STRINGSTRING
ADY11953.1 ADY11953.1 ADY11959.1 ADY11959.1 ADY11969.1 ADY11969.1 ADY12306.1 ADY12306.1 ADY12307.1 ADY12307.1 accD accD accA accA ADY12467.1 ADY12467.1 purA purA pheS pheS ADY12490.1 ADY12490.1 nadE nadE ADY12659.1 ADY12659.1 guaA guaA ADY12694.1 ADY12694.1 ADY12819.1 ADY12819.1 ADY12953.1 ADY12953.1 ADY12970.1 ADY12970.1 ADY12972.1 ADY12972.1 atpA atpA atpB atpB atpD atpD asnA asnA ADY12999.1 ADY12999.1 argG argG metG metG ADY13030.1 ADY13030.1 ADY13087.1 ADY13087.1 ileS ileS ADY13142.1 ADY13142.1 hisS hisS ADY13170.1 ADY13170.1 ADY13273.1 ADY13273.1 atpB-2 atpB-2 atpA-2 atpA-2 ADY13277.1 ADY13277.1 valS valS cysS cysS ADY13577.1 ADY13577.1 ADY13580.1 ADY13580.1 asnS asnS ADY13599.1 ADY13599.1 ADY13600.1 ADY13600.1 ADY13609.1 ADY13609.1 ADY13612.1 ADY13612.1 ddl ddl serS serS ADY13621.1 ADY13621.1 glnS glnS tilS tilS ADY13765.1 ADY13765.1 tyrS tyrS glyQS glyQS gltX gltX argS argS birA birA alaS alaS ADY13968.1 ADY13968.1 purD purD purM purM purC purC lysS lysS ADY14384.1 ADY14384.1 ADY14387.1 ADY14387.1 ADY14388.1 ADY14388.1 ADY14417.1 ADY14417.1 ADY14612.1 ADY14612.1 thrS thrS ligA ligA ADY14749.1 ADY14749.1 aspS aspS proS proS leuS leuS pyrG pyrG
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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ADY11953.1PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp; KEGG: cth:Cthe_0202 L-glutamine synthetase. (426 aa)
ADY11959.1PFAM: Glutamine synthetase, catalytic domain; KEGG: cth:Cthe_0196 glutamine synthetase, catalytic region. (697 aa)
ADY11969.1TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; KEGG: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. (558 aa)
ADY12306.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (142 aa)
ADY12307.1Pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; KEGG: sta:STHERM_c08570 pyruvate carboxylase subunit A; SMART: Biotin carboxylase, C-terminal. (443 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (256 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (305 aa)
ADY12467.1KEGG: ssm:Spirs_0879 alanyl-tRNA synthetase, class IIc; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; SMART: Threonyl/alanyl tRNA synthetase, SAD. (394 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
pheSTIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 2, bacterial/archaeal; KEGG: ssm:Spirs_4136 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (512 aa)
ADY12490.1SMART: tRNA synthetase, B5; B3/B4 tRNA-binding domain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; KEGG: sta:STHERM_c21760 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase, B5. (565 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (635 aa)
ADY12659.1Lysine--tRNA ligase; KEGG: ssm:Spirs_3665 tRNA synthetase class II (D K and N); PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Belongs to the class-II aminoacyl-tRNA synthetase family. (330 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (517 aa)
ADY12694.1KEGG: ssm:Spirs_3695 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (640 aa)
ADY12819.1PFAM: Domain of unknown function DUF1508; KEGG: elm:ELI_4348 protein YegP. (128 aa)
ADY12953.1PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: dps:DP0137 hypothetical protein. (265 aa)
ADY12970.1PFAM: ATPase, F0/V0 complex, subunit C; KEGG: ssm:Spirs_3111 H+transporting two-sector ATPase C subunit; Belongs to the V-ATPase proteolipid subunit family. (116 aa)
ADY12972.1PFAM: ATPase, V1/A1 complex, subunit E; KEGG: mmg:MTBMA_c13440 A1AO ATPase, subunit E. (198 aa)
atpAV-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (592 aa)
atpBV-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (473 aa)
atpDV-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (232 aa)
asnAPFAM: Aspartate--ammonia ligase; TIGRFAM: Aspartate--ammonia ligase; HAMAP: Aspartate--ammonia ligase; KEGG: pdi:BDI_3717 asparagine synthetase AsnA. (344 aa)
ADY12999.1PFAM: Glutamine synthetase, catalytic domain; KEGG: cth:Cthe_0863 L-glutamine synthetase. (706 aa)
argGPFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: tma:TM1780 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)
metGMethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (741 aa)
ADY13030.1TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase; KEGG: sta:STHERM_c03310 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Mur ligase, central; Mur ligase, C-terminal; Belongs to the MurCDEF family. (441 aa)
ADY13087.1UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. (461 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1042 aa)
ADY13142.1TIGRFAM: Tryptophanyl-tRNA synthetase, class Ib; KEGG: cpy:Cphy_3480 tryptophanyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib. (330 aa)
hisSPFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: ssm:Spirs_1904 histidyl-tRNA synthetase. (444 aa)
ADY13170.1Protein of unknown function DUF214; KEGG: asu:Asuc_1431 LolC/E family lipoprotein releasing system, transmembrane protein; manually curated; PFAM: Domain of unknown function DUF214, ABC transporter permease. (389 aa)
