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| | thrB | Homoserine kinase; Function experimentally demonstrated in the studied genus; enzyme; Belongs to the pseudomonas-type ThrB family. (316 aa) |
| | scpC | propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (497 aa) |
| | gcdH | glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (393 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa) |
| | hemD | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (255 aa) |
| | PP_0188 | Putative Uroporphyrin-III C-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (375 aa) |
| | gabD-I | Succinate-semialdehyde dehydrogenase (NADP+); Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate. Involved in L-lysine degradation. (480 aa) |
| | gabT | 4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate. (425 aa) |
| | PP_0228 | Putative serine acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (310 aa) |
| | cysQ | Adenosine-3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (266 aa) |
| | ltaE | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (346 aa) |
| | glyA-I | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | fdhA | Formaldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (399 aa) |
| | aceF | AceF-S-acetyldihydrolipoate; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (546 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa) |
| | aruC | Acetylornithine aminotransferase 2; Function experimentally demonstrated in the studied strain; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | davA | 5-aminopentanamidase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. (264 aa) |
| | davB | Lysine 2-monooxygenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. (560 aa) |
| | glpE | Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (110 aa) |
| | rpe | Ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Pentose phosphate pathway; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa) |
| | fdoG | Formate dehydrogenase-O major subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (1022 aa) |
| | fdoH | Formate dehydrogenase-O, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (316 aa) |
| | fdoI | Formate dehydrogenase-O, gamma subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (218 aa) |
| | aldB-I | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | ubiX | Putative phenylacrylic acid decarboxylase, padA1; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa) |
| | acoC | Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system. (368 aa) |
| | accC | acetyl-CoA carboxylase - biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa) |
| | accB | acetyl-CoA carboxylase - biotin carboxyl carrier subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa) |
| | PP_0582 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa) |
| | mdh | Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (310 aa) |
| | PP_0662 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (462 aa) |
| | PP_0664 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme; Amino acid biosynthesis. (347 aa) |
| | PP_0665 | Putative glyceraldehyde-3-phosphate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Entner-Doudoroff. (472 aa) |
| | glyA-II | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | gdhA | Glutamate dehydrogenase, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa) |
| | mqo-I | Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme; Energymetabolism : TCA cycle. (502 aa) |
| | hprA | Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. (695 aa) |
| | fruA | Fructose PTS permease - IIBC component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism. (580 aa) |
| | cysE | Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family. (261 aa) |
| | PP_0860 | Putative Sulfite reductase, flavoprotein component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (849 aa) |
| | PP_0897 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | fumC-I | Fumarate hydratase (class 2); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (459 aa) |
| | arcC | Carbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the carbamate kinase family. (309 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Entner-Doudoroff; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa) |
| | glk | Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family. (319 aa) |
| | zwfA | Glucose 6-phosphate-1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa) |
| | eda | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. (235 aa) |
| | PP_1110 | Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family. (234 aa) |
| | pdxH | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa) |
| | PP_1165 | Homologs of previously reported genes of unknown function. (289 aa) |
| | PP_1218 | Putative acyl-CoA thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (150 aa) |
| | dapA-I | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa) |
| | mqo-II | Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme; Energymetabolism : TCA cycle. (527 aa) |
| | ghrB | 2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa) |
| | cysD | Sulfate adenylyltransferase subunit 2. (305 aa) |
| | cysNC | Sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (633 aa) |
| | pykA | Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family. (484 aa) |
| | pcaF-I | beta-ketoadipyl-CoA thiolase; Function experimentally demonstrated in the studied strain; enzyme; Energy metabolism; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) |
