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Daro_0830 Daro_0830 nadE nadE Daro_1313 Daro_1313 Daro_1318 Daro_1318 Daro_1367 Daro_1367 Daro_4149 Daro_4149 Daro_4100 Daro_4100 pyrB pyrB Daro_3862 Daro_3862 trmB trmB rpoZ rpoZ rpoH rpoH Daro_3751 Daro_3751 ribH ribH Daro_3721 Daro_3721 Daro_3629 Daro_3629 Daro_3521 Daro_3521 hisH hisH pfp pfp Daro_3150 Daro_3150 Daro_3142 Daro_3142 Daro_3088 Daro_3088 Daro_3083 Daro_3083 Daro_3077 Daro_3077 Daro_3076 Daro_3076 Daro_3075 Daro_3075 Daro_2950 Daro_2950 Daro_2945 Daro_2945 Daro_2944 Daro_2944 Daro_2885 Daro_2885 Daro_2859 Daro_2859 Daro_2858 Daro_2858 Daro_2833 Daro_2833 ppk ppk Daro_2729 Daro_2729 Daro_2694 Daro_2694 Daro_2634 Daro_2634 Daro_2590 Daro_2590 Daro_2573 Daro_2573 Daro_2555 Daro_2555 rpoS rpoS Daro_2513 Daro_2513 Daro_2507 Daro_2507 Daro_2504 Daro_2504 Daro_2291 Daro_2291 Daro_2285 Daro_2285 Daro_2280 Daro_2280 Daro_2231 Daro_2231 Daro_2196 Daro_2196 Daro_2124 Daro_2124 Daro_2022 Daro_2022 Daro_1990 Daro_1990 Daro_1982 Daro_1982 hscB hscB Daro_1952 Daro_1952 Daro_1951 Daro_1951 dnaE2 dnaE2 Daro_1938 Daro_1938 Daro_1856 Daro_1856 Daro_1832 Daro_1832 Daro_1797 Daro_1797 Daro_1784 Daro_1784 Daro_1689 Daro_1689 Daro_1620 Daro_1620 Daro_1619 Daro_1619 dnaQ dnaQ Daro_1520 Daro_1520 Daro_1514 Daro_1514 Daro_1448 Daro_1448 Daro_1381 Daro_1381 Daro_1432 Daro_1432 Daro_0002 Daro_0002 Daro_0266 Daro_0266 rpoB rpoB rpoC rpoC rpoA rpoA Daro_0521 Daro_0521 rpoD rpoD dnaG dnaG Daro_0542 Daro_0542 Daro_0559 Daro_0559 glgC glgC Daro_0636 Daro_0636 fliA fliA Daro_0789 Daro_0789 Daro_0795 Daro_0795 Daro_0797 Daro_0797
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Daro_0830Twin-arginine translocation pathway signal. (425 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (538 aa)
Daro_1313Hypothetical protein. (253 aa)
Daro_1318Binding-protein-dependent transport systems inner membrane component. (468 aa)
Daro_1367Regulatory protein, LuxR. (275 aa)
Daro_4149RNA polymerase, sigma 54 subunit, RpoN/SigL; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (489 aa)
Daro_4100Conserved hypothetical protein. (740 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (319 aa)
Daro_3862Sulfur carrier protein ThiS. (67 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (246 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (68 aa)
rpoHRNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (286 aa)
Daro_3751Conserved hypothetical protein. (643 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (160 aa)
Daro_3721Peptidase M16, C-terminal:Peptidase M16, N-terminal. (429 aa)
Daro_3629HAD-superfamily hydrolase subfamily IA, variant 3. (233 aa)
Daro_3521BRO, N-terminal. (199 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (419 aa)
Daro_3150RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
Daro_3142DNA replication and repair protein RadC; Belongs to the UPF0758 family. (226 aa)
Daro_3088SirA-like protein; Belongs to the sulfur carrier protein TusA family. (75 aa)
Daro_3083DNA polymerase III chi subunit, HolC. (140 aa)
Daro_3077Probable transmembrane protein. (127 aa)
Daro_3076RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
Daro_3075Acetolactate synthase, large subunit. (566 aa)
Daro_2950RNA polymerase, sigma subunit, SigZ; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)
Daro_2945Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (426 aa)
Daro_2944Sulfate adenylyltransferase subunit 2. (309 aa)
Daro_2885Putative methyltransferase. (226 aa)
Daro_28592-oxoglutarate dehydrogenase E1 component. (945 aa)
Daro_28582-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (407 aa)
