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| | ADY13621.1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (483 aa) |
| | ADY11871.1 | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (548 aa) |
| | ADY11902.1 | PFAM: Transaldolase; KEGG: ahe:Arch_0043 transaldolase. (349 aa) |
| | ADY11915.1 | KEGG: lsp:Bsph_1495 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase. (235 aa) |
| | ADY11947.1 | KEGG: tde:TDE0846 hypothetical protein. (729 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa) |
| | ADY11962.1 | KEGG: tde:TDE0009 hypothetical protein. (217 aa) |
| | ADY12111.1 | TIGRFAM: Phosphonopyruvate decarboxylase; KEGG: tde:TDE1414 phosphonopyruvate decarboxylase, putative; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (376 aa) |
| | ADY12112.1 | TIGRFAM: 2-aminoethylphosphonate aminotransferase; KEGG: tde:TDE1415 nucleotidyl transferase/aminotransferase, class V; PFAM: Aminotransferase, class V/Cysteine desulfurase. (609 aa) |
| | ADY12159.1 | PFAM: Inositol monophosphatase; KEGG: mca:MCA2609 inositol monophosphatase family protein. (264 aa) |
| | ADY12198.1 | Riboflavin kinase; KEGG: ere:EUBREC_1939 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; SMART: Riboflavin kinase. (230 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (256 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (305 aa) |
| | ADY12338.1 | PFAM: Transaldolase; KEGG: lsl:LSL_1888 fructose-6-phosphate aldolase. (225 aa) |
| | ADY12350.1 | PFAM: Transaldolase; KEGG: pak:HMPREF0675_3492 transaldolase. (340 aa) |
| | ADY12367.1 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa) |
| | ADY12390.1 | KEGG: dal:Dalk_0201 dCMP deaminase; PFAM: CMP/dCMP deaminase, zinc-binding. (161 aa) |
| | ADY12403.1 | KEGG: hdn:Hden_3452 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (322 aa) |
| | ADY12407.1 | KEGG: dhd:Dhaf_2635 triosephosphate isomerase; PFAM: Triosephosphate isomerase. (286 aa) |
| | ADY12411.1 | PFAM: Phosphoglucose isomerase (PGI); KEGG: gmc:GY4MC1_3102 glucose-6-phosphate isomerase. (426 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (391 aa) |
| | ADY12416.1 | TIGRFAM: Ketose-bisphosphate aldolase, class-II; KEGG: drt:Dret_1398 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-II. (385 aa) |
| | ADY12422.1 | Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: csh:Closa_2704 metallophosphoesterase. (432 aa) |
| | ADY12469.1 | KEGG: purB; adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal metazoa/fungi; Lyase 1, N-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (467 aa) |
| | ADY12477.1 | KEGG: cpe:CPE0924 metallo-beta-lactamase family protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (274 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa) |
| | ADY12485.1 | PFAM: Phosphoribosyltransferase; KEGG: ssm:Spirs_0876 phosphoribosyltransferase. (185 aa) |
| | ADY12486.1 | TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: toc:Toce_2097 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (185 aa) |
| | ADY12488.1 | Pyruvate dehydrogenase (acetyl-transferring); PFAM: Dehydrogenase, E1 component; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: fri:FraEuI1c_5335 dehydrogenase E1 component; SMART: Transketolase-like, pyrimidine-binding domain. (658 aa) |
| | ADY12531.1 | KEGG: ssm:Spirs_0330 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase. (396 aa) |
| | ADY12540.1 | KEGG: cpo:COPRO5265_0387 putative transketolase. (774 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa) |
| | ADY12595.1 | PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: ssm:Spirs_4117 4-diphosphocytidyl-2C-methyl-D-erythritolsynthas E. (270 aa) |
| | thyX | Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (273 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (635 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa) |
| | ADY12667.1 | KEGG: ssm:Spirs_3805 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (246 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (517 aa) |
| | ADY12719.1 | KEGG: ssm:Spirs_0464 transcriptional regulator, TraR/DksA family. (120 aa) |
| | ADY12729.1 | Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (511 aa) |
| | ADY12903.1 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (207 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa) |
| | ADY12951.1 | Hypothetical protein. (329 aa) |
| | ADY12970.1 | PFAM: ATPase, F0/V0 complex, subunit C; KEGG: ssm:Spirs_3111 H+transporting two-sector ATPase C subunit; Belongs to the V-ATPase proteolipid subunit family. (116 aa) |
