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aroE-3 aroE-3 hbdH hbdH benD benD PP_3225 PP_3225 paaH paaH ptxD ptxD PP_3384 PP_3384 glcE glcE hbd hbd PP_3768 PP_3768 adhP adhP ybdR ybdR icd icd idh idh zwfB zwfB gntZ gntZ gpsA gpsA glxR glxR aroE aroE lcdH lcdH pdxA pdxA PP_0500 PP_0500 ribD ribD bdhA bdhA PP_0581 PP_0581 PP_0592 PP_0592 mdh mdh PP_0664 PP_0664 hprA hprA hisD hisD zwfA zwfA udh udh ghrB ghrB algD algD panE panE hom hom dxr dxr frmA frmA ldhA ldhA PP_1707 PP_1707 rfbD rfbD PP_1852 PP_1852 murB murB leuB leuB PP_2047 PP_2047 PP_2049 PP_2049 pdxB pdxB fadB fadB PP_2325 PP_2325 aroE-2 aroE-2 calA calA yqhD yqhD PP_2533 PP_2533 PP_2608 PP_2608 zwf zwf serA serA maeB maeB dld2 dld2 ilvC ilvC mmsB mmsB PP_4589 PP_4589 PP_4452 PP_4452 PP_4316 PP_4316 gbd gbd yiaY yiaY dhaT dhaT udg udg PP_2998 PP_2998
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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textmining
co-expression
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aroE-3Shikimate dehydrogenase-related enzyme; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa)
hbdH3-hydroxybutyrate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
benD1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
PP_3225D-isomer specific 2-hydroxyacid dehydrogenase family protein. (314 aa)
paaH3-hydroxyadipyl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (505 aa)
ptxDPutative phosphonate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Centralintermediarymetabolism : Phosphorus compounds; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
PP_3384Gluconate 2-dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme; Energy metabolism. (246 aa)
glcEGlycolate oxidase, putative FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (350 aa)
hbd3-hydroxybutyryl-CoA dehydrogenase. (282 aa)
PP_3768Putative shikimate 5-dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Amino acid biosynthesis. (273 aa)
adhPShort-chain alcohol dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Anaerobic. (336 aa)
ybdRPutative oxidoreductase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. (400 aa)
icdIsocitrate dehydrogenase, NADP(+)-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic. (418 aa)
idhIsocitrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the monomeric-type IDH family. (741 aa)
zwfBGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (501 aa)
gntZPutative 6-phosphogluconate dehydrogenase, decarboxylating; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (327 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa)
glxRTartronate semialdehyde reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. (297 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (274 aa)
lcdHL-carnitine dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (321 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa)
PP_0500dTDP-4-rhamnose reductase-related protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (294 aa)
ribDDiaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (378 aa)
bdhA2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (362 aa)
PP_05813-oxoacyl-(Acyl-carrier-protein) reductase. (457 aa)
PP_0592Oxidoreductase, short chain dehydrogenase/reductase family. (228 aa)
mdhPutative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (310 aa)
PP_0664Homoserine dehydrogenase; Function of strongly homologous gene; enzyme; Amino acid biosynthesis. (347 aa)
hprAGlycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (441 aa)
zwfAGlucose 6-phosphate-1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
udhUronate dehydrogenase; Catalyzes the oxidation of beta-D-galacturonate and beta-D- glucuronate to galactarate and D-glucarate, respectively. Belongs to the NAD(P)-dependent epimerase/dehydratase family. (268 aa)
ghrB2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)
algDGDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). (438 aa)
panEPutative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (305 aa)
homHomoserine dehydrogenase. (434 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (404 aa)
frmAFormaldehyde dehydrogenase, glutathione-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Fermentation. (371 aa)
ldhAD-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa)
PP_1707D-isomer specific 2-hydroxyacid dehydrogenase family protein. (316 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (300 aa)
PP_1852Putative enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis. (249 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (351 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (360 aa)
PP_20473-hydroxyacyl-CoA dehydrogenase family protein. (412 aa)
PP_2049Alcohol dehydrogenase, iron-containing. (387 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (380 aa)
fadBenoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (715 aa)
PP_23252-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa)
aroE-2Putative quinate/shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa)
calAConiferyl alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (350 aa)
yqhDAlcohol dehydrogenase, NAD(P)-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (385 aa)
PP_2533D-isomer specific 2-hydroxyacid dehydrogenase family protein. (331 aa)
PP_2608Shikimate dehydrogenase family protein. (269 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (485 aa)
serAD-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase; Function experimentally demonstrated in the studied species; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
maeBMalic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (422 aa)
dld2D-lactate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (936 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
mmsB3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)
PP_4589D-isomer specific 2-hydroxyacid dehydrogenase family protein. (310 aa)
PP_4452NAD/NADP octopine/nopaline dehydrogenase family protein. (359 aa)
PP_4316D-isomer specific 2-hydroxyacid dehydrogenase family protein. (312 aa)
gbdPutative 4-hydroxybutyrate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation. (380 aa)
yiaYFe-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Central intermediary metabolism. (387 aa)
dhaT1,3-propanediol dehydrogenase. (394 aa)
udgUDP-glucose 6-dehydrogenase. (442 aa)
PP_29982-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa)
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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