343 aa) |
| | SDR50041.1 | Ornithine cyclodeaminase. (334 aa) |
| | SDR49749.1 | Pyrroloquinoline-quinone synthase. (243 aa) |
| | SDR49729.1 | Ornithine cyclodeaminase. (314 aa) |
| | SDR49337.1 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa) |
| | ilvD-2 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (620 aa) |
| | SDR49111.1 | Citrate synthase. (414 aa) |
| | SDR49034.1 | Transketolase subunit A. (281 aa) |
| | SDR49028.1 | Transketolase subunit B. (333 aa) |
| | SDR48581.1 | Serine O-acetyltransferase. (308 aa) |
| | aroQ-2 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | aroE-2 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (316 aa) |
| | SDR46504.1 | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit. (651 aa) |
| | SDR46429.1 | L-glutamine synthetase. (444 aa) |
| | SDR46368.1 | Aconitase. (654 aa) |
| | SDR46235.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (372 aa) |
| | SDR46185.1 | Ribosomal-protein-alanine N-acetyltransferase. (169 aa) |
| | SDR45953.1 | Transposase. (376 aa) |
| | SDR45016.1 | Transposase. (338 aa) |
| | SDR44473.1 | Glutamine synthetase. (501 aa) |
| | SDR44236.1 | Predicted arabinose efflux permease, MFS family. (449 aa) |
| | ilvA-2 | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (528 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (444 aa) |
| | SDR23653.1 | (S)-sulfolactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa) |
| | hisD-2 | Sulfopropanediol 3-dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa) |
| | SDR20820.1 | Acetylornithine deacetylase. (410 aa) |
| | SDR20804.1 | Threonine dehydratase. (344 aa) |
| | SDR20483.1 | Phosphoserine phosphatase. (279 aa) |
| | SDR20425.1 | Cystathionine beta-lyase. (394 aa) |
| | SDR19407.1 | L-threonine synthase. (483 aa) |
| | SDR19388.1 | Homoserine dehydrogenase. (443 aa) |
| | SDR19369.1 | Alanine-synthesizing transaminase. (415 aa) |
| | SDR17463.1 | Hypothetical protein. (542 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa) |
| | SDR15567.1 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (125 aa) |
| | SDR14036.1 | Protein of unknown function. (337 aa) |
| | SDR12772.1 | Hypothetical protein. (140 aa) |
| | SDR12695.1 | Aspartate/methionine/tyrosine aminotransferase. (406 aa) |
| | SDR08289.1 | Acetyltransferase (GNAT) family protein. (187 aa) |
| | SDR07553.1 | Transposase. (376 aa) |
| | SDR07001.1 | Aromatic-amino-acid transaminase. (399 aa) |
| | SDR06347.1 | 2-keto-4-methylthiobutyrate aminotransferase apoenzyme. (390 aa) |
| | SDR06233.1 | Probable phosphoglycerate mutase. (238 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | SDR05053.1 | Acetolactate synthase, small subunit. (163 aa) |
| | SDR05022.1 | Acetolactate synthase, large subunit. (587 aa) |
| | SDR04060.1 | Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (209 aa) |
| | SDR03331.1 | MFS-type transporter involved in bile tolerance, Atg22 family. (406 aa) |
| | SDR02888.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (550 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | SDR02121.1 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (746 aa) |
| | SDR00197.1 | Putative endonuclease. (105 aa) |
| | SDQ99900.1 | ACT domain-containing protein. (140 aa) |
| | argH | Argininosuccinate lyase. (468 aa) |
| | ilvD | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (557 aa) |
| | SDQ95457.1 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (196 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | SDQ91764.1 | Transposase. (402 aa) |
| | SDQ90385.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (280 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (507 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa) |
| | hisC-3 | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (359 aa) |
| | SDQ85339.1 | Anthranilate phosphoribosyltransferase. (391 aa) |
| | SDQ85307.1 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). (361 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa) |
| | SDQ82429.1 | Methionine synthase (B12-dependent). (356 aa) |
| | SDQ82403.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (905 aa) |
| | srkA | Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (348 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (315 aa) |
| | SDQ72564.1 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa) |
| | SDQ72535.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (581 aa) |
| | SDQ72281.1 | Cyclohexadienyl dehydratase; Belongs to the bacterial solute-binding protein 3 family. (263 aa) |
| | SDQ69209.1 | 2-keto-4-methylthiobutyrate aminotransferase apoenzyme. (384 aa) |
| | SDQ68819.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa) |
| | metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (381 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (341 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | aroK-2 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (183 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa) |
| | SDQ64494.1 | Glutamate synthase (NADH) large subunit. (1567 aa) |
| | SDQ64461.1 | Glutamate synthase (NADH) small subunit. (489 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (233 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (444 aa) |
| | hisC-2 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (250 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (136 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (131 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (261 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (343 aa) |
| | SDQ61492.1 | Anthranilate synthase, component II. (205 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (497 aa) |
| | SDQ61387.1 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa) |
| | argJ | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (287 aa) |
| | SDQ57637.1 | Transketolase; Belongs to the transketolase family. (673 aa) |
| | SDQ57605.1 | Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (265 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (423 aa) |
| | SDQ56375.1 | Phosphoglycerate mutase. (222 aa) |
| | ilvE | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | SDQ53922.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa) |
| | SDQ53891.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | SDQ51197.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (309 aa) |
| | SDQ51152.1 | Protein of unknown function. (115 aa) |
| | SDQ50393.1 | Citrate synthase. (413 aa) |
| | SDQ49893.1 | Isocitrate dehydrogenase (NADP). (418 aa) |
| | SDQ48867.1 | Ribosomal protein S18 acetylase RimI. (157 aa) |
| | argD | Acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (394 aa) |
| | SDQ48639.1 | Predicted arabinose efflux permease, MFS family. (422 aa) |
| | SDQ48095.1 | Protein N-acetyltransferase, RimJ/RimL family. (177 aa) |
| | SDQ47363.1 | Threonine dehydratase. (321 aa) |
| | SDQ47234.1 | Aspartate/methionine/tyrosine aminotransferase. (398 aa) |
| | SDQ46035.1 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (198 aa) |
| | serC | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa) |
| | SDQ43537.1 | Chorismate mutase. (359 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (373 aa) |
| | SDQ43466.1 | Prephenate dehydrogenase. (341 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (434 aa) |
| | SDQ43071.1 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (300 aa) |
| | SDQ40448.1 | Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (205 aa) |
| | SDQ37315.1 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (343 aa) |
| | SDQ36558.1 | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (264 aa) |
| | SDQ35810.1 | CBS domain-containing protein. (155 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (568 aa) |
| | argA | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. (462 aa) |
| | SDQ32939.1 | L-glutamine synthetase. (471 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (305 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (383 aa) |
| | SDQ29859.1 | Serine O-acetyltransferase. (275 aa) |
| | SDQ29589.1 | Aspartate kinase; Belongs to the aspartokinase family. (416 aa) |
| | dapE | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (379 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (275 aa) |
| | SDQ27709.1 | Succinyldiaminopimelate aminotransferase apoenzyme. (406 aa) |