| | ADY12972.1 | PFAM: ATPase, V1/A1 complex, subunit E; KEGG: mmg:MTBMA_c13440 A1AO ATPase, subunit E. (198 aa) |
| | atpA | V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (592 aa) |
| | atpB | V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (473 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (232 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (371 aa) |
| | ADY13047.1 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (194 aa) |
| | ADY13055.1 | KEGG: ssm:Spirs_1451 metal-dependent phosphohydrolase HD sub domain protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain. (383 aa) |
| | ADY13058.1 | Hypothetical protein; KEGG: deh:cbdb_A115 putative molybdopterin-guanine dinucleotide biosynthesis protein A. (155 aa) |
| | ADY13060.1 | PFAM: Inositol monophosphatase; KEGG: ssm:Spirs_3133 inositol monophosphatase. (268 aa) |
| | nadK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (287 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (177 aa) |
| | coaX | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (253 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa) |
| | ADY13147.1 | KEGG: has:Halsa_0822 glucose-6-phosphate 1-dehydrogenase; PFAM: Glucose-6-phosphate dehydrogenase, C-terminal; Glucose-6-phosphate dehydrogenase, NAD-binding. (457 aa) |
| | ADY13148.1 | KEGG: syx:SynWH7803_1296 6-phosphogluconolactonase. (210 aa) |
| | thiI | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (399 aa) |
| | ADY13178.1 | KEGG: ssm:Spirs_1940 thiamine pyrophosphokinase; TIGRFAM: Thiamin pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain. (210 aa) |
| | ADY13193.1 | KEGG: ssm:Spirs_2069 MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core. (278 aa) |
| | ADY13200.1 | RNA binding S1 domain protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (571 aa) |
| | cmk | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: ssm:Spirs_2055 cytidylate kinase; PFAM: Cytidylate kinase domain. (214 aa) |
| | ADY13207.1 | PFAM: Ribulose-phosphate 3-epimerase; manually curated; KEGG: tde:TDE2597 ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa) |
| | ADY13217.1 | PFAM: FAD synthetase; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF. (278 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (203 aa) |
| | folD | Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | ADY13253.1 | KEGG: ssm:Spirs_2435 phosphoribosyl transferase domain protein. (206 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | pgk | HAMAP: Phosphoglycerate kinase; KEGG: sta:STHERM_c09800 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase. (392 aa) |
| | ADY13261.1 | SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: ssm:Spirs_2445 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (347 aa) |
| | ADY13273.1 | KEGG: ssm:Spirs_2457 V-type ATPase, D subunit; TIGRFAM: ATPase, V1/A1 complex, subunit D; PFAM: ATPase, V1/A1 complex, subunit D. (203 aa) |
| | atpB-2 | V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (434 aa) |
| | atpA-2 | V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (585 aa) |
| | ADY13277.1 | KEGG: tde:TDE1381 V-type ATP synthase subunit E. (200 aa) |
| | ADY13280.1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (262 aa) |
| | ADY13292.1 | KEGG: elm:ELI_1158 IMP dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core. (502 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (209 aa) |
| | ADY13296.1 | KEGG: ssm:Spirs_1527 phosphoribosyl transferase domain-containing protein. (354 aa) |
| | ADY13304.1 | KEGG: putative acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase. (223 aa) |
| | ADY13328.1 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; KEGG: amt:Amet_3609 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; Belongs to the 5'-nucleotidase family. (594 aa) |
| | ADY13391.1 | PFAM: Lactonase, 7-bladed beta propeller; KEGG: ppm:PPSC2_c2269 6-phosphogluconolactonase. (332 aa) |
| | ADY13455.1 | 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; KEGG: ipo:Ilyop_0077 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (322 aa) |
| | ADY13457.1 | KEGG: ssm:Spirs_2352 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain. (419 aa) |
| | ADY13463.1 | PFAM: Phospholipid/glycerol acyltransferase; KEGG: ssm:Spirs_2368 acyltransferase. (377 aa) |
| | ADY13464.1 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (330 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (445 aa) |
