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PP_0235 PP_0235 katE katE ompR ompR pdxA pdxA sodB sodB fumC-I fumC-I sodA sodA cysNC cysNC PP_1651 PP_1651 fumC-II fumC-II lexA-I lexA-I chrR chrR rnhA rnhA sbp-I sbp-I cheY cheY cysK cysK recN recN sbp-II sbp-II rep rep tonB tonB phoB phoB
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PP_0235Peroxidase. (212 aa)
katEHydroperoxidase - self catalytic heme d synthase; Serves to protect cells from the toxic effects of hydrogen peroxide. (711 aa)
ompRTwo-component system DNA-binding response transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. (246 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa)
sodBSuperoxide dismutase (Fe); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. (198 aa)
fumC-IFumarate hydratase (class 2); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (459 aa)
sodASuperoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (210 aa)
cysNCSulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (633 aa)
PP_1651Two-component response regulator; Function of strongly homologous gene; regulator; Regulatory functions. (253 aa)
fumC-IIFumarate hydratase (class 2); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
lexA-ITranscriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (202 aa)
chrRChromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] (186 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (148 aa)
sbp-ISulfate ABC transporter; Function of homologous gene experimentally demonstrated in an other organism; carrier; Centralintermediarymetabolism : Sulfur metabolism. (332 aa)
cheYResponse regulator for chemotactic signal transduction; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein modification and repair. (124 aa)
cysKCysteine synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa)
recNFactor used in recombination and DNA repair; May be involved in recombinational repair of damaged DNA. (557 aa)
sbp-IISulfate ABC transporter; Function of homologous gene experimentally demonstrated in an other organism; carrier; Centralintermediarymetabolism : Sulfur metabolism. (342 aa)
repHelicase a single-stranded DNA dependent ATPase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (669 aa)
tonBProtein TonB. (243 aa)
phoBTwo-component system DNA-binding transcriptional dual response regulator PhoB; Function experimentally demonstrated in the studied strain; regulator; Centralintermediarymetabolism : Phosphorus compounds. (242 aa)
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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