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Daro_0252 Daro_0252 yidC yidC Daro_4182 Daro_4182 Daro_4176 Daro_4176 dsbD dsbD Daro_4165 Daro_4165 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB Daro_4098 Daro_4098 Daro_4093 Daro_4093 Daro_4084 Daro_4084 Daro_4070 Daro_4070 Daro_4058 Daro_4058 Daro_4055 Daro_4055 Daro_4045 Daro_4045 Daro_4044 Daro_4044 Daro_4031 Daro_4031 Daro_3994 Daro_3994 ccmC ccmC Daro_3992 Daro_3992 ccmA ccmA Daro_3982 Daro_3982 Daro_3945 Daro_3945 Daro_3903 Daro_3903 Daro_3828 Daro_3828 Daro_3764 Daro_3764 lolB lolB Daro_3692 Daro_3692 cysA cysA Daro_3566 Daro_3566 pstB pstB Daro_3563 Daro_3563 kup3 kup3 Daro_3545 Daro_3545 napA napA Daro_3514 Daro_3514 Daro_3513 Daro_3513 secA secA crcB crcB lptA lptA Daro_3417 Daro_3417 Daro_3395 Daro_3395 tatA tatA tatB tatB tatC tatC Daro_3347 Daro_3347 mscL mscL secF secF secD secD yajC yajC Daro_3236 Daro_3236 Daro_3235 Daro_3235 Daro_3216 Daro_3216 Daro_3210 Daro_3210 Daro_3209 Daro_3209 hppA hppA Daro_3201 Daro_3201 Daro_3191 Daro_3191 Daro_3169 Daro_3169 dsbB dsbB Daro_3130 Daro_3130 dctA dctA Daro_2863 Daro_2863 Daro_2840 Daro_2840 lolD lolD modC modC Daro_2783 Daro_2783 Daro_2771 Daro_2771 Daro_2770 Daro_2770 Daro_2738 Daro_2738 pcrB pcrB pcrC pcrC Daro_2579 Daro_2579 Daro_2359 Daro_2359 Daro_2358 Daro_2358 Daro_2161 Daro_2161 Daro_2152 Daro_2152 Daro_1936 Daro_1936 phnC phnC Daro_1824 Daro_1824 Daro_1762 Daro_1762 pqqB pqqB cbiM cbiM cbiN cbiN Daro_1694 Daro_1694 Daro_1582 Daro_1582 rnfD-2 rnfD-2 rnfC-2 rnfC-2 rnfB-2 rnfB-2 rnfA-2 rnfA-2 rnfE-2 rnfE-2 rnfG-2 rnfG-2 Daro_1483 Daro_1483 Daro_1471 Daro_1471 Daro_1470 Daro_1470 Daro_1457 Daro_1457 Daro_1451 Daro_1451 Daro_1437 Daro_1437 Daro_1436 Daro_1436 Daro_1319 Daro_1319 Daro_1318 Daro_1318 Daro_1317 Daro_1317 lolA lolA Daro_1198 Daro_1198 Daro_1197 Daro_1197 kup2 kup2 kdpA kdpA rnfA rnfA rnfB rnfB rnfC rnfC rnfD rnfD rnfG rnfG Daro_1165 Daro_1165 rnfE rnfE Daro_1115 Daro_1115 Daro_1114 Daro_1114 Daro_1112 Daro_1112 kdpB kdpB kdpC kdpC corA corA Daro_1080 Daro_1080 Daro_1068 Daro_1068 Daro_1043 Daro_1043 Daro_1015 Daro_1015 nuoN nuoN nuoK nuoK nuoD nuoD nuoC nuoC nuoB nuoB nuoA nuoA Daro_0948 Daro_0948 Daro_0908 Daro_0908 Daro_0831 Daro_0831 Daro_0810 Daro_0810 Daro_0809 Daro_0809 fliP fliP Daro_0744 Daro_0744 flhA flhA flhB flhB Daro_0716 Daro_0716 Daro_0713 Daro_0713 murJ murJ nhaA nhaA msrQ msrQ secB secB Daro_0612 Daro_0612 Daro_0598 Daro_0598 Daro_0571 Daro_0571 Daro_0498 Daro_0498 kup1 kup1 Daro_0480 Daro_0480 Daro_0450 Daro_0450 Daro_0446 Daro_0446 Daro_0367 Daro_0367 Daro_0366 Daro_0366 secY secY secE secE Daro_0272 Daro_0272 Daro_0271 Daro_0271 Daro_0251 Daro_0251 Daro_0228 Daro_0228 Daro_0214 Daro_0214 Daro_0201 Daro_0201 msbA msbA Daro_0080 Daro_0080 Daro_0054 Daro_0054 Daro_0049 Daro_0049
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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Daro_0252Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (358 aa)
yidCProtein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (547 aa)
Daro_4182Anaerobic c4-dicarboxylate membrane transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (441 aa)
Daro_4176Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (189 aa)
dsbDCytochrome c biogenesis protein, transmembrane region; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (586 aa)
Daro_4165ABC-2 type transporter, NodJ. (256 aa)
atpCATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (141 aa)
atpDATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (466 aa)
atpGATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (286 aa)
atpAATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (512 aa)
atpHATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa)
atpFATP synthase F0, subunit B; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa)
atpEATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (86 aa)
atpBATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (266 aa)
Daro_4098Branched-chain amino acid transport system ATP-binding protein; TC 3.A.1.4.-; TC 3.A.1.4.-; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (950 aa)
Daro_4093Outer membrane transport energization protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (228 aa)
Daro_4084Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (580 aa)
Daro_4070Phosphate ABC transporter substrate-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (351 aa)
Daro_4058Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (277 aa)
Daro_4055Cell division and transport-associated protein TolR; TC 2.C.1.2.1. (135 aa)
Daro_4045Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (315 aa)
Daro_4044Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
Daro_4031Transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (325 aa)
Daro_3994Heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (66 aa)
ccmCCytochrome c-type biogenesis protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (248 aa)
Daro_3992Cytochrome c-type biogenesis protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (222 aa)
ccmAHeme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (204 aa)
Daro_3982Rubredoxin-type Fe(Cys)4 protein; Belongs to the rubredoxin family. (66 aa)
Daro_3945High-affinity nickel-transporter; Belongs to the NiCoT transporter (TC 2.A.52) family. (269 aa)
Daro_3903Small multidrug resistance protein. (112 aa)
Daro_3828Hydrophobe/amphiphile efflux-1 HAE1. (1062 aa)
Daro_3764Cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (389 aa)
lolBOuter membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (190 aa)
Daro_3692Sulphate transport system permease protein 2:Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (291 aa)
cysASulphate transport system permease protein 1; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (355 aa)
