(30 nodes) Mitochondrial genome maintenance network (Diaporthe helianthi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DHEL01_v211960	Uncharacterized protein. (139 aa)
	DHEL01_v211429	Chaperone DnaJ. (500 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (492 aa)
	DHEL01_v210851	Ketol-acid reductoisomerase; Belongs to the ketol-acid reductoisomerase family. (376 aa)
	DHEL01_v210540	ATP-dependent DNA helicase; Belongs to the helicase family. (894 aa)
	DHEL01_v209769	Ydc2-catalyt domain-containing protein. (388 aa)
	DHEL01_v209409	ATP-dependent DNA helicase; Belongs to the helicase family. (601 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (431 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (553 aa)
	DHEL01_v206255	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (927 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (546 aa)
	DHEL01_v205706	Uncharacterized protein. (158 aa)
	DHEL01_v205424	Mitochondrial ATP-dependent RNA helicase Suv3. (660 aa)
	DHEL01_v205171	HMG box protein. (307 aa)
	DHEL01_v204685	MutS domain V. (1010 aa)
	DHEL01_v204487	UV-damage endonuclease. (658 aa)
	DHEL01_v204579	DNA ligase. (883 aa)
	DHEL01_v204460	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (387 aa)
	DHEL01_v203151	RRM domain-containing protein. (853 aa)
	DHEL01_v201920	Mitochondrial genome maintenance protein MGM101. (327 aa)
	DHEL01_v201715	Uncharacterized protein. (346 aa)
	DHEL01_v201693	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1187 aa)
	DHEL01_v201149	DNA polymerase gamma. (1149 aa)
	DHEL01_v200930	Uncharacterized protein. (668 aa)
	PIF1-2	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (816 aa)
	DHEL01_v200125	Heat shock protein 78; Belongs to the ClpA/ClpB family. (717 aa)
	DHEL01_v200061	Uncharacterized protein. (141 aa)
	DHEL01_v212931	Uncharacterized protein. (173 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (523 aa)
	DHEL01_v212005	Uncharacterized protein. (231 aa)

Your Current Organism:

Diaporthe helianthi

NCBI taxonomy Id: 158607
Other names: CBS 592.81, D. helianthi, Phomopsis helianthi, Phomopsis sp. CBS 187.87

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHEL01_v200061	DHEL01_v201149	A0A2P5IGB2	A0A2P5ID62	Uncharacterized protein.	DNA polymerase gamma.	0.648
DHEL01_v200061	DHEL01_v201920	A0A2P5IGB2	A0A2P5IB73	Uncharacterized protein.	Mitochondrial genome maintenance protein MGM101.	0.563
DHEL01_v200061	DHEL01_v209409	A0A2P5IGB2	A0A2P5HPP7	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family.	0.404
DHEL01_v200061	DHEL01_v210540	A0A2P5IGB2	A0A2P5HLE3	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family.	0.404
DHEL01_v200061	PIF1	A0A2P5IGB2	A0A2P5HGU5	Uncharacterized protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.453
DHEL01_v200061	PIF1-2	A0A2P5IGB2	A0A2P5IG66	Uncharacterized protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.453
DHEL01_v200125	DHEL01_v211429	A0A2P5IG88	A0A2P5HIW4	Heat shock protein 78; Belongs to the ClpA/ClpB family.	Chaperone DnaJ.	0.773
DHEL01_v200930	DHEL01_v205706	A0A2P5IDU8	A0A2P5I059	Uncharacterized protein.	Uncharacterized protein.	0.547
DHEL01_v200930	MDM34	A0A2P5IDU8	A0A2P5HZN3	Uncharacterized protein.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.620
DHEL01_v201149	DHEL01_v200061	A0A2P5ID62	A0A2P5IGB2	DNA polymerase gamma.	Uncharacterized protein.	0.648
DHEL01_v201920	DHEL01_v200061	A0A2P5IB73	A0A2P5IGB2	Mitochondrial genome maintenance protein MGM101.	Uncharacterized protein.	0.563
DHEL01_v201920	DHEL01_v204685	A0A2P5IB73	A0A2P5I346	Mitochondrial genome maintenance protein MGM101.	MutS domain V.	0.498
DHEL01_v201920	MDM10	A0A2P5IB73	A0A2P5HVU5	Mitochondrial genome maintenance protein MGM101.	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.487
DHEL01_v201920	MDM34	A0A2P5IB73	A0A2P5HZN3	Mitochondrial genome maintenance protein MGM101.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.488
DHEL01_v201920	MMM1	A0A2P5IB73	A0A2P5HST2	Mitochondrial genome maintenance protein MGM101.	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	0.496
DHEL01_v204685	DHEL01_v201920	A0A2P5I346	A0A2P5IB73	MutS domain V.	Mitochondrial genome maintenance protein MGM101.	0.498
DHEL01_v205171	DHEL01_v210851	A0A2P5I1V0	A0A2P5HKJ4	HMG box protein.	Ketol-acid reductoisomerase; Belongs to the ketol-acid reductoisomerase family.	0.455
DHEL01_v205706	DHEL01_v200930	A0A2P5I059	A0A2P5IDU8	Uncharacterized protein.	Uncharacterized protein.	0.547
DHEL01_v205706	DHEL01_v211429	A0A2P5I059	A0A2P5HIW4	Uncharacterized protein.	Chaperone DnaJ.	0.437
DHEL01_v206255	DHEL01_v211960	A0A2P5HYM6	A0A2P5HHB2	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.436