(10 nodes) Translation protein, beta-barrel domain superfamily network (Sphaerochaeta globosa)

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Your Input:
	ADY12467.1	KEGG: ssm:Spirs_0879 alanyl-tRNA synthetase, class IIc; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; SMART: Threonyl/alanyl tRNA synthetase, SAD. (394 aa)
	ADY12991.1	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal. (613 aa)
	ADY13063.1	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal. (694 aa)
	fusA	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (676 aa)
	tuf	Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa)
	rimM	Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (168 aa)
	rplC	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (206 aa)
	infB	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (982 aa)
	lepA	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (605 aa)
	fusA-2	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (702 aa)

Your Current Organism:

Sphaerochaeta globosa

NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADY12991.1	ADY13063.1	SpiBuddy_1166	SpiBuddy_1238	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	0.509
ADY12991.1	fusA	SpiBuddy_1166	SpiBuddy_1240	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	0.509
ADY12991.1	fusA-2	SpiBuddy_1166	SpiBuddy_2273	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	0.509
ADY12991.1	infB	SpiBuddy_1166	SpiBuddy_1395	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.435
ADY12991.1	lepA	SpiBuddy_1166	SpiBuddy_1933	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.	0.408
ADY12991.1	rplC	SpiBuddy_1166	SpiBuddy_2850	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.518
ADY13063.1	ADY12991.1	SpiBuddy_1238	SpiBuddy_1166	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	0.509
ADY13063.1	fusA	SpiBuddy_1238	SpiBuddy_1240	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	0.495
ADY13063.1	infB	SpiBuddy_1238	SpiBuddy_1395	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.856
ADY13063.1	rimM	SpiBuddy_1238	SpiBuddy_1305	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.	0.709
ADY13063.1	rplC	SpiBuddy_1238	SpiBuddy_2850	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.975
ADY13063.1	tuf	SpiBuddy_1238	SpiBuddy_2852	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.960
fusA	ADY12991.1	SpiBuddy_1240	SpiBuddy_1166	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	0.509
fusA	ADY13063.1	SpiBuddy_1240	SpiBuddy_1238	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	TIGRFAM: Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; KEGG: ssm:Spirs_2536 small GTP-binding protein; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal.	0.495
fusA	infB	SpiBuddy_1240	SpiBuddy_1395	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.871
fusA	rimM	SpiBuddy_1240	SpiBuddy_1305	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.	0.722
fusA	rplC	SpiBuddy_1240	SpiBuddy_2850	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.972
fusA	tuf	SpiBuddy_1240	SpiBuddy_2852	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.941
fusA-2	ADY12991.1	SpiBuddy_2273	SpiBuddy_1166	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; KEGG: dsa:Desal_3190 GTP-binding protein TypA; SMART: Translation elongation factor EFG/EF2, C-terminal.	0.509
fusA-2	infB	SpiBuddy_2273	SpiBuddy_1395	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.828