Daro_3566Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (229 aa)
pstBPhosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (259 aa)
Daro_3563Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (311 aa)
kup3Potassium transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (626 aa)
Daro_3545OmpA-like transmembrane domain. (437 aa)
napAPeriplasmic nitrate reductase subunit NapA apoprotein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (837 aa)
Daro_3514Periplasmic nitrate reductase subunit NapB; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (146 aa)
Daro_3513Periplasmic nitrate reductase subunit NapC. (215 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (904 aa)
crcBCamphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (135 aa)
lptAOstA-like protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (200 aa)
Daro_3417Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (652 aa)
Daro_3395ABC-2 protein. (250 aa)
tatATwin-arginine translocation protein TatA/E; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (76 aa)
tatBSec-independent protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (120 aa)
tatCSec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (275 aa)
Daro_3347TrkA-N. (352 aa)
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (141 aa)
secFProtein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (314 aa)
secDSecD/SecF/SecDF export membrane protein:SecD export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (625 aa)
yajCProtein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (108 aa)
Daro_3236Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (349 aa)
Daro_3235Branched-chain amino acid transport system permease protein; TC 3.A.1.4.-; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (597 aa)
Daro_3216Type II and III secretion system protein:NolW-like:Secretin/TonB, short N-terminal. (667 aa)
Daro_3210MotA/TolQ/ExbB proton channel. (201 aa)
Daro_3209Biopolymer transport protein ExbD/TolR. (137 aa)
hppAInorganic H+ pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (688 aa)
Daro_3201Type I secretion membrane fusion protein, HlyD. (471 aa)
Daro_3191Nitric oxide reductase, NorB subunit apoprotein; Belongs to the heme-copper respiratory oxidase family. (458 aa)
Daro_3169Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (567 aa)
dsbBDisulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (165 aa)
Daro_3130Diheme cytochrome SoxA (sulfur oxidation). (271 aa)
dctASodium:dicarboxylate symporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (449 aa)
Daro_2863Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (594 aa)
Daro_2840Pyruvate:ferredoxin (flavodoxin) oxidoreductase. (1212 aa)
lolDLipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (225 aa)
modCMolybdate ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (359 aa)
Daro_2783Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (228 aa)
Daro_2771Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (288 aa)
Daro_2770Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (320 aa)
Daro_2738Sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (413 aa)
pcrBRespiratory nitrate reductase beta subunit; Component of the perchlorate reductase that catalyzes the reduction of perchlorate to chlorite and allows anaerobic growth on perchlorate as the sole electron acceptor. The beta subunit may be responsible for electron transfer to the catalytic alpha subunit PcrA (Probable). (333 aa)
pcrCCytochrome c-554 precursor; Component of the perchlorate reductase that catalyzes the reduction of perchlorate to chlorite and allows anaerobic growth on perchlorate as the sole electron acceptor. The gamma subunit may be responsible for electron transfer to the beta subunit PcrB (Probable). (236 aa)
Daro_2579NapC/NirT cytochrome c, N-terminal. (191 aa)
Daro_2359Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (292 aa)
Daro_2358Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (348 aa)
Daro_2161Hydrophobe/amphiphile efflux-1 HAE1. (1040 aa)
Daro_2152Binding-protein-dependent transport systems inner membrane component. (271 aa)
Daro_1936Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (548 aa)
phnCABC transporter related protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (275 aa)
Daro_1824Phosphonate uptake transporter. (518 aa)
Daro_1762L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (578 aa)
pqqBCoenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. (305 aa)
cbiMCobalamin (vitamin B12) biosynthesis CbiM protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (225 aa)
cbiNCobalt transport protein CbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (116 aa)
Daro_1694Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (291 aa)
Daro_1582NapC/NirT cytochrome c, N-terminal. (195 aa)
rnfD-2Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (357 aa)
rnfC-2Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (503 aa)
rnfB-2Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (177 aa)
rnfA-2Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa)
rnfE-2Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (224 aa)
rnfG-2Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (229 aa)
Daro_1483Flavodoxin, long chain; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (177 aa)
Daro_1471Cytochrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (401 aa)
Daro_1470Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (531 aa)
Daro_1457Flavodoxin, long chain; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (186 aa)
Daro_1451Beta-lactamase-like:Flavodoxin/nitric oxide synthase. (423 aa)
Daro_1437Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (525 aa)
