STRINGSTRING
ADY12867.1 ADY12867.1 ADY13060.1 ADY13060.1 ADY13069.1 ADY13069.1 ADY13081.1 ADY13081.1 dtd dtd ADY13207.1 ADY13207.1 ADY13280.1 ADY13280.1 ADY13286.1 ADY13286.1 ADY13324.1 ADY13324.1 ADY13447.1 ADY13447.1 ADY13529.1 ADY13529.1 araA araA ADY14449.1 ADY14449.1 ADY14416.1 ADY14416.1 ADY14414.1 ADY14414.1 ADY14413.1 ADY14413.1 ADY14389.1 ADY14389.1 murQ-2 murQ-2 anmK anmK ADY14284.1 ADY14284.1 ADY14283.1 ADY14283.1 ADY14248.1 ADY14248.1 glpK glpK ADY14083.1 ADY14083.1 uxuA uxuA ADY14070.1 ADY14070.1 fucI fucI rhaA rhaA ADY14040.1 ADY14040.1 ADY14034.1 ADY14034.1 gcvH gcvH ADY13914.1 ADY13914.1 ADY13913.1 ADY13913.1 ADY13892.1 ADY13892.1 ADY13860.1 ADY13860.1 ADY13842.1 ADY13842.1 gcvT gcvT ADY12349.1 ADY12349.1 ADY12365.1 ADY12365.1 ADY12367.1 ADY12367.1 ADY12405.1 ADY12405.1 ADY12539.1 ADY12539.1 ADY12550.1 ADY12550.1 ADY12553.1 ADY12553.1 ADY12571.1 ADY12571.1 ADY12645.1 ADY12645.1 ADY12699.1 ADY12699.1 nagB nagB ADY12720.1 ADY12720.1 ADY12757.1 ADY12757.1 uxaC uxaC ADY14817.1 ADY14817.1 ADY14682.1 ADY14682.1 ADY14513.1 ADY14513.1 ADY14464.1 ADY14464.1 ADY11871.1 ADY11871.1 ADY11915.1 ADY11915.1 ADY11916.1 ADY11916.1 ADY11930.1 ADY11930.1 ADY11979.1 ADY11979.1 ADY12015.1 ADY12015.1 ADY12021.1 ADY12021.1 ADY12030.1 ADY12030.1 ADY12034.1 ADY12034.1 murQ murQ ADY12159.1 ADY12159.1 ADY12180.1 ADY12180.1 ADY12188.1 ADY12188.1 ADY12201.1 ADY12201.1 ADY12334.1 ADY12334.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADY12867.1PFAM: Glucosamine/galactosamine-6-phosphate isomerase; KEGG: phe:Phep_0774 glucosamine-6-phosphate deaminase. (247 aa)
ADY13060.1PFAM: Inositol monophosphatase; KEGG: ssm:Spirs_3133 inositol monophosphatase. (268 aa)
ADY13069.1PFAM: L-fucose isomerase-like, C-terminal; KEGG: L-fucose isomerase-like protein. (490 aa)
ADY13081.1PFAM: Nucleoside phosphorylase domain; TIGRFAM: Purine nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase; KEGG: amt:Amet_4228 purine nucleoside phosphorylase. (235 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
ADY13207.1PFAM: Ribulose-phosphate 3-epimerase; manually curated; KEGG: tde:TDE2597 ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa)
ADY13280.1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (262 aa)
ADY13286.1Beta-lactamase domain protein; KEGG: ssm:Spirs_2469 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (202 aa)
ADY13324.1Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (637 aa)
ADY13447.1Esterase; PFAM: Putative esterase; KEGG: gym:GYMC10_5948 putative esterase. (253 aa)
ADY13529.1TIGRFAM: Galactose-1-phosphate uridyl transferase, class I; KEGG: gfo:GFO_2147 galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, N-terminal; Galactose-1-phosphate uridyl transferase, C-terminal. (350 aa)
araAL-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (494 aa)
ADY14449.1PFAM: Amidohydrolase 2; KEGG: ssa:SSA_2083 hypothetical protein. (299 aa)
ADY14416.1Cyclase family protein; PFAM: Putative cyclase; KEGG: hypothetical protein. (291 aa)
ADY14414.1Propanoyl-CoA C-acyltransferase; KEGG: clj:CLJU_c23630 putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
ADY14413.1PFAM: Domain of unknown function DUF35, OB-fold, C-terminal; KEGG: clj:CLJU_c23620 putative nucleic acid-binding protein. (127 aa)
ADY14389.1Lysine 2,3-aminomutase YodO family protein; TIGRFAM: Conserved hyprothetical protein CHP00238, KamA; KEGG: dat:HRM2_13250 KamA2; PFAM: Radical SAM. (421 aa)
murQ-2N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (311 aa)
anmKAnhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (409 aa)
ADY14284.1Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (330 aa)
ADY14283.1Beta-lactamase domain protein; PFAM: Beta-lactamase-like; KEGG: sli:Slin_6275 hypothetical protein. (281 aa)
ADY14248.1Beta-lactamase domain protein; KEGG: mac:MA2009 beta-lactamase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (226 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa)
ADY14083.1PFAM: L-fucose isomerase-like, C-terminal; KEGG: bpo:BP951000_1131 L-fucose isomerase-like protein. (438 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (358 aa)
ADY14070.1Glucosamine-6-phosphate deaminase; KEGG: sno:Snov_4298 glucosamine/galactosamine-6-phosphate isomerase; PFAM: Glucosamine/galactosamine-6-phosphate isomerase. (248 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (608 aa)
rhaAKEGG: csc:Csac_0876 L-rhamnose isomerase; PFAM: Rhamnose isomerase; Belongs to the rhamnose isomerase family. (416 aa)
ADY14040.1Alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; KEGG: csc:Csac_0869 alcohol dehydrogenase. (424 aa)
ADY14034.1L-iditol 2-dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; KEGG: sus:Acid_2859 alcohol dehydrogenase; SMART: Polyketide synthase, enoylreductase. (355 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
