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scpC scpC gabD-I gabD-I gabT gabT bdhA bdhA PP_0582 PP_0582 PP_1157 PP_1157 PP_1394 PP_1394 PP_1845 PP_1845 fadA fadA fadB fadB PP_2215 PP_2215 acd acd PP_2217 PP_2217 sad-I sad-I PP_2799 PP_2799 aacs aacs hbdH hbdH atoA atoA atoB atoB sad-II sad-II paaH paaH paaF paaF PP_3355 PP_3355 PP_3394 PP_3394 mvaB mvaB bktB bktB hbd hbd nicE nicE PP_4030 PP_4030 sdhB sdhB sdhA sdhA sdhD sdhD sdhC sdhC gabD-II gabD-II fabV fabV yqeF yqeF ilvH ilvH ilvI ilvI phaA phaA phaC-II phaC-II
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
scpCpropionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (497 aa)
gabD-ISuccinate-semialdehyde dehydrogenase (NADP+); Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate. Involved in L-lysine degradation. (480 aa)
gabT4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate. (425 aa)
bdhA2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (362 aa)
PP_0582Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
PP_1157Acetolactate synthase; Belongs to the TPP enzyme family. (547 aa)
PP_1394Putative Acetolactate synthase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the TPP enzyme family. (545 aa)
PP_1845Enoyl-CoA hydratase/isomerase family protein. (229 aa)
fadA3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
fadBenoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (715 aa)
PP_2215acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
acdShort-chain acyl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Biologicalprocesses : Scavenge (Catabolism). (375 aa)
PP_2217enoyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
sad-INAD+-dependent succinate semialdehyde dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Biologicalprocesses : Scavenge (Catabolism). (463 aa)
PP_2799Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
aacsAcetoacetyl-coenzyme A synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (650 aa)
hbdH3-hydroxybutyrate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
atoAAcetoacetyl CoA-transferase (subunit A); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (232 aa)
atoBAcetoacetyl CoA-transferase (subunit B); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (218 aa)
sad-IINAD+-dependent succinate semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism). (461 aa)
paaH3-hydroxyadipyl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (505 aa)
paaFenoyl-CoA hydratase-isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism); Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
PP_3355Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
PP_3394Putative 3-hydroxy-3-methylglutaryl-CoA lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (309 aa)
mvaBHydroxymethylglutaryl-CoA lyase. (299 aa)
bktBBeta-ketothiolase BktB; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
hbd3-hydroxybutyryl-CoA dehydrogenase. (282 aa)
nicEMaleate isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate in the aerobic nicotinate degradation pathway. (250 aa)
PP_4030Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (280 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (234 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
sdhDSuccinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa)
sdhCSuccinate dehydrogenase membrane b-556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (128 aa)
gabD-IISuccinate-semialdehyde dehydrogenase (NADP+); Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines. (490 aa)
fabVtrans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (403 aa)
yqeFacetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
ilvHAcetohydroxybutanoate synthase / acetolactate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Pyruvate family. (163 aa)
ilvIAcetohydroxybutanoate synthase / acetolactate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Pyruvate family. (574 aa)
phaAPoly(3-hydroxyalkanoate) polymerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (559 aa)
phaC-IIPoly(3-hydroxyalkanoate) polymerase 2; Function of strongly homologous gene; enzyme. (560 aa)
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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