STRINGSTRING
KHD19295.1 KHD19295.1 KHD22691.1 KHD22691.1 KHD22699.1 KHD22699.1 KHD22794.1 KHD22794.1 KHD22795.1 KHD22795.1 KHD22848.1 KHD22848.1 kdsB kdsB lpxK lpxK hldD hldD KHD21957.1 KHD21957.1 gmhA gmhA KHD22042.1 KHD22042.1 KHD22114.1 KHD22114.1 KHD21492.1 KHD21492.1 KHD21159.1 KHD21159.1 KHD20808.1 KHD20808.1 KHD20809.1 KHD20809.1 gmhA-2 gmhA-2 KHD20811.1 KHD20811.1 KHD20831.1 KHD20831.1 KHD20837.1 KHD20837.1 KHD20840.1 KHD20840.1 KHD20996.1 KHD20996.1 KHD20569.1 KHD20569.1 KHD20603.1 KHD20603.1 KHD20604.1 KHD20604.1 KHD20751.1 KHD20751.1 KHD20723.1 KHD20723.1 KHD20725.1 KHD20725.1 KHD20209.1 KHD20209.1 kdsA kdsA KHD19017.1 KHD19017.1 lpxB lpxB lpxA lpxA lpxD lpxD lpxH lpxH KHD18855.1 KHD18855.1 KHD18690.1 KHD18690.1 KHD18694.1 KHD18694.1 KHD18727.1 KHD18727.1 KHD18740.1 KHD18740.1 KHD18633.1 KHD18633.1 KHD18674.1 KHD18674.1 lpxC lpxC ubiB ubiB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KHD19295.1Deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family. (188 aa)
KHD22691.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (852 aa)
KHD22699.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KHD22794.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
KHD22795.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
KHD22848.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (267 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (354 aa)
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (330 aa)
KHD21957.1Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (195 aa)
KHD22042.1ADP-D-glycero-D-manno-heptose synthase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (161 aa)
KHD22114.1Arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily. (328 aa)
KHD21492.1Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
KHD21159.14-amino-4-deoxy-L-arabinose transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
KHD20808.1D,D-heptose 1,7-bisphosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
KHD20809.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
gmhA-2Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (198 aa)
KHD20811.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
KHD20831.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
KHD20837.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
KHD20840.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
KHD20996.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
KHD20569.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
KHD20603.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
KHD20604.1Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
KHD20751.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
KHD20723.13-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (452 aa)
KHD20725.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KHD20209.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (284 aa)
KHD19017.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (389 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (357 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (265 aa)
KHD18855.1Glycosyl transferase family A; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
KHD18690.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
KHD18694.1D,D-heptose 1,7-bisphosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
KHD18727.1Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
KHD18740.1ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
KHD18633.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
KHD18674.1SpoVR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
lpxCUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa)
ubiBUbiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (525 aa)
Your Current Organism:
Paraburkholderia sacchari
NCBI taxonomy Id: 159450
Other names: Burkholderia sacchari, Burkholderia sacchari Bramer et al. 2001, CCT 6771, CCUG 46043, CIP 107211, DSM 17165, IPT 101, LMG 19450, LMG:19450, P. sacchari, Paraburkholderia sacchari (Braner et al. 2001) Sawana et al. 2015
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