STRINGSTRING
LBAT_0013 LBAT_0013 LBAT_0040 LBAT_0040 LBAT_0041 LBAT_0041 LBAT_0042 LBAT_0042 LBAT_0043 LBAT_0043 LBAT_0053 LBAT_0053 LBAT_0056 LBAT_0056 proC proC LBAT_0066 LBAT_0066 LBAT_0067 LBAT_0067 LBAT_0105 LBAT_0105 LBAT_0137 LBAT_0137 LBAT_0141 LBAT_0141 LBAT_0150 LBAT_0150 ddl ddl LBAT_0164 LBAT_0164 LBAT_0165 LBAT_0165 LBAT_0181 LBAT_0181 LBAT_0201 LBAT_0201 LBAT_0202 LBAT_0202 LBAT_0203 LBAT_0203 LBAT_0209 LBAT_0209 LBAT_0213 LBAT_0213 gpmA gpmA plsY plsY LBAT_0226 LBAT_0226 LBAT_0242 LBAT_0242 metG metG glmU glmU murQ murQ prs prs LBAT_0270 LBAT_0270 LBAT_0279 LBAT_0279 LBAT_0280 LBAT_0280 coaD coaD coaA coaA pyrG pyrG murA murA LBAT_0301 LBAT_0301 LBAT_0303 LBAT_0303 LBAT_0306 LBAT_0306 mtnK mtnK LBAT_0309 LBAT_0309 LBAT_0310 LBAT_0310 xpt xpt guaA guaA glyA glyA murF murF LBAT_0333 LBAT_0333 ldh ldh adk adk gpmA-2 gpmA-2 LBAT_0400 LBAT_0400 LBAT_0413 LBAT_0413 gltX gltX LBAT_0421 LBAT_0421 LBAT_0422 LBAT_0422 tmk tmk LBAT_0447 LBAT_0447 LBAT_0454 LBAT_0454 zwf zwf LBAT_0464 LBAT_0464 murI murI LBAT_0476 LBAT_0476 LBAT_0490 LBAT_0490 LBAT_0493 LBAT_0493 metK metK LBAT_0517 LBAT_0517 LBAT_0521 LBAT_0521 LBAT_0523 LBAT_0523 murC murC coaE coaE nadD nadD LBAT_0559 LBAT_0559 LBAT_0566 LBAT_0566 LBAT_0567 LBAT_0567 LBAT_0571 LBAT_0571 miaA miaA glnA glnA LBAT_0589 LBAT_0589 LBAT_0590 LBAT_0590 pyrE pyrE pyrF pyrF LBAT_0593 LBAT_0593 pyrR pyrR pyrB pyrB pyrC pyrC carA carA LBAT_0598 LBAT_0598 LBAT_0599 LBAT_0599 fabZ fabZ fabH fabH acpP acpP LBAT_0612 LBAT_0612 LBAT_0613 LBAT_0613 fabF fabF accB accB LBAT_0616 LBAT_0616 LBAT_0617 LBAT_0617 accD accD LBAT_0619 LBAT_0619 LBAT_0620 LBAT_0620 LBAT_0622 LBAT_0622 folD folD LBAT_0638 LBAT_0638 gmk gmk rsgA rsgA rpe rpe LBAT_0653 LBAT_0653 plsX plsX acpP-2 acpP-2 LBAT_0688 LBAT_0688 LBAT_0690 LBAT_0690 pyrH pyrH LBAT_0699 LBAT_0699 LBAT_0710 LBAT_0710 apt apt LBAT_0719 LBAT_0719 LBAT_0720 LBAT_0720 eno eno thyA thyA LBAT_0749 LBAT_0749 deoC deoC LBAT_0763 LBAT_0763 LBAT_0772 LBAT_0772 glpK glpK LBAT_0787 LBAT_0787 LBAT_0788 LBAT_0788 LBAT_0789 LBAT_0789 LBAT_0809 LBAT_0809 fumC fumC LBAT_0816 LBAT_0816 ldh-2 ldh-2 LBAT_0829 LBAT_0829 LBAT_0833 LBAT_0833 LBAT_0864 LBAT_0864 fni fni LBAT_0871 LBAT_0871 LBAT_0872 LBAT_0872 LBAT_0873 LBAT_0873 LBAT_0881 LBAT_0881 fhs fhs LBAT_0892 LBAT_0892 LBAT_0893 LBAT_0893 plsY-2 plsY-2 cmk cmk LBAT_0944 LBAT_0944 pfkA pfkA LBAT_0948 LBAT_0948 LBAT_0958 LBAT_0958 coaBC coaBC LBAT_0965 LBAT_0965 LBAT_0972 LBAT_0972 coaD-2 coaD-2 LBAT_1009 LBAT_1009 LBAT_1010 LBAT_1010 LBAT_1012 LBAT_1012 murG murG murD murD mraY mraY LBAT_1038 LBAT_1038 thiI thiI LBAT_1041 LBAT_1041 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB upp upp tdk tdk LBAT_1067 LBAT_1067 pgi pgi LBAT_1074 LBAT_1074 LBAT_1080 LBAT_1080 LBAT_1081 LBAT_1081 ackA ackA LBAT_1103 LBAT_1103 mtlD mtlD LBAT_1120 LBAT_1120 LBAT_1121 LBAT_1121 glmS glmS glmM glmM murB murB LBAT_1130 LBAT_1130 tpiA tpiA pgk pgk gap gap LBAT_1151 LBAT_1151 LBAT_1163 LBAT_1163 LBAT_1185 LBAT_1185 LBAT_1187 LBAT_1187 LBAT_1196 LBAT_1196 LBAT_1198 LBAT_1198 LBAT_1201 LBAT_1201 nadK nadK LBAT_1205 LBAT_1205 LBAT_1226 LBAT_1226 LBAT_1229 LBAT_1229 LBAT_1230 LBAT_1230 LBAT_1235 LBAT_1235 LBAT_1240 LBAT_1240 LBAT_1245 LBAT_1245 rpiA rpiA rbsK rbsK LBAT_1260 LBAT_1260 LBAT_1263 LBAT_1263 udk udk pyrR-2 pyrR-2 LBAT_1271 LBAT_1271 LBAT_1304 LBAT_1304 gatB gatB gatA gatA gatC gatC nadE nadE LBAT_1318 LBAT_1318 LBAT_1325 LBAT_1325 LBAT_1328 LBAT_1328 LBAT_1345 LBAT_1345 LBAT_1346 LBAT_1346 LBAT_1353 LBAT_1353 LBAT_1356 LBAT_1356 LBAT_1357 LBAT_1357 LBAT_1358 LBAT_1358 LBAT_1363 LBAT_1363 LBAT_1384 LBAT_1384 coaA-2 coaA-2 LBAT_1395 LBAT_1395 tal tal LBAT_1397 LBAT_1397 LBAT_1415 LBAT_1415 LBAT_1437 LBAT_1437 pfkB pfkB LBAT_1444 LBAT_1444 LBAT_1462 LBAT_1462 LBAT_1463 LBAT_1463 LBAT_1481 LBAT_1481 LBAT_1483 LBAT_1483 LBAT_1495 LBAT_1495 LBAT_1506 LBAT_1506 LBAT_1507 LBAT_1507 LBAT_1508 LBAT_1508 LBAT_1513 LBAT_1513 glpK-2 glpK-2 LBAT_1525 LBAT_1525 LBAT_1530 LBAT_1530 thiM thiM LBAT_1537 LBAT_1537 LBAT_1542 LBAT_1542 LBAT_1543 LBAT_1543 purA purA guaC guaC asnA asnA dltC dltC dltA dltA LBAT_1573 LBAT_1573 nagB nagB LBAT_1640 LBAT_1640 LBAT_1649 LBAT_1649 LBAT_1650 LBAT_1650