| | pcaB | 3-carboxy-cis,cis-muconate cycloisomerase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (450 aa) |
| | pcaD | 3-oxoadipate enol-lactonase 2; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (263 aa) |
| | pcaC | 4-carboxymuconolactone decarboxylase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (130 aa) |
| | hom | Homoserine dehydrogenase. (434 aa) |
| | thrC | Threonine synthase. (469 aa) |
| | patD | Medium chain aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family. (474 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (875 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (383 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (344 aa) |
| | dapC | N-succinyl-L,L-diaminopimelate aminotransferase alternative; Function of strongly homologous gene; enzyme; Aminoacidbiosynthesis : Aspartate family. (398 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa) |
| | frmA | Formaldehyde dehydrogenase, glutathione-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Fermentation. (371 aa) |
| | frmC | S-formylglutathione hydrolase / S-lactoylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa) |
| | ldhA | D-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa) |
| | PP_1703 | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (1341 aa) |
| | nirB | Nitrite reductase [NAD(P)H] large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (850 aa) |
| | nirD | Nitrite reductase. (120 aa) |
| | PP_1709 | Fumarylacetoacetate hydrolase family protein. (236 aa) |
| | fumC-II | Fumarate hydratase (class 2); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | cpsG | Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. (453 aa) |
| | PP_1791 | Putative Aldolase/synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (534 aa) |
| | pgi-I | Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (554 aa) |
| | PP_1845 | Enoyl-CoA hydratase/isomerase family protein. (229 aa) |
| | folD-I | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) |
| | gltX | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (493 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (297 aa) |
| | PP_2036 | Putative 4-hydroxy-tetrahydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Aminoacidbiosynthesis : Aspartate family; Belongs to the DapA family. (295 aa) |
| | PP_2037 | Putative Aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (260 aa) |
| | fadA | 3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | lysA-I | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (410 aa) |
| | gdhB | NAD-specific glutamate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines. (1621 aa) |
| | ppsA | Phosphoenolpyruvate synthetase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | cobA | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (246 aa) |
| | acnA-I | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa) |
| | fadB | enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (715 aa) |
| | pcaF-II | Beta-ketoadipyl CoA thiolase, beta component; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (391 aa) |
| | gapB | Glyceraldehyde-3-phosphate dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Entner-Doudoroff; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (487 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (308 aa) |
| | puuA-I | Glutamate-putrescine ligase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the glutamine synthetase family. (448 aa) |
| | PP_2183 | Putative Formate dehydrogenase, gamma subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (160 aa) |
| | PP_2184 | Putative Formate dehydrogenase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (525 aa) |
| | PP_2185 | Putative Formate dehydrogenase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (960 aa) |
| | PP_2186 | Putative Formate dehydrogenase, delta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (67 aa) |
| | phnX | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (275 aa) |
| | phnW | 2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (368 aa) |
| | PP_2213 | Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (561 aa) |
| | PP_2215 | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | acd | Short-chain acyl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Biologicalprocesses : Scavenge (Catabolism). (375 aa) |
| | PP_2217 | enoyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | folD-II | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (244 aa) |
| | acnB | Bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the aconitase/IPM isomerase family. (869 aa) |
| | cysI | Sulphite reductase hemoprotein, beta subunit. (550 aa) |
| | calA | Coniferyl alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (350 aa) |
| | nfnB | 6,7-dihydropteridine reductase; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (217 aa) |
| | PP_2486 | NADH-dependent flavin oxidoreductase, Oye family. (374 aa) |
| | sad-I | NAD+-dependent succinate semialdehyde dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Biologicalprocesses : Scavenge (Catabolism). (463 aa) |
| | PP_2504 | Putative tautomerase K2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 4-oxalocrotonate tautomerase family. (69 aa) |
| | gllD | 4-oxalomesaconate tautomerase; Catalyzes the tautomerization of the 4-oxalomesaconic acid keto (OMAketo) generated by GalA dioxygenase to 4-oxalomesaconic acid enol (OMAenol). Mediates the second step in gallate degradation pathway. (361 aa) |
| | gllC | 4-carboxy-4-hydroxy-2-oxoadipic acid aldolase; Catalyzes the conversion of 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA) to pyruvate and oxaloacetate, the last step of gallate degradation pathway; Belongs to the LigK/PcmE family. (238 aa) |
