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Daro_0248 Daro_0248 Daro_0249 Daro_0249 Daro_0250 Daro_0250 Daro_0251 Daro_0251 Daro_0252 Daro_0252 Daro_0253 Daro_0253 Daro_0254 Daro_0254 Daro_0270 Daro_0270 Daro_0271 Daro_0271 Daro_0272 Daro_0272 Daro_0273 Daro_0273 Daro_0274 Daro_0274 secE secE secY secY Daro_0364 Daro_0364 Daro_0365 Daro_0365 Daro_0366 Daro_0366 Daro_0367 Daro_0367 Daro_0376 Daro_0376 Daro_0524 Daro_0524 Daro_0605 Daro_0605 secB secB ffh ffh Daro_0900 Daro_0900 Daro_0904 Daro_0904 Daro_0908 Daro_0908 Daro_0909 Daro_0909 Daro_0920 Daro_0920 Daro_0921 Daro_0921 Daro_0948 Daro_0948 Daro_1079 Daro_1079 Daro_1294 Daro_1294 Daro_1317 Daro_1317 Daro_1318 Daro_1318 Daro_1319 Daro_1319 Daro_1553 Daro_1553 Daro_1581 Daro_1581 Daro_1802 Daro_1802 Daro_1804 Daro_1804 Daro_1964 Daro_1964 Daro_2162 Daro_2162 Daro_2305 Daro_2305 Daro_2355 Daro_2355 Daro_2356 Daro_2356 Daro_2357 Daro_2357 Daro_2358 Daro_2358 Daro_2359 Daro_2359 Daro_2360 Daro_2360 Daro_2596 Daro_2596 Daro_2712 Daro_2712 Daro_2765 Daro_2765 Daro_2768 Daro_2768 Daro_2769 Daro_2769 Daro_2770 Daro_2770 Daro_2771 Daro_2771 Daro_2772 Daro_2772 Daro_2815 Daro_2815 Daro_2816 Daro_2816 Daro_2947 Daro_2947 hfq hfq Daro_3199 Daro_3199 Daro_3234 Daro_3234 Daro_3235 Daro_3235 Daro_3236 Daro_3236 Daro_3241 Daro_3241 yajC yajC Daro_3324 Daro_3324 Daro_3477 Daro_3477 trpE trpE secA secA Daro_3540 Daro_3540 Daro_3546 Daro_3546 Daro_3557 Daro_3557 ftsY ftsY Daro_4043 Daro_4043 Daro_4044 Daro_4044 Daro_4045 Daro_4045 Daro_4046 Daro_4046 Daro_4047 Daro_4047 Daro_4096 Daro_4096 Daro_4097 Daro_4097 Daro_4098 Daro_4098 Daro_4099 Daro_4099 Daro_4184 Daro_4184 yidC yidC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Daro_0248Cyclic nucleotide-binding protein. (224 aa)
Daro_0249AMP-dependent synthetase and ligase. (655 aa)
Daro_0250Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; TC 3.A.1.4.-. (260 aa)
Daro_0251Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
Daro_0252Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (358 aa)
Daro_0253Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (440 aa)
Daro_0254Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (291 aa)
Daro_0270Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (460 aa)
Daro_0271Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (319 aa)
Daro_0272Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (353 aa)
Daro_0273Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; TC 3.A.1.4.-. (253 aa)
Daro_0274Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (234 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (117 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (440 aa)
Daro_0364Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (437 aa)
Daro_0365Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; TC 3.A.1.4.-. (253 aa)
Daro_0366Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (310 aa)
Daro_0367Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (291 aa)
Daro_0376Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (381 aa)
Daro_0524Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (382 aa)
Daro_0605Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
secBProtein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (152 aa)
ffhSignal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] (455 aa)
Daro_0900Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (379 aa)
Daro_0904Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (377 aa)
Daro_0908Branched-chain amino acid transport system ATP-binding protein; TC 3.A.1.4.-; TC 3.A.1.4.-; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (951 aa)
Daro_0909Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (248 aa)
Daro_0920Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (382 aa)
Daro_0921Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (382 aa)
Daro_0948Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (123 aa)
Daro_1079Two component transcriptional regulator, winged helix family. (230 aa)
Daro_1294Cyclic nucleotide-binding:Bacterial regulatory protein, Crp. (220 aa)
Daro_1317Binding-protein-dependent transport systems inner membrane component. (325 aa)
Daro_1318Binding-protein-dependent transport systems inner membrane component. (468 aa)
Daro_1319Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; Belongs to the ABC transporter superfamily. (658 aa)
Daro_1553AMP-dependent synthetase and ligase. (553 aa)
Daro_1581Response regulator receiver:Transcriptional regulatory protein, C-terminal. (223 aa)
Daro_1802ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal. (482 aa)
Daro_1804Two component, sigma54 specific, transcriptional regulator, Fis family. (469 aa)
Daro_19643-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (341 aa)
Daro_2162RND efflux system, outer membrane lipoprotein, NodT. (475 aa)
Daro_2305Hypothetical protein. (212 aa)
Daro_2355AMP-dependent synthetase and ligase. (610 aa)
Daro_2356Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (269 aa)
Daro_2357Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (389 aa)
Daro_2358Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (348 aa)
Daro_2359Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (292 aa)
Daro_2360Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; TC 3.A.1.4.-. (278 aa)
Daro_2596Hypothetical protein. (212 aa)
Daro_2712Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (405 aa)
Daro_2765Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (408 aa)
Daro_2768Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (237 aa)
Daro_2769Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; TC 3.A.1.4.-. (257 aa)
Daro_2770Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (320 aa)
Daro_2771Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (288 aa)
Daro_2772Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (390 aa)
Daro_2815Response regulator receiver:Transcriptional regulatory protein, C-terminal. (218 aa)
Daro_2816ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal. (449 aa)
Daro_2947Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (367 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (78 aa)
Daro_3199VCBS protein. (4854 aa)
Daro_3234Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (248 aa)
Daro_3235Branched-chain amino acid transport system permease protein; TC 3.A.1.4.-; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (597 aa)
Daro_3236Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (349 aa)
Daro_3241Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (381 aa)
yajCProtein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (108 aa)
Daro_33243-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (359 aa)
Daro_3477Anthranilate synthase, component II. (190 aa)
trpEAnthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (491 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (904 aa)
Daro_3540Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (377 aa)
Daro_3546Cyclic nucleotide-binding protein. (124 aa)
Daro_3557Response regulator receiver:Transcriptional regulatory protein, C-terminal. (230 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (361 aa)
Daro_4043Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (388 aa)
Daro_4044Amino acid/amide ABC transporter membrane protein 1, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (304 aa)
Daro_4045Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (315 aa)
Daro_4046Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; TC 3.A.1.4.-. (251 aa)
Daro_4047Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (236 aa)
Daro_4096Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (379 aa)
Daro_4097Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (379 aa)
Daro_4098Branched-chain amino acid transport system ATP-binding protein; TC 3.A.1.4.-; TC 3.A.1.4.-; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family. (950 aa)
Daro_4099Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-. (251 aa)
Daro_4184Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-. (377 aa)
yidCProtein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (547 aa)
Your Current Organism:
Dechloromonas aromatica
NCBI taxonomy Id: 159087
Other names: D. aromatica RCB, Dechloromonas aromatica RCB, Dechloromonas aromatica str. RCB, Dechloromonas sp. RCB
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