STRINGSTRING
ADY12389.1 ADY12389.1 ADY12367.1 ADY12367.1 ADY12253.1 ADY12253.1 ADY12222.1 ADY12222.1 ADY12220.1 ADY12220.1 ADY12207.1 ADY12207.1 ADY12166.1 ADY12166.1 ADY12159.1 ADY12159.1 ADY12105.1 ADY12105.1 ADY11930.1 ADY11930.1 ADY11916.1 ADY11916.1 ADY11871.1 ADY11871.1 ADY14846.1 ADY14846.1 ADY14816.1 ADY14816.1 pfkA pfkA ADY14602.1 ADY14602.1 ADY14464.1 ADY14464.1 ADY14238.1 ADY14238.1 glpK glpK ADY14073.1 ADY14073.1 ADY13896.1 ADY13896.1 ADY13842.1 ADY13842.1 ADY13834.1 ADY13834.1 ADY13781.1 ADY13781.1 ADY13724.1 ADY13724.1 glgA glgA pfp-2 pfp-2 ADY13530.1 ADY13530.1 ADY13083.1 ADY13083.1 ADY13060.1 ADY13060.1 ADY13017.1 ADY13017.1 ADY12618.1 ADY12618.1 pfp pfp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADY12389.1PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: ssm:Spirs_0877 PfkB domain protein. (299 aa)
ADY12367.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
ADY12253.1KEGG: avn:Avin_27360 mannitol dehydrogenase; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal. (477 aa)
ADY12222.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa)
ADY12220.1Galactokinase; KEGG: bpb:bpr_I2414 GHMP kinase family protein; PFAM: GHMP kinase; GHMP kinase, C-terminal; Belongs to the GHMP kinase family. (394 aa)
ADY12207.1KEGG: hypothetical protein. (264 aa)
ADY12166.1KEGG: bbe:BBR47_56360 mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal. (394 aa)
ADY12159.1PFAM: Inositol monophosphatase; KEGG: mca:MCA2609 inositol monophosphatase family protein. (264 aa)
ADY12105.1LicD family protein; PFAM: LicD-like; KEGG: snp:SPAP_1298 LPS biosynthesis protein. (279 aa)
ADY11930.1Hypothetical protein. (67 aa)
ADY11916.1KEGG: kol:Kole_0990 myo-inositol catabolism IolB domain protein. (265 aa)
ADY11871.1Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (548 aa)
ADY14846.1KEGG: ssm:Spirs_0085 hypothetical protein. (474 aa)
ADY14816.1KEGG: cbe:Cbei_1833 altronate oxidoreductase; PFAM: Mannitol dehydrogenase, C-terminal; Bile acid:sodium symporter; Mannitol dehydrogenase, N-terminal. (816 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (446 aa)
ADY14602.1Galactokinase; KEGG: ssm:Spirs_3175 galactokinase; PFAM: GHMP kinase, C-terminal. (389 aa)
ADY14464.1PFAM: Inositol monophosphatase; KEGG: cbg:CbuG_0877 myo-inositol-1(or 4)-monophosphatase. (279 aa)
ADY14238.13-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: bth:BT_1713 putative acylneuraminate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; PFAM: Haloacid dehalogenase-like hydrolase. (173 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa)
ADY14073.1KEGG: cpy:Cphy_1062 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal. (534 aa)
ADY13896.1Hexokinase; KEGG: ssm:Spirs_3985 hexokinase; PFAM: Hexokinase, N-terminal; Hexokinase, C-terminal. (436 aa)
ADY13842.1PFAM: Inositol monophosphatase; KEGG: cts:Ctha_0496 inositol-phosphate phosphatase. (265 aa)
ADY13834.1Hypothetical protein; KEGG: chu:CHU_0232 antifreeze-related protein. (560 aa)
ADY13781.1KEGG: pmo:Pmob_0943 capsular polysaccharide synthesis enzyme CapC. (210 aa)
ADY13724.1Glucose-1-phosphate adenylyltransferase; KEGG: ssm:Spirs_2619 nucleotidyl transferase; PFAM: Nucleotidyl transferase. (431 aa)
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (484 aa)
pfp-2Diphosphate/fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (552 aa)
ADY13530.1KEGG: galK; galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase. (424 aa)
ADY13083.1PFAM: Glycoside hydrolase, family 57, N-terminal; Kinin peptide; Domain of unknown function DUF1957; KEGG: ssm:Spirs_1542 domain of unknown function DUF1957; Belongs to the glycosyl hydrolase 57 family. (531 aa)
ADY13060.1PFAM: Inositol monophosphatase; KEGG: ssm:Spirs_3133 inositol monophosphatase. (268 aa)
ADY13017.1KEGG: oih:OB2167 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. (409 aa)
ADY12618.1KEGG: tde:TDE0603 hypothetical protein. (302 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (391 aa)
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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