Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Pyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Pyruvate carboxylase subunit A; Catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Trans-homoaconitate synthase; In Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

Citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.

Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology.

3-isopropylmalate dehydratase; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B; Belongs to the LeuD family. LeuD ty [...]