STRINGSTRING
gcdR gcdR gcdH gcdH PP_0159 PP_0159 gabD-I gabD-I gabT gabT davA davA davB davB PP_0384 PP_0384 PP_0949 PP_0949 hpf hpf PP_2040 PP_2040 sad-I sad-I gbd gbd PP_2799 PP_2799 PP_2868 PP_2868 csiR csiR csiD csiD lhgO lhgO sad-II sad-II PP_3390 PP_3390 PP_3391 PP_3391 PP_3392 PP_3392 PP_3393 PP_3393 PP_3394 PP_3394 PP_3395 PP_3395 PP_3401 PP_3401 dpkA dpkA PP_3603 PP_3603 PP_3649 PP_3649 PP_4108 PP_4108 gabD-II gabD-II PP_4482 PP_4482 ydiJ ydiJ PP_4692 PP_4692 PP_4695 PP_4695 PP_4696 PP_4696 ynfM ynfM amaA amaA amaB amaB ydcJ ydcJ rmf rmf PP_5704 PP_5704
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcdRTranscriptional activator of gcdH, LysR family; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription; Belongs to the LysR transcriptional regulatory family. (305 aa)
gcdHglutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (393 aa)
PP_0159Putative CoA-transferase family III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity; Belongs to the CoA-transferase III family. (406 aa)
gabD-ISuccinate-semialdehyde dehydrogenase (NADP+); Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate. Involved in L-lysine degradation. (480 aa)
gabT4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate. (425 aa)
davA5-aminopentanamidase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. (264 aa)
davBLysine 2-monooxygenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. (560 aa)
PP_0384Transcriptional regulator, AsnC family. (153 aa)
PP_0949Putative ATP-binding protein UPF0042; Displays ATPase and GTPase activities. (284 aa)
hpfRibosome hibernation promoting factor; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily. (102 aa)
PP_2040Major facilitator family transporter. (431 aa)
sad-INAD+-dependent succinate semialdehyde dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Biologicalprocesses : Scavenge (Catabolism). (463 aa)
gbdPutative 4-hydroxybutyrate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation. (380 aa)
PP_2799Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
PP_2868Transcriptional regulator, Cro/CI family. (199 aa)
csiRDNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. (231 aa)
csiDCarbon starvation induced protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (325 aa)
lhgOL-2-hydroxyglutarate oxidase; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism. (416 aa)
sad-IINAD+-dependent succinate semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism). (461 aa)
PP_3390Putative Porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (426 aa)
PP_3391Putative Tartrate MFS transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (438 aa)
PP_3392Homologs of previously reported genes of unknown function. (174 aa)
PP_3393CAIB/BAIF family protein; Belongs to the CoA-transferase III family. (396 aa)
PP_3394Putative 3-hydroxy-3-methylglutaryl-CoA lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (309 aa)
PP_3395Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (321 aa)
PP_3401Homologs of previously reported genes of unknown function. (95 aa)
dpkADelta 1-piperideine-2-carboxylate reductase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines; Belongs to the LDH2/MDH2 oxidoreductase family. (332 aa)
PP_3603Transcriptional regulator, GntR family. (254 aa)
PP_3649Transcriptional regulator, GntR family. (250 aa)
PP_4108Putative 4-aminobutyrate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
gabD-IISuccinate-semialdehyde dehydrogenase (NADP+); Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines. (490 aa)
PP_4482Transcriptional regulator, AraC family. (326 aa)
ydiJPutative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. (1006 aa)
PP_4692Putative aspartate/tyrosine/aromatic aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. (390 aa)
PP_4695Sensory box histidine kinase. (991 aa)
PP_4696Nitrogen regulation protein NR(I). (480 aa)
ynfMEfflux transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins. (425 aa)
amaAL-pipecolate oxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines. (432 aa)
amaBL-piperidine-6-carboxylate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family. (496 aa)
ydcJMetalloprotein, putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknown function. (464 aa)
rmfRibosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family. (71 aa)
PP_5704Homologs of previously reported genes of unknown function. (58 aa)
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.