(10 nodes) Thiamin diphosphate-binding fold network (Pyrococcus kukulkanii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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protein homology

Your Input:
	AMM54516.1	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
	AMM53521.1	2-keto acid:ferredoxin oxidoreductase subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (615 aa)
	AMM53610.1	Indolepyruvate oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (646 aa)
	porA	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
	AMM53886.1	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	porA-2	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
	AMM53889.1	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
	AMM54512.1	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
	AMM54513.1	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	AMM54517.1	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)

Your Current Organism:

Pyrococcus kukulkanii

NCBI taxonomy Id: 1609559
Other names: DSM 101590, P. kukulkanii, Pyrococcus kukulkanii Callac et al. 2016, Pyrococcus sp. NCB100, Souchotheque de Bretagne BG1337, strain NCB100

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMM53886.1	AMM53889.1	TQ32_04860	TQ32_04875	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.744
AMM53886.1	AMM54512.1	TQ32_04860	TQ32_08500	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AMM53886.1	AMM54516.1	TQ32_04860	TQ32_08525	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AMM53886.1	porA	TQ32_04860	TQ32_04855	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMM53886.1	porA-2	TQ32_04860	TQ32_04870	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AMM53889.1	AMM53886.1	TQ32_04875	TQ32_04860	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.744
AMM53889.1	AMM54512.1	TQ32_04875	TQ32_08500	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
AMM53889.1	AMM54513.1	TQ32_04875	TQ32_08505	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMM53889.1	AMM54516.1	TQ32_04875	TQ32_08525	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
AMM53889.1	AMM54517.1	TQ32_04875	TQ32_08530	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMM53889.1	porA	TQ32_04875	TQ32_04855	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMM53889.1	porA-2	TQ32_04875	TQ32_04870	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMM54512.1	AMM53886.1	TQ32_08500	TQ32_04860	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.769
AMM54512.1	AMM53889.1	TQ32_08500	TQ32_04875	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
AMM54512.1	AMM54513.1	TQ32_08500	TQ32_08505	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMM54512.1	AMM54516.1	TQ32_08500	TQ32_08525	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
AMM54512.1	AMM54517.1	TQ32_08500	TQ32_08530	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AMM54512.1	porA-2	TQ32_08500	TQ32_04870	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.908
AMM54513.1	AMM53889.1	TQ32_08505	TQ32_04875	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMM54513.1	AMM54512.1	TQ32_08505	TQ32_08500	2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999

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