Daro_2833Conserved hypothetical protein. (182 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (693 aa)
Daro_2729Molybdopterin synthase subunit MoaE. (150 aa)
Daro_2694Conserved hypothetical protein. (309 aa)
Daro_2634RNA polymerase, sigma subunit, SigZ; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
Daro_2590RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
Daro_2573Conserved hypothetical protein. (336 aa)
Daro_2555DNA repair protein RadC; Belongs to the UPF0758 family. (193 aa)
rpoSRNA polymerase, sigma 38 subunit, RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (309 aa)
Daro_2513BRO, N-terminal. (172 aa)
Daro_2507Hypothetical protein. (128 aa)
Daro_2504BRO family protein. (58 aa)
Daro_2291Conserved hypothetical protein. (336 aa)
Daro_2285Integrase, catalytic region. (275 aa)
Daro_2280Tetrahydromethanopterin S-methyltransferase, subunit A. (380 aa)
Daro_2231DNA repair protein RadC; Belongs to the UPF0758 family. (193 aa)
Daro_2196DNA polymerase III, delta prime subunit. (339 aa)
Daro_2124Sigma-70 region 2:Sigma-70 region 4; Belongs to the sigma-70 factor family. ECF subfamily. (226 aa)
Daro_2022RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
Daro_1990Sensor histidine kinase. (132 aa)
Daro_1982[SSU ribosomal protein S18P]-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (153 aa)
hscBCo-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (175 aa)
Daro_1952HesB/YadR/YfhF:Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. (107 aa)
Daro_1951FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (127 aa)
dnaE2Error-prone DNA polymerase, DnaE-like protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1027 aa)
Daro_1938Deoxyguanosinetriphosphate triphosphohydrolase. (448 aa)
Daro_1856Conserved hypothetical protein. (248 aa)
Daro_1832Sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)
Daro_1797Conserved hypothetical protein. (273 aa)
Daro_1784Molybdopterin synthase subunit MoaD. (82 aa)
Daro_1689precorrin-6Y C5,15-methyltransferase (decarboxylating). (428 aa)
Daro_1620Acetolactate synthase, large subunit. (556 aa)
Daro_1619Acetolactate synthase, small subunit. (103 aa)
dnaQDNA polymerase III, epsilon subunit:DNA polymerase 3, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (238 aa)
Daro_1520RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
Daro_1514Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. (298 aa)
Daro_1448NifQ. (190 aa)
Daro_1381DNA polymerase III, epsilon subunit. (204 aa)
Daro_1432Conserved hypothetical protein. (248 aa)
Daro_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (368 aa)
Daro_0266Conserved hypothetical protein. (249 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1427 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1403 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (324 aa)
Daro_0521Sigma-70 region 2:Sigma-70 region 4; Belongs to the sigma-70 factor family. ECF subfamily. (166 aa)
rpoDRNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (657 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (578 aa)
Daro_0542DNA polymerase III, delta subunit. (335 aa)
Daro_0559DNA polymerase III, alpha subunit. (1156 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (440 aa)
Daro_0636Conserved hypothetical protein. (83 aa)
fliARNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (248 aa)
Daro_0789BRO, N-terminal. (172 aa)
Daro_0795KilA, N-terminal. (106 aa)
Daro_0797BRO, N-terminal. (111 aa)
Your Current Organism:
Dechloromonas aromatica
NCBI taxonomy Id: 159087
Other names: D. aromatica RCB, Dechloromonas aromatica RCB, Dechloromonas aromatica str. RCB, Dechloromonas sp. RCB
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