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
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LBAT_0013Fructokinase. (293 aa)
LBAT_0040dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (345 aa)
LBAT_0041Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa)
LBAT_0042dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (202 aa)
LBAT_0043dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (328 aa)
LBAT_0053Cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (180 aa)
LBAT_0056Ribonucleoside triphosphate reductase. (744 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (254 aa)
LBAT_0066Alpha,alpha-phosphotrehalase. (554 aa)
LBAT_0067D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)
LBAT_0105Glutathione S-transferase; Belongs to the GST superfamily. (211 aa)
LBAT_0137NAD-dependent deacetylase. (234 aa)
LBAT_0141Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (485 aa)
LBAT_0150Ribose-phosphate pyrophosphokinase. (328 aa)
ddlD-alanyl-alanine synthase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (361 aa)
LBAT_0164N-acetylglucosamine-6-phosphate deacetylase. (386 aa)
LBAT_0165Nucleoside 2-deoxyribosyltransferase. (158 aa)
LBAT_0181Asparagine synthase. (649 aa)
LBAT_0201Conserved hypothetical protein. (123 aa)
LBAT_0202Dihydroxyacetone kinase L subunit. (194 aa)
LBAT_0203Dihydroxyacetone kinase DhaK subunit. (331 aa)
LBAT_0209Truncated glycerol dehydrogenase. (229 aa)
LBAT_0213Oxidoreductase. (321 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa)
plsYConserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (194 aa)
LBAT_0226Inosine-5'-monophosphate dehydrogenase. (380 aa)
LBAT_0242dCMP deaminase. (159 aa)
metGmethionyl-tRNA synthase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (658 aa)
glmUUDP-N-acetylglucosamine diphosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (461 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (298 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa)
LBAT_0270Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family. (293 aa)
LBAT_0279Enoyl-[acyl-carrier-protein] reductase. (312 aa)
LBAT_0280Propionate CoA-transferase. (363 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
coaAPantothenate kinase. (303 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (541 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (431 aa)
LBAT_0301PTS system galactitol-specific IIA component. (157 aa)
LBAT_0303PTS system galactitol-specific IIC component. (530 aa)
LBAT_0306Aldolase. (172 aa)
mtnK5-methylthioribose kinase. (408 aa)
LBAT_0309Translation initiation factor subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (350 aa)
LBAT_0310L-fuculose phosphate aldolase. (216 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (192 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (517 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa)
LBAT_0333Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (376 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (323 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa)
gpmA-2Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (225 aa)
LBAT_0400Malate dehydrogenase. (540 aa)
LBAT_0413dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (185 aa)
gltXglutamyl-tRNA synthase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (499 aa)
LBAT_0421Gluconate kinase. (498 aa)
LBAT_04221-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (560 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (215 aa)
LBAT_0447acyl-ACP thioesterase. (217 aa)
LBAT_0454Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (485 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (483 aa)