| | glllA | Gallate dioxygenase; Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Mediates the first step of gallate degradation pathway. (420 aa) |
| | PP_2533 | D-isomer specific 2-hydroxyacid dehydrogenase family protein. (331 aa) |
| | dapA-II | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (288 aa) |
| | qedH-I | Quinoprotein ethanol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (631 aa) |
| | PP_2677 | Homologs of previously reported genes of unknown function. (255 aa) |
| | qedH-II | Quinoprotein ethanol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (595 aa) |
| | aldB-II | Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | PP_2744 | Ribose-phosphate pyrophosphokinase family protein. (319 aa) |
| | PP_2799 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa) |
| | PP_2800 | Putative Diaminobutyrate-2-oxoglutarate transaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa) |
| | prr | Gamma-aminobutyraldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family. (474 aa) |
| | dhaT | 1,3-propanediol dehydrogenase. (394 aa) |
| | ethA | FAD-containing monooxygenase EthA; Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor. Preferentially converts short-chain aliphatic ketones like 2-decanone, 3-decanone and 4-decanone. Some acyclic ketones are converted not only to the alkylacetates, but also methyl- and ethylesters are obtained, indicating insertion of oxygen on both sides of the keto group; Belongs to the FAD-binding monooxygenase family. (508 aa) |
| | fucD | L-fuconate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Pentose phosphate pathway; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (411 aa) |
| | ureA | Urease subunit gamma; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the urease gamma subunit family. (100 aa) |
| | ureB | Urease subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the urease beta subunit family. (105 aa) |
| | ureC | Urease subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (567 aa) |
| | csiD | Carbon starvation induced protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (325 aa) |
| | lhgO | L-2-hydroxyglutarate oxidase; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism. (416 aa) |
| | hemB | 5-aminolevulinate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Heme, porphyrin, and cobalamin; Belongs to the ALAD family. (324 aa) |
| | mqo-III | Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme; Energymetabolism : TCA cycle. (539 aa) |
| | PP_2932 | Amidase family protein. (567 aa) |
| | PP_3136 | Putative O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (174 aa) |
| | PP_3148 | Putative Glutamine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamine synthetase family. (452 aa) |
| | sad-II | NAD+-dependent succinate semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism). (461 aa) |
| | benA | Benzoate 1,2-dioxygenase subunit alpha; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (452 aa) |
| | benB | Benzoate 1,2-dioxygenase subunit beta; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (161 aa) |
| | benC | Benzoate 1,2-dioxygenase electron transfer component; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (336 aa) |
| | benD | 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa) |
| | catA-II | Catechol 1,2-dioxygenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (304 aa) |
| | nemA | N-ethylmaleimide reductase, FMN-linked; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (365 aa) |
| | garK | Glycerate kinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the glycerate kinase type-1 family. (379 aa) |
| | PP_3205 | Fumarylacetoacetate hydrolase family protein. (330 aa) |
| | paaZ | oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (684 aa) |
| | paaE | Ring 1,2-phenylacetyl-CoA epoxidase, reductase subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (358 aa) |
| | paaD | Putative subunit of phenylacetate degradation enzyme; Function experimentally demonstrated in the studied species; putative regulator; Energy metabolism. (177 aa) |
| | paaC | Ring 1,2-phenylacetyl-CoA epoxidase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (252 aa) |
| | paaB | Ring 1,2-phenylacetyl-CoA epoxidase regulatory subunit; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme; Energy metabolism. (93 aa) |
| | paaA | Ring 1,2-phenylacetyl-CoA epoxidase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (329 aa) |
| | paaK | phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (439 aa) |
| | paaJ | 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa) |
| | paaH | 3-hydroxyadipyl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (505 aa) |
| | paaG | 1,2-epoxyphenylacetyl-CoA isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (263 aa) |
| | paaF | enoyl-CoA hydratase-isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism); Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | paoA | Promiscuous aromatic aldehyde dehydrogenase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (175 aa) |
| | paoB | Promiscuous aromatic aldehyde dehydrogenase, FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknownfunction : Enzymes of unknown specificity. (333 aa) |
| | paoC | Promiscuous aromatic aldehyde dehydrogenase, molybdopterin-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (738 aa) |
| | hemBB | Porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (333 aa) |
| | PP_3355 | Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa) |