| | ADY13510.1 | KEGG: ssm:Spirs_2755 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; SMART: Nucleoside diphosphate kinase. (400 aa) |
| | ADY13521.1 | Manually curated; PFAM: Phospholipid/glycerol acyltransferase; KEGG: syn:slr2060 hypothetical protein; SMART: Phospholipid/glycerol acyltransferase. (406 aa) |
| | ADY13522.1 | KEGG: ssm:Spirs_3802 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase. (224 aa) |
| | ADY13564.1 | KEGG: cpy:Cphy_3706 hypothetical protein. (213 aa) |
| | pfp-2 | Diphosphate/fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (552 aa) |
| | cmk-2 | KEGG: ssm:Spirs_2280 cytidylate kinase; TIGRFAM: Cytidylate kinase, putative; PFAM: Cytidylate kinase domain. (174 aa) |
| | ADY13635.1 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: amt:Amet_1529 glyoxalase/bleomycin resistance protein/dioxygenase. (120 aa) |
| | ADY13649.1 | KEGG: str:Sterm_0665 hypothetical protein. (122 aa) |
| | ADY13714.1 | TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; KEGG: ssm:Spirs_2588 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-II. (330 aa) |
| | araA | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (494 aa) |
| | nnrE | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (500 aa) |
| | ADY13751.1 | 5'-nucleotidase; KEGG: ppm:PPSC2_c1154 5-nucleotidase domain protein; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase. (920 aa) |
| | udk | TIGRFAM: Uridine kinase; HAMAP: Uridine kinase; KEGG: ssm:Spirs_2239 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase. (203 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (294 aa) |
| | ADY13784.1 | 4-hydroxythreonine-4-phosphate dehydrogenase; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; KEGG: fnu:FN0226 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; Belongs to the PdxA family. (342 aa) |
| | ADY13797.1 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. (194 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (211 aa) |
| | ADY13811.1 | TIGRFAM: Phosphate acetyltransferase; KEGG: ssm:Spirs_1512 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase. (333 aa) |
| | ADY13822.1 | KEGG: tde:TDE2107 dihydroorotase, putative. (348 aa) |
| | ADY13823.1 | KEGG: tde:TDE0982 dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; TIGRFAM: Dihydroorotate dehydrogenase, class 1; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; Oxidoreductase, FAD-binding domain; Oxidoreductase FAD/NAD(P)-binding; Belongs to the dihydroorotate dehydrogenase family. (577 aa) |
| | ADY13824.1 | SMART: Orotidine 5'-phosphate decarboxylase domain; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; KEGG: tde:TDE2110 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain. (288 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (232 aa) |
| | ADY13826.1 | TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; KEGG: tde:TDE0129 bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate carbamoyltransferase regulatory subunit, N-terminal; Aspartate carbamoyltransferase regulatory subunit, C-terminal. (534 aa) |
| | ADY13842.1 | PFAM: Inositol monophosphatase; KEGG: cts:Ctha_0496 inositol-phosphate phosphatase. (265 aa) |
| | ADY13849.1 | TIGRFAM: Phosphoribosyl pyrophosphokinase; KEGG: ssm:Spirs_0557 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. (430 aa) |
| | ADY13888.1 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (233 aa) |
| | ADY13893.1 | PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: dat:HRM2_15500 pyridoxamine kinase; Belongs to the pyridoxine kinase family. (274 aa) |
| | ADY13896.1 | Hexokinase; KEGG: ssm:Spirs_3985 hexokinase; PFAM: Hexokinase, N-terminal; Hexokinase, C-terminal. (436 aa) |
| | ADY13905.1 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (674 aa) |
| | ADY13910.1 | KEGG: meh:M301_0983 phospholipase D/transphosphatidylase; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase. (424 aa) |
| | ADY13912.1 | Dihydropyrimidinase; KEGG: ssm:Spirs_2735 dihydropyrimidinase; PFAM: Amidohydrolase 1. (466 aa) |
| | ADY13965.1 | PFAM: Oxidoreductase FAD/NAD(P)-binding; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; KEGG: ssm:Spirs_1640 oxidoreductase FAD/NAD(P)-binding domain protein. (282 aa) |
| | ADY13968.1 | TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM; KEGG: mla:Mlab_0300 carbamoyl-phosphate synthase, large subunit; PFAM: AIR synthase-related protein, C-terminal. (1215 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: phosphoribosylamine/glycine ligase; Belongs to the GARS family. (440 aa) |
