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Daro_0152 Daro_0152 Daro_0153 Daro_0153 Daro_0162 Daro_0162 Daro_0189 Daro_0189 Daro_0190 Daro_0190 Daro_0471 Daro_0471 Daro_0486 Daro_0486 gmhA gmhA Daro_0557 Daro_0557 lpxH lpxH Daro_1285 Daro_1285 hldD hldD lpxD lpxD lpxA lpxA lpxB lpxB kdsA kdsA kdsB kdsB lpxK lpxK Daro_3296 Daro_3296 Daro_3418 Daro_3418 Daro_3419 Daro_3419 lpxC lpxC Daro_3536 Daro_3536 Daro_3927 Daro_3927 Daro_3928 Daro_3928
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Daro_0152Lipopolysaccharide heptosyltransferase III, putative. (367 aa)
Daro_0153Glycosyl transferase, group 1. (381 aa)
Daro_0162Glycosyl transferase, family 9. (319 aa)
Daro_0189Lipid A biosynthesis acyltransferase. (280 aa)
Daro_0190Lipid A biosynthesis acyltransferase. (291 aa)
Daro_0471phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase. (555 aa)
Daro_0486Cytidyltransferase-related protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (162 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (196 aa)
Daro_0557Glycosyl hydrolase, BNR repeat. (375 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (242 aa)
Daro_1285D-alpha,beta-D-heptose 7-phosphate 1-kinase. (312 aa)
hldDADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (332 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (347 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (278 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (261 aa)
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (333 aa)
Daro_3296Lipopolysaccharide heptosyltransferase II. (337 aa)
Daro_3418KpsF/GutQ; Belongs to the SIS family. GutQ/KpsF subfamily. (332 aa)
Daro_3419HAD-superfamily hydrolase subfamily IIIA:Phosphatase kdsC. (175 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa)
Daro_3536D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. (183 aa)
Daro_3927Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (419 aa)
Daro_3928Lipopolysaccharide heptosyltransferase I. (317 aa)
Your Current Organism:
Dechloromonas aromatica
NCBI taxonomy Id: 159087
Other names: D. aromatica RCB, Dechloromonas aromatica RCB, Dechloromonas aromatica str. RCB, Dechloromonas sp. RCB
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