| | vdh | Vanillin dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism); Belongs to the aldehyde dehydrogenase family. (482 aa) |
| | ptxD | Putative phosphonate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Centralintermediarymetabolism : Phosphorus compounds; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa) |
| | kguK | Putative 2-ketogluconokinase; Function experimentally demonstrated in the studied genus; putative enzyme; Energy metabolism. (316 aa) |
| | PP_3383 | Gluconate 2-dehydrogenase flavoprotein subunit; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism. (594 aa) |
| | PP_3384 | Gluconate 2-dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme; Energy metabolism. (246 aa) |
| | gnuK | D-gluconate kinase; Function experimentally demonstrated in the studied strain; enzyme. (179 aa) |
| | PP_3443 | Putative glyceraldehyde-3-phosphate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Entner-Doudoroff. (539 aa) |
| | peaE | Phenylacetaldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family. (497 aa) |
| | allE | Putative S-ureidoglycine aminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation. (278 aa) |
| | pobA | P-hydroxybenzoate hydroxylase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (395 aa) |
| | pgm | Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. (545 aa) |
| | PP_3648 | Carboxymuconolactone decarboxylase family protein. (129 aa) |
| | catA-I | Catechol 1,2-dioxygenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (311 aa) |
| | catC | Muconolactone Delta-isomerase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the muconolactone Delta-isomerase family. (96 aa) |
| | catB | Muconate cycloisomerase 1; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (373 aa) |
| | PP_3726 | Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa) |
| | vanA | Vanillate O-demethylase oxygenase subunit; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (355 aa) |
| | vanB | Vanillate O-demethylase oxidoreductase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (316 aa) |
| | glcD | Glycolate oxidase, putative FAD-linked subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (499 aa) |
| | glcE | Glycolate oxidase, putative FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (350 aa) |
| | glcF | Glycolate oxidase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (411 aa) |
| | bktB | Beta-ketothiolase BktB; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | hbd | 3-hydroxybutyryl-CoA dehydrogenase. (282 aa) |
| | dapF-2 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (268 aa) |
| | adhP | Short-chain alcohol dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Anaerobic. (336 aa) |
| | nicF | Maleamate amidohydrolase; Maleamate amidase that transforms maleamate into maleate and ammonia in the aerobic nicotinate degradation pathway. (213 aa) |
| | nicE | Maleate isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate in the aerobic nicotinate degradation pathway. (250 aa) |
| | nicD | N-formylmaleamate deformylase; Deformylase that catalyzes the conversion of N-formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway. (268 aa) |
| | nicC | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. (382 aa) |
| | nicX | 2,5-dihydroxypyridine 5,6-dioxygenase; Catalyzes the dioxygenolytic ring cleavage of 2,5- dihydroxypyridine between carbons 5 and 6 generating N-formylmaleamate in the aerobic nicotinate degradation pathway. (350 aa) |
| | nicA | Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). (157 aa) |
| | nicB | Nicotinate dehydrogenase subunit B; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). (1187 aa) |
| | pcaI | 3-oxoadipate CoA-transferase subunit A; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (231 aa) |
| | pcaJ | 3-oxoadipate CoA-transferase subunit A; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (213 aa) |
| | cysG | Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (463 aa) |
| | icd | Isocitrate dehydrogenase, NADP(+)-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic. (418 aa) |
| | idh | Isocitrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the monomeric-type IDH family. (741 aa) |
| | PP_4030 | Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (280 aa) |
| | zwfB | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (501 aa) |
| | gntZ | Putative 6-phosphogluconate dehydrogenase, decarboxylating; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (327 aa) |
| | aceA | Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : TCA cycle. (441 aa) |
| | sucD | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit glutaryl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | lpdG | Dihydrolipoyl dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Folic acid. (478 aa) |
| | sucB | 2-oxoglutarate dehydrogenase dihydrolipoyltranssuccinylase subunit; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (407 aa) |
| | sucA | 2-oxoglutarate decarboxylase, thiamine-requiring E1 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : TCA cycle. (943 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (234 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa) |
| | sdhD | Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa) |
| | sdhC | Succinate dehydrogenase membrane b-556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. (128 aa) |
| | gltA | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the citrate synthase family. (429 aa) |