| | ADY13970.1 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; KEGG: bvu:BVU_1693 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain. (385 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (431 aa) |
| | purM | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal. (344 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (466 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: SAICAR synthetase; KEGG: phosphoribosylaminoimidazole-succinocarboxamide synthase. (237 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (166 aa) |
| | ADY14031.1 | PFAM: Transaldolase; KEGG: sss:SSUSC84_0634 fructose-6-phosphate aldolase. (225 aa) |
| | ADY14045.1 | Dihydrolipoyllysine-residue acetyltransferase; KEGG: ckn:Calkro_1928 catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; E3 binding; Biotin/lipoyl attachment. (437 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa) |
| | dacA | Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (273 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa) |
| | ADY14129.1 | Hypothetical protein. (678 aa) |
| | ADY14290.1 | KEGG: tgr:Tgr7_2455 dihydrolipoyllysine-residue succinyltransferase; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding. (436 aa) |
| | ADY14291.1 | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa) |
| | ADY14333.1 | KEGG: msi:Msm_0690 helicase; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal. (984 aa) |
| | ADY14424.1 | Helix-turn-helix domain protein; SMART: Helix-turn-helix type 3; KEGG: gwc:GWCH70_1293 MazG nucleotide pyrophosphohydrolase. (182 aa) |
| | ADY14464.1 | PFAM: Inositol monophosphatase; KEGG: cbg:CbuG_0877 myo-inositol-1(or 4)-monophosphatase. (279 aa) |
| | ADY14474.1 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) |
| | ADY14533.1 | PFAM: NUDIX hydrolase domain; KEGG: ccb:Clocel_0501 NUDIX hydrolase. (169 aa) |
| | ADY14538.1 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: ssm:Spirs_1953 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (185 aa) |
| | ADY14567.1 | TIGRFAM: Pyruvate kinase; KEGG: hor:Hore_03220 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family. (477 aa) |
| | ADY14596.1 | SMART: ATPase, AAA+ type, core; KEGG: ssm:Spirs_3160 AAA ATPase. (561 aa) |
| | surE | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (266 aa) |
| | ADY14605.1 | CinA domain protein; TIGRFAM: CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; KEGG: ssm:Spirs_3180 competence/damage-inducible protein CinA; SMART: Molybdopterin binding; Belongs to the CinA family. (421 aa) |
| | ADY14612.1 | Phosphoribosylamine/glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; KEGG: ssm:Spirs_3193 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C-domain. (418 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (234 aa) |
| | ADY14692.1 | KEGG: ssm:Spirs_3225 CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (198 aa) |
| | ADY14702.1 | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (299 aa) |
| | pgi | KEGG: ssm:Spirs_3245 phosphoglucose isomerase (PGI); HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family. (523 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (446 aa) |
| | ADY14749.1 | SMART: Methylglyoxal synthase-like domain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; KEGG: sta:STHERM_c07390 carbamoyl-phosphate synthase large chain; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; Belongs to the CarB family. (1069 aa) |
| | ADY14767.1 | PFAM: Adenosine/AMP deaminase; TIGRFAM: Adenosine deaminase; HAMAP: Adenosine deaminase; KEGG: ssm:Spirs_0300 adenosine deaminase. (367 aa) |
| | ADY14787.1 | 4-hydroxythreonine-4-phosphate dehydrogenase; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; KEGG: dhd:Dhaf_1967 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; Belongs to the PdxA family. (335 aa) |
| | ADY14824.1 | Hypothetical protein; KEGG: ssm:Spirs_0330 phospholipid/glycerol acyltransferase. (439 aa) |
| | ADY14834.1 | PFAM: Thymidine kinase; KEGG: ssm:Spirs_0100 thymidine kinase; Belongs to the thymidine kinase family. (380 aa) |
| | deoC-2 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (221 aa) |
| | ADY14847.1 | Conserved hypothetical protein CHP00147; TIGRFAM: Diacylglycerol/lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; KEGG: ssm:Spirs_3801 diacylglycerol kinase catalytic region; SMART: Diacylglycerol kinase, catalytic domain. (309 aa) |
