STRINGSTRING
CEN55168.1 CEN55168.1 prlC prlC CEN55171.1 CEN55171.1 CEN55172.1 CEN55172.1 ptsH ptsH CEN55174.1 CEN55174.1 yhbJ yhbJ hprK hprK yhbH yhbH lptB lptB ltpA ltpA CEN55181.1 CEN55181.1 kdsC kdsC kdsD kdsD CEN55184.1 CEN55184.1 CEN55185.1 CEN55185.1 aspH aspH CEN55225.1 CEN55225.1 CEN55226.1 CEN55226.1 lptE lptE lptD lptD lpxK lpxK kdsB kdsB kdsA kdsA bamD bamD BN1209_0858 BN1209_0858 lpxD lpxD fabZ fabZ lpxA lpxA CEN56136.1 CEN56136.1 CEN56201.1 CEN56201.1 bamE bamE waaD waaD gmhA gmhA hldE hldE waaF waaF CEN56346.1 CEN56346.1 CEN56347.1 CEN56347.1 CEN56349.1 CEN56349.1 CEN56350.1 CEN56350.1 waaC waaC CEN56352.1 CEN56352.1 CEN56392.1 CEN56392.1 lpxC lpxC pyrC-2 pyrC-2 yraL yraL lppC lppC yraN yraN yraO yraO CEN56587.1 CEN56587.1 waaA waaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CEN55168.1Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily. (376 aa)
prlCOligopeptidase A. (686 aa)
CEN55171.1PEP-protein phosphotransferase of PTS system (enzyme I) (fragment). (309 aa)
CEN55172.1Phosphoenolpyruvate-protein phosphotransferase (fragment); Belongs to the PEP-utilizing enzyme family. (221 aa)
ptsHPhosphocarrier protein HPr. (88 aa)
CEN55174.1PTS system fructose subfamily IIA component. (141 aa)
yhbJHypothetical protein; Displays ATPase and GTPase activities. (279 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (316 aa)
yhbHRibosome-associated, sigma 54 modulation protein; Function of strongly homologous gene; factor. (108 aa)
lptBPutative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (240 aa)
ltpALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (177 aa)
CEN55181.1Homologs of previously reported genes of unknown function. (243 aa)
kdsC3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (179 aa)
kdsDD-arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily. (360 aa)
CEN55184.1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (657 aa)
CEN55185.1Homologs of previously reported genes of unknown function. (362 aa)
aspHFe(2+)/alpha-ketoglutarate-dependent dioxygenase lpxO. (314 aa)
CEN55225.1Permease YjgP/YjgQ family protein. (361 aa)
CEN55226.1Permease YjgP/YjgQ family protein. (362 aa)
lptERare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (167 aa)
lptDLPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (856 aa)
lpxKLipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (333 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (254 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (279 aa)
bamDOuter membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (268 aa)
BN1209_0858Outer membrane chaperone Skp (OmpH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component;fragment of putative outer membrane protein (part 2); Belongs to the skp family. (167 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (343 aa)
fabZ(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa)
lpxAUDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (261 aa)
CEN56136.1Uncharacterized lipoprotein. (408 aa)
CEN56201.1Putative Glycine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (372 aa)
bamEExported protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (481 aa)
waaDADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (322 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (187 aa)
hldEBifunctional protein HldE [Includes: D-beta-D-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (487 aa)
waaFADP-heptose:LPS heptosyltransferase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (344 aa)
CEN56346.13-deoxy-D-manno-octulosonic-acid transferase. (256 aa)
CEN56347.1Putative O-antigen polymerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (406 aa)
CEN56349.1Candidate b-1,4-glucosyltransferase, Glycosyltransferase Family 2. (248 aa)
CEN56350.1Glycosyl transferase family 9. (352 aa)
waaCADP-heptose:LPS heptosyl transferase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (323 aa)
CEN56352.1Lipid A biosynthesis acyltransferase. (281 aa)
CEN56392.1D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase. (179 aa)
lpxCUDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (309 aa)
pyrC-2Dihydro-orotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (368 aa)
yraLPutative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (283 aa)
lppCPutative lipoprotein-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (546 aa)
yraNConserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0102 family. (113 aa)
yraODnaA initiator-associating factor for replication initiation; Function of homologous gene experimentally demonstrated in an other organism; factor. (196 aa)
CEN56587.1Transport-associated protein. (194 aa)
waaA3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (430 aa)
Your Current Organism:
Methylopumilus turicensis
NCBI taxonomy Id: 1581680
Other names: C. Methylopumilus turicensis, Candidatus Methylopumilus turicensis, Methylophilaceae bacterium MMS-10A-171
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