(16 nodes) Bacterial chemotaxis network (Pseudomonas putida KT2440)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	PP_0802	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (299 aa)
	PP_2111	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor. (521 aa)
	PP_2128	Putative CheV-like chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (311 aa)
	pctB	Methyl-accepting chemotaxis protein PctB; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpA is a chemoreceptor that binds to 12 different L-amino acids and mediates chemotaxis toward these amino acids. (643 aa)
	PP_2257	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor. (521 aa)
	PP_3759	Methylesterase, CheB-like. (191 aa)
	cheR3	Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (273 aa)
	PP_4332	Chemotaxis protein CheW. (159 aa)
	cheBA	Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. (370 aa)
	cheA	Chemotaxis histidine kinase CheA. (747 aa)
	cheZ	Protein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (262 aa)
	cheY	Response regulator for chemotactic signal transduction; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein modification and repair. (124 aa)
	cheR	Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor. (275 aa)
	PP_4393	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process. (309 aa)
	PP_4521	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor. (521 aa)
	mcpS	Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpS is a specific chemoreceptor for 6 tricarboxylic acid (TCA) cycle intermediates (succinate, fumarate, malate, oxaloacetate, citrate and isocitrate), butyrate and acetate. Malate, succinate, fumarate and oxaloacetate cause the strongest chemotactic response. (639 aa)

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_0802	PP_2111	PP_0802	PP_2111	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	0.991
PP_0802	PP_2128	PP_0802	PP_2128	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative CheV-like chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.976
PP_0802	PP_2257	PP_0802	PP_2257	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	0.991
PP_0802	PP_3759	PP_0802	PP_3759	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Methylesterase, CheB-like.	0.827
PP_0802	PP_4332	PP_0802	PP_4332	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Chemotaxis protein CheW.	0.837
PP_0802	PP_4393	PP_0802	PP_4393	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	0.971
PP_0802	PP_4521	PP_0802	PP_4521	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	0.991
PP_0802	cheA	PP_0802	PP_4338	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Chemotaxis histidine kinase CheA.	0.998
PP_0802	cheBA	PP_0802	PP_4337	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.	0.939
PP_0802	cheR	PP_0802	PP_4392	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor.	0.867
PP_0802	cheR3	PP_0802	PP_3760	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.674
PP_0802	cheY	PP_0802	PP_4340	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Response regulator for chemotactic signal transduction; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein modification and repair.	0.755
PP_0802	cheZ	PP_0802	PP_4339	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Protein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).	0.955
PP_0802	mcpS	PP_0802	PP_4658	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpS is a specific chemoreceptor for 6 tricarboxylic acid (TCA) cycle intermediates (succinate, fumarate, malate, oxaloacetate, citrate and isocitrate), butyrate and acetate. Malate, succinate, fumarate and oxaloacetate cause the strongest chemotactic response.	0.963
PP_0802	pctB	PP_0802	PP_2249	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	Methyl-accepting chemotaxis protein PctB; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpA is a chemoreceptor that binds to 12 different L-amino acids and mediates chemotaxis toward these amino acids.	0.957
PP_2111	PP_0802	PP_2111	PP_0802	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.	0.991
PP_2111	PP_2128	PP_2111	PP_2128	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	Putative CheV-like chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.981
PP_2111	PP_2257	PP_2111	PP_2257	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	0.919
PP_2111	PP_3759	PP_2111	PP_3759	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	Methylesterase, CheB-like.	0.978
PP_2111	PP_4332	PP_2111	PP_4332	Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.	Chemotaxis protein CheW.	0.989