Daro_1436Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (371 aa)
Daro_1319Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; Belongs to the ABC transporter superfamily. (658 aa)
Daro_1318Binding-protein-dependent transport systems inner membrane component. (468 aa)
Daro_1317Binding-protein-dependent transport systems inner membrane component. (325 aa)
lolAOuter membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (208 aa)
Daro_1198Binding-protein-dependent transport systems inner membrane component. (545 aa)
Daro_1197ABC transporter related protein; Belongs to the ABC transporter superfamily. (359 aa)
kup2Potassium transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (621 aa)
kdpAK+ transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (592 aa)
rnfAElectron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (194 aa)
rnfBElectron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (180 aa)
rnfCElectron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (570 aa)
rnfDElectron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (338 aa)
rnfGElectron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (222 aa)
Daro_1165Outer membrane efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (462 aa)
rnfEElectron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (230 aa)
Daro_1115Outer membrane transport energization protein ExbB; TC 2.C.1.1.1. (247 aa)
Daro_1114Outer membrane transport energization protein ExbD; TC 2.C.1.1.1. (141 aa)
Daro_1112Conserved hypothetical protein. (490 aa)
kdpBATPase, E1-E2 type:Potassium-translocating P-type ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (688 aa)
kdpCK+ transporting ATPase, KdpC subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (191 aa)
corAMagnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (321 aa)
Daro_1080Two-component system, OmpR family, sensor histidine kinase KdpD; ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor. (902 aa)
Daro_1068Small GTP-binding protein domain; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (649 aa)
Daro_1043Cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (320 aa)
Daro_1015Major facilitator superfamily MFS_1. (523 aa)
nuoNNADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (494 aa)
nuoKNADH dehydrogenase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (103 aa)
nuoDNADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (417 aa)
nuoCNADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (201 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (158 aa)
nuoANADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (124 aa)
Daro_0948Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (123 aa)
Daro_0908Branched-chain amino acid transport system ATP-binding protein; TC 3.A.1.4.-; TC 3.A.1.4.-; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (951 aa)
Daro_0831Nitrate transport permease. (312 aa)
Daro_0810Cytochrome b/b6, N-terminal:Cytochrome b/b6, C-terminal; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (433 aa)
Daro_0809Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (198 aa)
fliPFlagellar transport protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (248 aa)
Daro_0744MotA/TolQ/ExbB proton channel. (246 aa)
flhAFlagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (694 aa)
flhBFlagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (379 aa)
Daro_0716Cytochrome c oxidase cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (299 aa)
Daro_0713Cytochrome c oxidase cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. (475 aa)
murJVirulence factor MVIN-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (516 aa)
nhaASodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (389 aa)
msrQProtein of unknown function UPF0191; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit [...] (221 aa)
secBProtein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (152 aa)
Daro_0612Glutaredoxin, GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (86 aa)
Daro_0598Twin-arginine translocation pathway signal; Part of the tripartite ATP-independent periplasmic (TRAP) transport system. (362 aa)
Daro_0571Sulphate anion transporter. (563 aa)
Daro_0498TrkA-N. (563 aa)
kup1Potassium transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (630 aa)
Daro_0480Sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (433 aa)
Daro_0450Small multidrug resistance protein. (109 aa)
Daro_0446Indolepyruvate oxidoreductase subunit IorA; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (624 aa)
Daro_0367Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (291 aa)
Daro_0366Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (310 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (440 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (117 aa)
Daro_0272Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (353 aa)
Daro_0271Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (319 aa)
Daro_0251Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
Daro_0228FAD dependent oxidoreductase:Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (547 aa)
Daro_0214Type II and III secretion system protein:NolW-like:Secretin/TonB, short N-terminal. (715 aa)
Daro_0201ABC-type Mn2+/Zn2+ transport systems permease components-like protein. (254 aa)
msbALipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (585 aa)
Daro_0080Binding-protein-dependent transport systems inner membrane component. (318 aa)
Daro_0054Ammonium transporter; TC 1.A.11. (499 aa)
Daro_0049Drug resistance transporter Bcr/CflA subfamily. (400 aa)
Your Current Organism:
Dechloromonas aromatica
NCBI taxonomy Id: 159087
Other names: D. aromatica RCB, Dechloromonas aromatica RCB, Dechloromonas aromatica str. RCB, Dechloromonas sp. RCB
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