STRINGSTRING
trmL trmL bioB bioB bioC bioC ubiG ubiG Daro_1475 Daro_1475 trmJ trmJ Daro_1913 Daro_1913 Daro_2021 Daro_2021 Daro_2309 Daro_2309 Daro_2340 Daro_2340 Daro_2341 Daro_2341 Daro_2380 Daro_2380 Daro_2396 Daro_2396 Daro_2893 Daro_2893 Daro_2895 Daro_2895 Daro_2896 Daro_2896 bioF bioF Daro_2898 Daro_2898 bioC-2 bioC-2 bioD bioD orn orn Daro_3002 Daro_3002 Daro_3003 Daro_3003 rsgA rsgA Daro_3178 Daro_3178 Daro_3180 Daro_3180 Daro_3181 Daro_3181 pcnB pcnB Daro_3184 Daro_3184 panB panB panC panC panD panD apaG apaG Daro_3485 Daro_3485 rsmA rsmA Daro_3660 Daro_3660 Daro_3661 Daro_3661 Daro_3662 Daro_3662 Daro_3663 Daro_3663 dusB dusB Daro_3666 Daro_3666 thiL thiL nadA nadA Daro_3854 Daro_3854 Daro_3856 Daro_3856 Daro_3857 Daro_3857 rdgC rdgC trmB trmB thiG thiG Daro_3862 Daro_3862 Daro_3863 Daro_3863 Daro_3864 Daro_3864 Daro_3865 Daro_3865 Daro_3867 Daro_3867 Daro_3868 Daro_3868 ubiB ubiB Daro_3900 Daro_3900 thiE thiE thiC thiC Daro_4116 Daro_4116 ubiE ubiE Daro_4118 Daro_4118 Daro_4120 Daro_4120 Daro_4121 Daro_4121 Daro_4122 Daro_4122 Daro_4141 Daro_4141 ttcA ttcA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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trmLRNA methyltransferase TrmH, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (154 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (327 aa)
bioCBiotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (297 aa)
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (232 aa)
Daro_1475Putative molybdenum utilization protein ModD; Belongs to the NadC/ModD family. (281 aa)
trmJRNA methyltransferase TrmH, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (254 aa)
Daro_1913Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (304 aa)
Daro_2021L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (525 aa)
Daro_2309Hypothetical protein. (666 aa)
Daro_2340Protein of unknown function UPF0125; Belongs to the UPF0125 (RnfH) family. (108 aa)
Daro_2341Cyclase/dehydrase. (147 aa)
Daro_2380Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family. (287 aa)
Daro_2396UBA/THIF-type NAD/FAD binding fold protein. (290 aa)
Daro_2893Protein of unknown function DUF328; Belongs to the UPF0246 family. (257 aa)
Daro_2895Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
Daro_2896Alpha/beta hydrolase fold protein. (304 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (387 aa)
Daro_2898Carboxylesterase BioH (pimeloyl-CoA synthesis). (237 aa)
bioC-2pimeloyl-CoA biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (262 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (221 aa)
ornExonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (184 aa)
Daro_3002Peptidase M48, Ste24p. (416 aa)
Daro_3003Hypothetical protein. (103 aa)
rsgAGTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (289 aa)
Daro_317823S rRNA m(1)G-745 methyltransferase. (283 aa)
Daro_3180Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. (230 aa)
Daro_3181HAD-superfamily hydrolase subfamily IB, PSPase-like protein:HAD-superfamily subfamily IB, PSPase-like protein. (222 aa)
pcnBPoly(A) polymerase, PcnB; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (447 aa)
Daro_3184Protein of unknown function DUF486. (120 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (272 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (274 aa)
panDAspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
apaGProtein of unknown function DUF525. (127 aa)
Daro_3485phosphatidyl-N-methylethanolamine N-methyltransferase. (197 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (255 aa)
Daro_3660Aminoglycoside phosphotransferase. (341 aa)
Daro_3661Nucleotidyl transferase. (223 aa)
Daro_3662Aminopeptidase P, Metallo peptidase, MEROPS family M24B. (432 aa)
Daro_36632-octaprenyl-6-methoxyphenol hydroxylase. (381 aa)
dusBtRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (337 aa)
Daro_3666Helix-turn-helix, Fis-type; Belongs to the transcriptional regulatory Fis family. (77 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (325 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (365 aa)
Daro_3854OmpA/MotB:Rickettsia 17 kDa surface antigen. (221 aa)
Daro_3856ABC transporter related protein. (559 aa)
Daro_3857SEC-C motif protein; Belongs to the UPF0225 family. (129 aa)
rdgCPutative exonuclease, RdgC; May be involved in recombination; Belongs to the RdgC family. (304 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (246 aa)
thiGThiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (260 aa)
Daro_3862Sulfur carrier protein ThiS. (67 aa)
Daro_3863Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
Daro_3864Twin-arginine translocation pathway signal. (218 aa)
Daro_3865Sporulation related protein. (209 aa)
Daro_3867Conserved hypothetical protein. (176 aa)
Daro_3868Diguanylate cyclase. (517 aa)
ubiB2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (506 aa)
Daro_3900Phosphomethylpyrimidine kinase. (291 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa)
thiCHydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (638 aa)
Daro_4116Protein of unknown function DUF1243. (189 aa)
ubiE2-octaprenyl-6-methoxy-1,4-benzoquinone methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (245 aa)
Daro_4118Protein of unknown function DUF971. (140 aa)
Daro_4120Histidine triad (HIT) protein. (143 aa)
Daro_4121FAD-binding PCMH-type domain-containing protein; Protein of unknown function DUF224, cysteine-rich region:FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal. (1291 aa)
Daro_4122Putative inner membrane protein. (141 aa)
Daro_4141Conserved hypothetical protein. (365 aa)
ttcAPP-loop; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (287 aa)
Your Current Organism:
Dechloromonas aromatica
NCBI taxonomy Id: 159087
Other names: D. aromatica RCB, Dechloromonas aromatica RCB, Dechloromonas aromatica str. RCB, Dechloromonas sp. RCB
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