LBAT_0464Conserved hypothetical protein. (318 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (269 aa)
LBAT_0476Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (205 aa)
LBAT_0490Glycosyltransferase. (390 aa)
LBAT_0493Phosphoglycerol transferase. (687 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
LBAT_0517D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (433 aa)
LBAT_0521Fructose-bisphosphate aldolase. (294 aa)
LBAT_0523Penicillin-binding protein. (685 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (438 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
nadDNicotinate-nucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (213 aa)
LBAT_0559Acylphosphatase. (107 aa)
LBAT_0566L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily. (303 aa)
LBAT_0567N-acetylglucosamine kinase. (306 aa)
LBAT_05715-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (190 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa)
glnAGlutamine synthase. (445 aa)
LBAT_0589Carboxymuconolactone decarboxylase. (124 aa)
LBAT_0590Deacetylase. (238 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (212 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (235 aa)
LBAT_0593Dihydroorotate dehydrogenase 1B. (221 aa)
pyrRUracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (180 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (332 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (424 aa)
carACarbamoyl phosphate synthase small subunit; Belongs to the CarA family. (362 aa)
LBAT_0598Truncated carbamoyl phosphate synthase large subunit; Belongs to the CarB family. (250 aa)
LBAT_0599Truncated carbamoyl phosphate synthase large subunit; Belongs to the CarB family. (798 aa)
fabZ3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (148 aa)
fabH3-oxoacyl-[acyl carrier protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (90 aa)
LBAT_0612[acyl-carrier-protein] S-malonyltransferase. (305 aa)
LBAT_06133-oxoacyl-[acyl-carrier protein] reductase. (242 aa)
fabFBeta-ketoacyl-[acyl-carrier protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (409 aa)
accBacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa)
LBAT_0616(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase. (138 aa)
LBAT_0617acetyl-CoA carboxylase. (457 aa)
accDacetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (274 aa)
LBAT_0619acetyl-CoA carboxylase alpha subunit. (256 aa)
LBAT_0620Enoyl-[acyl-carrier-protein] reductase. (252 aa)
LBAT_0622biotin-[acetyl-CoA-carboxylase] ligase. (261 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa)
LBAT_0638Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (289 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
rsgARibosome small subunit-dependent GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (297 aa)
rpeRibulose-phosphate 3-epimerase. (219 aa)
LBAT_0653Thiamine pyrophosphokinase. (228 aa)
plsXGlycerol-3-phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (334 aa)
acpP-2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (80 aa)
LBAT_0688Glycolate oxidase. (469 aa)
LBAT_06901-acyl-sn-glycerol-3-phosphate acyltransferase. (204 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
LBAT_0699Phosphatidate cytidylyltransferase. (265 aa)
LBAT_0710Riboflavin kinase; Belongs to the ribF family. (311 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (175 aa)
LBAT_0719Cardiolipin synthase Cls; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (494 aa)
LBAT_0720Cation-transporting ATPase. (757 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (318 aa)
LBAT_0749Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (174 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (237 aa)
LBAT_0763Truncated cadmium-/manganese-transporting P-type ATPase. (513 aa)
LBAT_0772Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (793 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (501 aa)
LBAT_0787PTS system IIA component. (150 aa)