| | pvdH | Diaminobutyrate-2-oxoglutarate transaminase; Function experimentally demonstrated in the studied genus; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa) |
| | xdhA | Xanthine dehydrogenase subunit XdhA; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (484 aa) |
| | xdhB | Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (799 aa) |
| | pucM | 5-hydroxyisourate hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (117 aa) |
| | ttuD | Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (424 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa) |
| | PP_4310 | Putative Hydantoin racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (242 aa) |
| | PP_4399 | Putative Glutamine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamine synthetase family. (413 aa) |
| | lpdV | Dihydrolipoyl dehydrogenase component of branched-chain alpha-keto acid dehydrogenase complex; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (459 aa) |
| | PP_4421 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa) |
| | gabD-II | Succinate-semialdehyde dehydrogenase (NADP+); Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines. (490 aa) |
| | PP_4423 | Homologs of previously reported genes of unknown function. (331 aa) |
| | PP_4432 | Putative Xaa-Pro aminopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides. (396 aa) |
| | lysC | Aspartokinase; Involved in the biosynthesis of L-aspartate-beta-semialdehyde which is a central intermediate in the biosynthesis of different amino acids (L-lysine, L-methionine, L-threonine). Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4- phospho-L-aspartate. (411 aa) |
| | acsA-I | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (696 aa) |
| | PP_4547 | Putative Glutamine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamine synthetase family. (454 aa) |
| | cysK | Cysteine synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa) |
| | hmgC | Maleylacetoacetate isomerase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (210 aa) |
| | hmgB | Fumarylacetoacetase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. (430 aa) |
| | hmgA | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. (433 aa) |
| | fabV | trans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (403 aa) |
| | yqeF | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | PP_4638 | Methylenetetrahydrofolate reductase. (495 aa) |
| | pcaG | Protocatechuate 3,4-dioxygenase alpha chain; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). (201 aa) |
| | pcaH | Protocatechuate 3,4-dioxygenase beta chain; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (239 aa) |
| | pgi-II | Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme. (554 aa) |
| | acsA-II | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa) |
| | tpiA | Triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (267 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase. (427 aa) |
| | rhdA | Thiosulfate sulfurtransferase. (269 aa) |
| | serB | Phosphoserine phosphatase; Function experimentally demonstrated in the studied genus; enzyme; Aminoacidbiosynthesis : Serine family. (415 aa) |
| | fba | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | tktA | Transketolase A; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Folic acid; Belongs to the methylenetetrahydrofolate reductase family. (295 aa) |
| | fbp | Fructose-1,6-bisphosphatase, class 1; Function of strongly homologous gene; enzyme; Energymetabolism : Glycolysis/gluconeogenesis. (336 aa) |
| | glnA | Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. (468 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa) |
| | gltD | Glutamate synthase (NADPH) beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. (472 aa) |
| | gltB | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. (1481 aa) |
| | maeB | Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (422 aa) |
| | sseA | Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (284 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase; Function experimentally demonstrated in the studied species; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa) |
| | spuB | Glutamylpolyamine synthetase; Function experimentally demonstrated in the studied genus; enzyme; Centralintermediarymetabolism : Polyamine biosynthesis; Belongs to the glutamine synthetase family. (452 aa) |
| | spuI | Glutamylpolyamine synthetase; Function experimentally demonstrated in the studied genus; enzyme; Centralintermediarymetabolism : Polyamine biosynthesis; Belongs to the glutamine synthetase family. (458 aa) |
| | lysA-II | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (415 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (287 aa) |
| | amaB | L-piperidine-6-carboxylate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family. (496 aa) |
| | algC | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). (463 aa) |
| | puuA-II | Glutamate-putrescine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the glutamine synthetase family. (460 aa) |
| | PP_5332 | Homologs of previously reported genes of unknown function; Belongs to the glucose-6-phosphate 1-epimerase family. (298 aa) |
| | pycB | Pyruvate carboxylase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (602 aa) |
| | pycA | Pyruvate carboxylase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (471 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (485 aa) |
| | lpd | Dihydrolipoyl dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Folic acid. (466 aa) |
| | peaA | Quinohaemoprotein amine dehydrogenase, alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines. (542 aa) |
