STRINGSTRING
AEV28030.1 AEV28030.1 AEV28216.1 AEV28216.1 pgk pgk tpiA tpiA AEV28279.1 AEV28279.1 AEV28336.1 AEV28336.1 AEV28730.1 AEV28730.1 AEV28731.1 AEV28731.1 rbsK rbsK nagB nagB AEV28975.1 AEV28975.1 AEV29237.1 AEV29237.1 AEV29250.1 AEV29250.1 AEV29251.1 AEV29251.1 AEV29253.1 AEV29253.1 AEV29270.1 AEV29270.1 AEV29271.1 AEV29271.1 AEV29402.1 AEV29402.1 rbsK-2 rbsK-2 AEV29695.1 AEV29695.1 AEV29730.1 AEV29730.1 deoC deoC AEV29803.1 AEV29803.1 AEV29804.1 AEV29804.1 AEV29820.1 AEV29820.1 AEV29821.1 AEV29821.1 pfkA pfkA pgi pgi AEV29956.1 AEV29956.1 AEV30020.1 AEV30020.1 fda fda gpmA gpmA AEV30184.1 AEV30184.1 AEV30200.1 AEV30200.1 AEV30206.1 AEV30206.1 AEV30242.1 AEV30242.1 AEV30243.1 AEV30243.1 AEV30286.1 AEV30286.1 AEV30287.1 AEV30287.1 AEV30288.1 AEV30288.1 AEV30312.1 AEV30312.1 AEV30360.1 AEV30360.1 AEV30362.1 AEV30362.1 AEV30363.1 AEV30363.1 AEV30364.1 AEV30364.1 AEV30433.1 AEV30433.1 AEV30495.1 AEV30495.1 AEV30507.1 AEV30507.1 AEV30517.1 AEV30517.1 AEV30672.1 AEV30672.1 AEV30711.1 AEV30711.1 AEV30785.1 AEV30785.1 AEV30794.1 AEV30794.1 AEV30825.1 AEV30825.1 pdxT pdxT pdxS pdxS AEV30848.1 AEV30848.1 AEV30877.1 AEV30877.1 AEV30879.1 AEV30879.1 AEV30880.1 AEV30880.1 pfp pfp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEV28030.1DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme; PFAM: DeoC/LacD family aldolase. (270 aa)
AEV28216.1PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
pgkPFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (392 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
AEV28279.1PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
AEV28336.1Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. (505 aa)
AEV28730.16-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase. (247 aa)
AEV28731.1PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. (392 aa)
rbsKSugar kinase, ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (294 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (270 aa)
AEV28975.1PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I. (403 aa)
AEV29237.1Pentose-5-phosphate-3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. (228 aa)
AEV29250.1Transcriptional regulator; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. (280 aa)
AEV29251.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
AEV29253.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (344 aa)
AEV29270.1Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (312 aa)
AEV29271.1Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (280 aa)
AEV29402.1Phosphomannose isomerase. (617 aa)
rbsK-2Sugar kinase, ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
AEV29695.12,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (548 aa)
AEV29730.1PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. (394 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (221 aa)
AEV29803.1Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (296 aa)
AEV29804.1Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (305 aa)
AEV29820.1Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (277 aa)
AEV29821.1Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (315 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (444 aa)
pgiPFAM: Phosphoglucose isomerase; Belongs to the GPI family. (520 aa)
AEV29956.13-carboxymuconate cyclase; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme. (335 aa)
AEV30020.1Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase. (431 aa)
fdaPFAM: Fructose-bisphosphate aldolase class-I. (295 aa)
gpmAPhosphoglycerate mutase, BPG-dependent, family 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
AEV30184.1Phosphomannose isomerase. (596 aa)
AEV30200.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (662 aa)
AEV30206.1PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; manually curated. (383 aa)
AEV30242.16-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase. (223 aa)
AEV30243.1PFAM: Glucose-6-phosphate dehydrogenase, NAD binding domain; Glucose-6-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase. (450 aa)
AEV30286.1PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. (156 aa)
AEV30287.1Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (313 aa)
AEV30288.1Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (273 aa)
AEV30312.16-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase. (248 aa)
AEV30360.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (354 aa)
AEV30362.1PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family. (377 aa)
AEV30363.1PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family. (225 aa)
AEV30364.1Lysophospholipase L1-like esterase. (345 aa)
AEV30433.11-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family. (314 aa)
AEV30495.1Sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. (148 aa)
AEV30507.1PFAM: Hexokinase. (436 aa)
AEV30517.1PFAM: Phosphomethylpyrimidine kinase; Belongs to the pyridoxine kinase family. (280 aa)
AEV30672.1PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (438 aa)
AEV30711.1Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (570 aa)
AEV30785.1Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (445 aa)
AEV30794.1Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (323 aa)
AEV30825.1PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. (330 aa)
pdxTPyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (191 aa)
pdxSPyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (290 aa)
AEV30848.1Transcriptional regulator with HTH domain and aminotransferase domain; PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family. (465 aa)
AEV30877.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (314 aa)
AEV30879.1PFAM: Phosphoglycerate kinase. (429 aa)
AEV30880.1Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. (346 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (553 aa)
Your Current Organism:
Sphaerochaeta pleomorpha
NCBI taxonomy Id: 158190
Other names: S. pleomorpha str. Grapes, Sphaerochaeta pleomorpha str. Grapes, Sphaerochaeta sp. Grapes, Spirochaeta sp. Grapes
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