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sucC sucC gcdH gcdH PP_0159 PP_0159 gabD-I gabD-I gabT gabT aceE aceE gapA gapA zwfA zwfA PP_1845 PP_1845 PP_2037 PP_2037 PP_2217 PP_2217 prpC prpC paaF paaF fcs fcs vdh vdh pobA pobA PP_4030 PP_4030 sucD sucD sdhB sdhB sdhA sdhA gltA gltA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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sucCsuccinyl-CoA synthetase, beta subunit glutaryl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
gcdHglutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (393 aa)
PP_0159Putative CoA-transferase family III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity; Belongs to the CoA-transferase III family. (406 aa)
gabD-ISuccinate-semialdehyde dehydrogenase (NADP+); Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate. Involved in L-lysine degradation. (480 aa)
gabT4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate. (425 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Entner-Doudoroff; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
zwfAGlucose 6-phosphate-1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
PP_1845Enoyl-CoA hydratase/isomerase family protein. (229 aa)
PP_2037Putative Aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (260 aa)
PP_2217enoyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
prpCMethylcitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the citrate synthase family. (375 aa)
paaFenoyl-CoA hydratase-isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism); Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
fcsferuloyl-CoA-synthetase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (627 aa)
vdhVanillin dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism); Belongs to the aldehyde dehydrogenase family. (482 aa)
pobAP-hydroxybenzoate hydroxylase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (395 aa)
PP_4030Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (280 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (234 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
gltACitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the citrate synthase family. (429 aa)
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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