ADY13914.1Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (451 aa)
ADY13913.1KEGG: ssm:Spirs_2132 glycine cleavage system P-protein. (483 aa)
ADY13892.1PFAM: Nucleoside phosphorylase domain; KEGG: sta:STHERM_c12670 MTA/SAH nucleosidase. (222 aa)
ADY13860.1KEGG: ssm:Spirs_4169 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (253 aa)
ADY13842.1PFAM: Inositol monophosphatase; KEGG: cts:Ctha_0496 inositol-phosphate phosphatase. (265 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (372 aa)
ADY12349.1TIGRFAM: 2-hydroxy-3-oxopropionate reductase; KEGG: ssm:Spirs_0509 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding. (294 aa)
ADY12365.1L-iditol 2-dehydrogenase; KEGG: ssm:Spirs_3602 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal. (344 aa)
ADY12367.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
ADY12405.1KEGG: sss:SSUSC84_0197 glucosamine-6-phosphate isomerase; PFAM: Glucosamine/galactosamine-6-phosphate isomerase. (277 aa)
ADY12539.1HpcH/HpaI aldolase; PFAM: Aldehyde-lyase domain; KEGG: dhd:Dhaf_2073 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (251 aa)
ADY12550.12-dehydro-3-deoxyglucarate aldolase; KEGG: xbo:XBJ1_0873 putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, with PEP/pyruvate domain; PFAM: Aldehyde-lyase domain; Belongs to the HpcH/HpaI aldolase family. (259 aa)
ADY12553.1TIGRFAM: 2-hydroxy-3-oxopropionate reductase; KEGG: ssm:Spirs_0509 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding. (294 aa)
ADY12571.1KEGG: aoe:Clos_0355 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (230 aa)
ADY12645.1Lysine 2,3-aminomutase YodO family protein; TIGRFAM: Conserved hyprothetical protein CHP00238, KamA; KEGG: tte:TTE0723 lysine 2,3-aminomutase; PFAM: Radical SAM. (363 aa)
ADY12699.1UPF0597 protein yhaM; HAMAP: Uncharacterised protein family UPF0597; KEGG: ssm:Spirs_2717 protein of unknown function DUF1063; Belongs to the UPF0597 family. (424 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (270 aa)
ADY12720.1KEGG: ssm:Spirs_0466 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (215 aa)
ADY12757.1TIGRFAM: Purine nucleoside phosphorylase; KEGG: fma:FMG_0404 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase domain. (238 aa)
uxaCHAMAP: Uronate isomerase; KEGG: cow:Calow_1181 glucuronate isomerase; PFAM: Uronate isomerase. (467 aa)
ADY14817.1PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; SAF domain; KEGG: ttm:Tthe_2395 altronate dehydratase; SMART: SAF domain. (508 aa)
ADY14682.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (333 aa)
ADY14513.1KEGG: pcl:Pcal_1422 2-dehydro-3-deoxyglucarate aldolase; PFAM: Aldehyde-lyase domain; Belongs to the HpcH/HpaI aldolase family. (255 aa)
ADY14464.1PFAM: Inositol monophosphatase; KEGG: cbg:CbuG_0877 myo-inositol-1(or 4)-monophosphatase. (279 aa)
ADY11871.1Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (548 aa)
ADY11915.1KEGG: lsp:Bsph_1495 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase. (235 aa)
ADY11916.1KEGG: kol:Kole_0990 myo-inositol catabolism IolB domain protein. (265 aa)
ADY11930.1Hypothetical protein. (67 aa)
ADY11979.1KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like; Domain of unknown function DUF2437. (250 aa)
ADY12015.1KEGG: bfs:BF3383 hypothetical protein. (710 aa)
ADY12021.1TIGRFAM: 2-hydroxy-3-oxopropionate reductase; KEGG: ssm:Spirs_0509 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding. (294 aa)
ADY12030.1SMART: SAF domain; TIGRFAM: Galactarate dehydratase; KEGG: afn:Acfer_0082 galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; SAF domain. (502 aa)
ADY12034.1PFAM: Glucosamine/galactosamine-6-phosphate isomerase; KEGG: phe:Phep_0774 glucosamine-6-phosphate deaminase. (248 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (302 aa)
ADY12159.1PFAM: Inositol monophosphatase; KEGG: mca:MCA2609 inositol monophosphatase family protein. (264 aa)
ADY12180.1HpcH/HpaI aldolase; PFAM: Aldehyde-lyase domain; KEGG: cdl:CDR20291_1924 hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (257 aa)
ADY12188.1L-iditol 2-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; KEGG: amt:Amet_0554 alcohol dehydrogenase; SMART: Polyketide synthase, enoylreductase. (345 aa)
ADY12201.1HpcH/HpaI aldolase; PFAM: Aldehyde-lyase domain; KEGG: elm:ELI_1798 HpcH/HpaI aldolase/citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family. (279 aa)
ADY12334.1Beta-lactamase domain protein; SMART: Beta-lactamase-like; KEGG: csh:Closa_4139 hypothetical protein. (234 aa)
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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