STRINGSTRING
lysS lysS OJG78224.1 OJG78224.1 OJG78074.1 OJG78074.1 ligA ligA OJG77888.1 OJG77888.1 OJG77898.1 OJG77898.1 OJG77621.1 OJG77621.1 OJG77676.1 OJG77676.1 OJG77337.1 OJG77337.1 OJG81500.1 OJG81500.1 pheT pheT metG metG OJG77008.1 OJG77008.1 OJG81242.1 OJG81242.1 rnr rnr recO recO efp-2 efp-2 pnp pnp rpsL rpsL OJG76594.1 OJG76594.1 OJG76445.1 OJG76445.1 rho rho OJG80652.1 OJG80652.1 OJG80225.1 OJG80225.1 OJG79877.1 OJG79877.1 aspS aspS efp efp OJG82395.1 OJG82395.1 polC polC nusA nusA OJG82541.1 OJG82541.1 OJG82554.1 OJG82554.1 OJG79329.1 OJG79329.1 asnS asnS OJG79344.1 OJG79344.1 rplB rplB rpsQ rpsQ infA infA recG recG ruvA ruvA rsgA rsgA OJG78379.1 OJG78379.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lysSlysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (497 aa)
OJG78224.1CMP-binding protein. (308 aa)
OJG78074.1Cold shock protein 1. (73 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (678 aa)
OJG77888.123S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (454 aa)
OJG77898.1Competence protein ComEA helix-hairpin-helix repeat region. (724 aa)
OJG77621.1Multiple sugar-binding transport ATP-binding protein MsmK; Belongs to the ABC transporter superfamily. (369 aa)
OJG77676.1ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (383 aa)
OJG77337.1DNA polymerase III, alpha subunit. (1095 aa)
OJG81500.1Cold shock protein. (72 aa)
pheTphenylalanine-tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (806 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (669 aa)
OJG77008.1Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (169 aa)
OJG81242.1Cold shock-like protein CspLA. (66 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (779 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (263 aa)
efp-2Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (187 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (707 aa)
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (137 aa)
OJG76594.1General stress protein. (126 aa)
OJG76445.1Single-stranded DNA-binding protein. (103 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (425 aa)
OJG80652.1tRNA-binding protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (203 aa)
OJG80225.1ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (369 aa)
OJG79877.1Major cold shock protein. (66 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
OJG82395.123S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (457 aa)
polCDNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1445 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (415 aa)
OJG82541.1Hypothetical protein; Belongs to the CvfB family. (283 aa)
OJG82554.1Ribosomal protein S1. (407 aa)
OJG79329.1Cold shock-like protein CspLA. (69 aa)
asnSasparaginyl-tRNA synthetase. (432 aa)
OJG79344.1Spermidine/putrescine ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (343 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (262 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (87 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (671 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (177 aa)
rsgARibosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (302 aa)
OJG78379.1S1 RNA-binding protein. (150 aa)
Your Current Organism:
Enterococcus pallens
NCBI taxonomy Id: 160454
Other names: ATCC BAA-351, CCUG 45554, E. pallens, Enterococcus pallens Tyrrell et al. 2002, NBRC 100697, strain PQ2
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