LBAT_0788PTS system IIB component. (107 aa)
LBAT_0789PTS system IIC component. (304 aa)
LBAT_0809Succinyl-diaminopimelate desuccinylase. (388 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
LBAT_0816Fumarate reductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (462 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (309 aa)
LBAT_0829GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (746 aa)
LBAT_0833Aromatic amino acid aminotransferase. (394 aa)
LBAT_0864Sugar-phosphatase. (262 aa)
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (322 aa)
LBAT_0871Phosphomevalonate kinase. (334 aa)
LBAT_0872Diphosphomevalonate decarboxylase. (320 aa)
LBAT_0873Mevalonate kinase. (302 aa)
LBAT_0881Penicillin binding protein 1A. (782 aa)
fhsFormate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (558 aa)
LBAT_0892Carbamoyl phosphate synthase small subunit. (351 aa)
LBAT_0893Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. (1058 aa)
plsY-2Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (214 aa)
cmkCytidylate kinase. (224 aa)
LBAT_0944Pyruvate kinase; Belongs to the pyruvate kinase family. (589 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
LBAT_09482',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (518 aa)
LBAT_0958Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
coaBCPantothenate metabolism flavoprotein-like protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (397 aa)
LBAT_0965Maltose phosphorylase. (727 aa)
LBAT_0972Nucleoside hydrolase. (309 aa)
coaD-2Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)
LBAT_1009Cysteine desulfurase. (385 aa)
LBAT_1010Nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (231 aa)
LBAT_1012ADP-ribose pyrophosphatase. (190 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (368 aa)
murDUDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (459 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (319 aa)
LBAT_1038Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (425 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (405 aa)
LBAT_1041Aminotransferase. (385 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (145 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (479 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (320 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (503 aa)
atpHF0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (182 aa)
atpFF0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (168 aa)
atpEF0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (237 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
tdkThymidine kinase. (199 aa)
LBAT_1067UDP-N-acetylmuramyl tripeptide synthase. (450 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa)
LBAT_1074Alkaline phosphatase. (730 aa)
LBAT_1080Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (322 aa)
LBAT_1081Aminotransferase. (387 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
LBAT_1103Glycerate kinase; Belongs to the glycerate kinase type-1 family. (385 aa)
mtlDMannitol-1-phosphate 5-dehydrogenase. (389 aa)
LBAT_1120PTS system mannitol-specific IIA component. (148 aa)
LBAT_1121PTS system mannitol-specific IIBC components. (594 aa)
glmSGlutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (603 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (450 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (297 aa)
LBAT_1130Phosphate acetyltransferase. (327 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
LBAT_1151Phosphoglucomutase. (574 aa)
LBAT_1163Undecaprenyl-phosphaten-acetyl- glucosaminyltransfera se. (386 aa)
LBAT_1185CDP-diacylglycerol- phosphatephosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (186 aa)
LBAT_11873-oxoacyl-[acyl-carrier protein] reductase. (242 aa)
LBAT_1196PTS system IIA component. (126 aa)
LBAT_1198Cyclase. (342 aa)
LBAT_1201Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. (760 aa)
nadKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa)
LBAT_1205GTP pyrophosphokinase. (210 aa)
LBAT_1226hydroxymethylglutaryl-CoA synthase. (387 aa)
LBAT_1229Truncated acetyl-CoA acetyltransferase. (289 aa)
LBAT_1230UTP-glucose-1-phosphate uridylyltransferase. (299 aa)
LBAT_1235UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (380 aa)
LBAT_1240Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (189 aa)
LBAT_1245Phosphoketolase. (799 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (307 aa)
LBAT_1260Exopolyphosphatase. (314 aa)
LBAT_1263Exopolyphosphatase. (509 aa)
udkUridine kinase. (213 aa)
pyrR-2Pyrimidine regulator; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (176 aa)
LBAT_1271D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
LBAT_1304Lipid kinase. (290 aa)
gatBaspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa)
gatAaspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (480 aa)
gatCaspartyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (100 aa)
nadENAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (276 aa)
LBAT_1318Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (492 aa)
LBAT_1325Aspartate aminotransferase. (392 aa)
LBAT_1328Hypothetical protein. (314 aa)
LBAT_1345NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family. (252 aa)
LBAT_1346UDP-galactose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (330 aa)
LBAT_1353Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (874 aa)
LBAT_1356PTS system mannose-specific IID component. (306 aa)
LBAT_1357PTS system mannose-specific IIC component. (273 aa)
LBAT_1358PTS system mannose-specific IIAB components. (336 aa)
LBAT_1363NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (459 aa)
LBAT_1384Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family. (304 aa)
coaA-2Pantothenate kinase. (304 aa)
LBAT_1395Transketolase; Belongs to the transketolase family. (666 aa)
talFructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
LBAT_1397PTS system IIC component. (330 aa)
LBAT_1415Guanylate kinase. (179 aa)
LBAT_1437PTS system fructose-specific IIABC components. (659 aa)
pfkB1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (304 aa)
LBAT_1444Aspartate racemase; Belongs to the aspartate/glutamate racemases family. (250 aa)
LBAT_1462Oxidoreductase. (182 aa)
LBAT_1463Oxidoreductase. (179 aa)
LBAT_1481PTS system mannose/fructose/sorbose-specific-specific IIC component. (286 aa)
LBAT_1483PTS system mannose/fructose/sorbose-specific-specific IIA component. (148 aa)
LBAT_1495Aminopeptidase. (842 aa)
LBAT_1506Maltose phosphorylase. (757 aa)
LBAT_1507Neopullulanase; Belongs to the glycosyl hydrolase 13 family. (574 aa)
LBAT_1508Oligo-1,6-glucosidase. (552 aa)
LBAT_15134-carboxymuconolactone decarboxylase. (97 aa)
glpK-2Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (500 aa)
LBAT_1525Phosphomethylpyrimidine kinase. (270 aa)
LBAT_1530Cobyric acid synthase. (228 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (264 aa)
LBAT_1537Phosphomethylpyrimidine kinase. (274 aa)
LBAT_1542Prenyltransferase, ubia family. (336 aa)
LBAT_1543Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
guaCGuanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. (330 aa)
asnAAsparagine synthase. (337 aa)
dltCD-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (79 aa)
dltAD-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] (504 aa)
LBAT_1573Truncated enolase. (358 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (241 aa)
LBAT_1640Deoxyadenosine kinase. (215 aa)
LBAT_16496-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (464 aa)
LBAT_1650Pyruvate oxidase; Belongs to the TPP enzyme family. (600 aa)
Your Current Organism:
Lactobacillus acetotolerans
NCBI taxonomy Id: 1600
Other names: ATCC 43578, CCUG 32229, CIP 103180, DSM 20749, JCM 3825, L. acetotolerans, LMG 10751, LMG:10751, Lactobacillus acetitolerans, NBI 3014
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