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AEV28414.1 AEV28414.1 dxr dxr AEV29452.1 AEV29452.1 AEV28518.1 AEV28518.1 AEV28568.1 AEV28568.1 AEV30104.1 AEV30104.1 AEV30116.1 AEV30116.1 AEV30137.1 AEV30137.1 AEV30139.1 AEV30139.1 AEV30243.1 AEV30243.1 AEV30285.1 AEV30285.1 AEV30309.1 AEV30309.1 AEV30354.1 AEV30354.1 AEV30360.1 AEV30360.1 AEV30437.1 AEV30437.1 AEV30744.1 AEV30744.1 AEV30840.1 AEV30840.1 AEV30877.1 AEV30877.1 AEV30923.1 AEV30923.1 AEV30924.1 AEV30924.1 AEV30071.1 AEV30071.1 AEV29794.1 AEV29794.1 AEV29766.1 AEV29766.1 AEV29564.1 AEV29564.1 aroE-2 aroE-2 AEV29395.1 AEV29395.1 AEV29379.1 AEV29379.1 AEV29365.1 AEV29365.1 AEV29289.1 AEV29289.1 AEV29283.1 AEV29283.1 AEV29273.1 AEV29273.1 aroE aroE AEV29253.1 AEV29253.1 AEV29251.1 AEV29251.1 AEV29233.1 AEV29233.1 AEV29199.1 AEV29199.1 AEV29176.1 AEV29176.1 hisD hisD AEV29071.1 AEV29071.1 AEV29030.1 AEV29030.1 ilvC ilvC leuB leuB AEV28851.1 AEV28851.1 AEV28670.1 AEV28670.1 AEV28657.1 AEV28657.1 murB murB AEV27990.1 AEV27990.1 AEV28028.1 AEV28028.1 AEV28184.1 AEV28184.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEV28414.1PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. (451 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (371 aa)
AEV29452.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (411 aa)
AEV28518.1PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (409 aa)
AEV28568.1PFAM: Iron-containing alcohol dehydrogenase. (395 aa)
AEV30104.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (304 aa)
AEV30116.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (426 aa)
AEV30137.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (331 aa)
AEV30139.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (343 aa)
AEV30243.1PFAM: Glucose-6-phosphate dehydrogenase, NAD binding domain; Glucose-6-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase. (450 aa)
AEV30285.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (393 aa)
AEV30309.1PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. (535 aa)
AEV30354.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (420 aa)
AEV30360.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (354 aa)
AEV30437.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain. (416 aa)
AEV30744.1PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (342 aa)
AEV30840.14-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (347 aa)
AEV30877.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (314 aa)
AEV30923.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (338 aa)
AEV30924.1PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. (487 aa)
AEV30071.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (331 aa)
AEV29794.1PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (335 aa)
AEV29766.1PFAM: Mannitol dehydrogenase Rossmann domain. (134 aa)
AEV29564.1PFAM: Ketopantoate reductase PanE/ApbA; TIGRFAM: 2-dehydropantoate 2-reductase. (319 aa)
aroE-2Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (293 aa)
AEV29395.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (372 aa)
AEV29379.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase. (430 aa)
AEV29365.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (374 aa)
AEV29289.1Glycerol dehydrogenase-like oxidoreductase; PFAM: 3-dehydroquinate synthase. (420 aa)
AEV29283.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (384 aa)
AEV29273.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (342 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (497 aa)
AEV29253.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (344 aa)
AEV29251.16-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
AEV29233.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (389 aa)
AEV29199.1PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (322 aa)
AEV29176.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (429 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
AEV29071.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (339 aa)
AEV29030.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (341 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa)
AEV28851.1Alcohol dehydrogenase, class IV; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (889 aa)
AEV28670.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (320 aa)
AEV28657.1Glycerol dehydrogenase-like oxidoreductase; PFAM: Iron-containing alcohol dehydrogenase. (365 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (305 aa)
AEV27990.1Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (294 aa)
AEV28028.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (342 aa)
AEV28184.1PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase. (502 aa)
Your Current Organism:
Sphaerochaeta pleomorpha
NCBI taxonomy Id: 158190
Other names: S. pleomorpha str. Grapes, Sphaerochaeta pleomorpha str. Grapes, Sphaerochaeta sp. Grapes, Spirochaeta sp. Grapes
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