STRINGSTRING
AMM55041.1 AMM55041.1 moaA moaA priL priL purF purF AMM53431.1 AMM53431.1 AMM53521.1 AMM53521.1 AMM54956.1 AMM54956.1 AMM53610.1 AMM53610.1 AMM53704.1 AMM53704.1 AMM53730.1 AMM53730.1 AMM53745.1 AMM53745.1 AMM54903.1 AMM54903.1 AMM53800.1 AMM53800.1 queE queE vorD vorD porD porD AMM53889.1 AMM53889.1 AMM53945.1 AMM53945.1 AMM53949.1 AMM53949.1 AMM53955.1 AMM53955.1 AMM54059.1 AMM54059.1 AMM54131.1 AMM54131.1 AMM54231.1 AMM54231.1 nadA nadA AMM54303.1 AMM54303.1 AMM54314.1 AMM54314.1 AMM54317.1 AMM54317.1 AMM54322.1 AMM54322.1 taw1 taw1 AMM54496.1 AMM54496.1 thiC thiC nth nth AMM55027.1 AMM55027.1 AMM54708.1 AMM54708.1 AMM55030.1 AMM55030.1 AMM54771.1 AMM54771.1 AMM54776.1 AMM54776.1 AMM54779.1 AMM54779.1 AMM54789.1 AMM54789.1 AMM55033.1 AMM55033.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMM55041.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
moaAMolybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (306 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (389 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (442 aa)
AMM53431.1Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
AMM53521.12-keto acid:ferredoxin oxidoreductase subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (615 aa)
AMM54956.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
AMM53610.1Indolepyruvate oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (646 aa)
AMM53704.1Aldehyde:ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)
AMM53730.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AMM53745.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AMM54903.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (411 aa)
AMM53800.1S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (344 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (253 aa)
vorD2-ketoisovalerate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
porDPyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
AMM53889.1Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
AMM53945.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
AMM53949.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa)
AMM53955.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AMM54059.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (408 aa)
AMM54131.1Molybdopterin-guanine dinucleotide biosynthesis protein MobB; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
AMM54231.1Aldehyde:ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (302 aa)
AMM54303.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
AMM54314.1Threonylcarbamoyladenosine tRNA methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AMM54317.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
AMM54322.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
taw1tRNA-modifying protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (338 aa)
AMM54496.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (425 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (215 aa)
AMM55027.1DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
AMM54708.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
AMM55030.1Pyruvate-formate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
AMM54771.1NADH-plastoquinone oxidoreductase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AMM54776.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
AMM54779.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the complex I 20 kDa subunit family. (192 aa)
AMM54789.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
AMM55033.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
Your Current Organism:
Pyrococcus kukulkanii
NCBI taxonomy Id: 1609559
Other names: DSM 101590, P. kukulkanii, Pyrococcus kukulkanii Callac et al. 2016, Pyrococcus sp. NCB100, Souchotheque de Bretagne BG1337, strain NCB100
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.