7 items (Pseudomonas putida KT2440) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	hexR	DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region. (287 aa)
	PP_0652	Gluconate transporter. (461 aa)
	glk	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family. (319 aa)
	pykA	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family. (484 aa)
	PP_1661	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (752 aa)
	ptxS	2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control. (339 aa)
	pyk	Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_1661	glk	PP_1661	PP_1011	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	0.897
PP_1661	pyk	PP_1661	PP_4301	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.827
PP_1661	pykA	PP_1661	PP_1362	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.	0.884
glk	PP_1661	PP_1011	PP_1661	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.897
glk	hexR	PP_1011	PP_1021	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.	0.986
glk	ptxS	PP_1011	PP_3380	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.	0.755
glk	pykA	PP_1011	PP_1362	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.	0.606
hexR	glk	PP_1021	PP_1011	DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	0.986
hexR	ptxS	PP_1021	PP_3380	DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.	2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.	0.885
ptxS	glk	PP_3380	PP_1011	2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	0.755
ptxS	hexR	PP_3380	PP_1021	2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.	DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.	0.885
pyk	PP_1661	PP_4301	PP_1661	Pyruvate kinase; Belongs to the pyruvate kinase family.	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.827
pyk	pykA	PP_4301	PP_1362	Pyruvate kinase; Belongs to the pyruvate kinase family.	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.	0.913
pykA	PP_1661	PP_1362	PP_1661	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.	Putative Dehydrogenase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.884
pykA	glk	PP_1362	PP_1011	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.	Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.	0.606
pykA	pyk	PP_1362	PP_4301	Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.913