STRINGSTRING
AMM53147.1 AMM53147.1 AMM53151.1 AMM53151.1 pgiA pgiA AMM53208.1 AMM53208.1 AMM53265.1 AMM53265.1 AMM53273.1 AMM53273.1 eno eno pckG pckG AMM53367.1 AMM53367.1 glkA glkA AMM53431.1 AMM53431.1 AMM53521.1 AMM53521.1 fbp fbp AMM54958.1 AMM54958.1 AMM53610.1 AMM53610.1 AMM53611.1 AMM53611.1 AMM53752.1 AMM53752.1 AMM53753.1 AMM53753.1 AMM53754.1 AMM53754.1 AMM53755.1 AMM53755.1 AMM53756.1 AMM53756.1 AMM53757.1 AMM53757.1 pgk pgk AMM53844.1 AMM53844.1 AMM53873.1 AMM53873.1 AMM53876.1 AMM53876.1 AMM53877.1 AMM53877.1 AMM53878.1 AMM53878.1 AMM53879.1 AMM53879.1 AMM53880.1 AMM53880.1 AMM53881.1 AMM53881.1 AMM53882.1 AMM53882.1 AMM53883.1 AMM53883.1 vorD vorD porA porA AMM53886.1 AMM53886.1 porD porD porA-2 porA-2 AMM53889.1 AMM53889.1 AMM53890.1 AMM53890.1 AMM53891.1 AMM53891.1 AMM54977.1 AMM54977.1 AMM53915.1 AMM53915.1 AMM53948.1 AMM53948.1 AMM53949.1 AMM53949.1 AMM54069.1 AMM54069.1 AMM54119.1 AMM54119.1 AMM54120.1 AMM54120.1 AMM54121.1 AMM54121.1 AMM54133.1 AMM54133.1 AMM54138.1 AMM54138.1 AMM54168.1 AMM54168.1 AMM54177.1 AMM54177.1 tpiA tpiA gap gap AMM54390.1 AMM54390.1 AMM54439.1 AMM54439.1 AMM54495.1 AMM54495.1 AMM54496.1 AMM54496.1 AMM54511.1 AMM54511.1 AMM54512.1 AMM54512.1 AMM54513.1 AMM54513.1 AMM54516.1 AMM54516.1 AMM54517.1 AMM54517.1 AMM54518.1 AMM54518.1 pfkC pfkC AMM54543.1 AMM54543.1 AMM54657.1 AMM54657.1 AMM54705.1 AMM54705.1 AMM54738.1 AMM54738.1 AMM54739.1 AMM54739.1 AMM55034.1 AMM55034.1 AMM54814.1 AMM54814.1 AMM54821.1 AMM54821.1 AMM54849.1 AMM54849.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMM53147.1Indolepyruvate oxidoreductase subunit B; Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AMM53151.1Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
pgiAGlucose-6-phosphate isomerase; Catalyzes the formation of D-fructose 6-phosphate from D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal-type GPI family. (189 aa)
AMM53208.1Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
AMM53265.1CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
AMM53273.1Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (624 aa)
AMM53367.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
glkAADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. (455 aa)
AMM53431.1Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
AMM53521.12-keto acid:ferredoxin oxidoreductase subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (615 aa)
fbpFructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
AMM54958.1Indolepyruvate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
AMM53610.1Indolepyruvate oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (646 aa)
AMM53611.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
AMM53752.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
AMM53753.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
AMM53754.1acetyl-CoA carboxylase; Composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
AMM53755.1glutaconyl-CoA decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AMM53756.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
AMM53757.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (409 aa)
AMM53844.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (476 aa)
AMM53873.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
AMM53876.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AMM53877.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AMM53878.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
AMM53879.1Protein frxA; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AMM53880.1AcaC; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AMM53881.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AMM53882.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa)
AMM53883.1Pyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
vorD2-ketoisovalerate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
porAPyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
AMM53886.12-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
porDPyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
porA-2Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AMM53889.1Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
AMM53890.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AMM53891.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (837 aa)
AMM54977.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
AMM53915.1Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AMM53948.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AMM53949.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa)
AMM54069.1Pyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
AMM54119.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AMM54120.1GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
AMM54121.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
AMM54133.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AMM54138.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (818 aa)
AMM54168.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AMM54177.1Biotin--protein ligase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (229 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AMM54390.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
AMM54439.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AMM54495.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield l-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AMM54496.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AMM54511.12-keto acid:ferredoxin oxidoreductase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AMM54512.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
AMM54513.12-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AMM54516.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AMM54517.12-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AMM54518.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
pfkC6-phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (452 aa)
AMM54543.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AMM54657.1Acetyl CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
AMM54705.1XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
AMM54738.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
AMM54739.1Formate dehydrogenase; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (166 aa)
AMM55034.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
AMM54814.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
AMM54821.1Alanine aminotransferase; Catalyzes the transamination of pyruvate or with glutamate; activity is seen with alanine, glutamate, and aspartate with either 2-oxoglutarate or pyruvate as the amino acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AMM54849.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (665 aa)
Your Current Organism:
Pyrococcus kukulkanii
NCBI taxonomy Id: 1609559
Other names: DSM 101590, P. kukulkanii, Pyrococcus kukulkanii Callac et al. 2016, Pyrococcus sp. NCB100, Souchotheque de Bretagne BG1337, strain NCB100
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