ADY13273.1KEGG: ssm:Spirs_2457 V-type ATPase, D subunit; TIGRFAM: ATPase, V1/A1 complex, subunit D; PFAM: ATPase, V1/A1 complex, subunit D. (203 aa)
atpB-2V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (434 aa)
atpA-2V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (585 aa)
ADY13277.1KEGG: tde:TDE1381 V-type ATP synthase subunit E. (200 aa)
valSValyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (882 aa)
cysSTIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: sta:STHERM_c18260 hypothetical protein; PFAM: Cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa)
ADY13577.1KEGG: ssm:Spirs_2245 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (607 aa)
ADY13580.1KEGG: ssm:Spirs_1501 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (639 aa)
asnSPFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb; HAMAP: Asparaginyl-tRNA synthetase, class IIb; KEGG: ssm:Spirs_2248 asparaginyl-tRNA synthetase. (462 aa)
ADY13599.1KEGG: ssm:Spirs_2267 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (579 aa)
ADY13600.1FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; KEGG: ssm:Spirs_2271 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; Belongs to the folylpolyglutamate synthase family. (454 aa)
ADY13609.1KEGG: ssm:Spirs_2282 UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase, C-terminal; Mur ligase, central; Mur ligase, N-terminal. (486 aa)
ADY13612.1UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; KEGG: baf:BAPKO_0204 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; Belongs to the MurCDEF family. MurE subfamily. (493 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (360 aa)
serSSeryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (429 aa)
ADY13621.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (483 aa)
glnSPFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; TIGRFAM: Glutaminyl-tRNA synthetase, class Ic; HAMAP: Glutaminyl-tRNA synthetase, bacterial; KEGG: ssm:Spirs_1481 glutaminyl-tRNA synthetase. (562 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (484 aa)
ADY13765.1KEGG: ssm:Spirs_3134 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (569 aa)
tyrSTyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
glyQSglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (443 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (494 aa)
argSKEGG: ssm:Spirs_1801 arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic. (587 aa)
birAbiotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (324 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (598 aa)
ADY13968.1TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM; KEGG: mla:Mlab_0300 carbamoyl-phosphate synthase, large subunit; PFAM: AIR synthase-related protein, C-terminal. (1215 aa)
purDPhosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: phosphoribosylamine/glycine ligase; Belongs to the GARS family. (440 aa)
purMTIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal. (344 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: SAICAR synthetase; KEGG: phosphoribosylaminoimidazole-succinocarboxamide synthase. (237 aa)
lysSPFAM: Lysyl-tRNA synthetase, class Ic; TIGRFAM: Lysyl-tRNA synthetase, class I; HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; KEGG: ssm:Spirs_3699 lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (524 aa)
ADY14384.1KEGG: dbr:Deba_0210 D-alanine--D-alanine ligase domain protein. (310 aa)
ADY14387.1PFAM: D-alanine--D-alanine ligase, C-terminal; KEGG: sfu:Sfum_0713 D-alanine--D-alanine ligase domain-containing protein. (314 aa)
ADY14388.1D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (325 aa)
ADY14417.1PFAM: Protein of unknown function DUF1116; KEGG: protein of unknown function DUF1116. (1039 aa)
ADY14612.1Phosphoribosylamine/glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; KEGG: ssm:Spirs_3193 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C-domain. (418 aa)
thrSTIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Threonyl/alanyl tRNA synthetase, SAD; Anticodon-binding; KEGG: ssm:Spirs_3229 threonyl-tRNA synthetase; SMART: Threonyl/alanyl tRNA synthetase, SAD; Belongs to the class-II aminoacyl-tRNA synthetase family. (581 aa)
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (696 aa)
ADY14749.1SMART: Methylglyoxal synthase-like domain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; KEGG: sta:STHERM_c07390 carbamoyl-phosphate synthase large chain; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; Belongs to the CarB family. (1069 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa)
proSProlyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (588 aa)
leuSTIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; KEGG: ssm:Spirs_0283 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (842 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa)
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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