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| | AMD17742.1 | PhoU family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa) |
| | AMD18402.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (6176 aa) |
| | AMD16558.1 | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa) |
| | albA | DNA/RNA-binding protein albA; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (91 aa) |
| | AMD16579.1 | Cell division control protein Cdc6; Involved in regulation of DNA replication. (387 aa) |
| | polB | DNA polymerase II; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (556 aa) |
| | AMD16604.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa) |
| | AMD16612.1 | Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa) |
| | AMD18405.1 | Replication protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (311 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1077 aa) |
| | AMD16644.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | AMD16666.1 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa) |
| | AMD16668.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa) |
| | AMD16670.1 | DNA-directed RNA polymerase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa) |
| | csl4 | RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa) |
| | srp54 | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (449 aa) |
| | pus10 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (401 aa) |
| | AMD16679.1 | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa) |
| | rsmA | 16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (290 aa) |
| | polC | DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1099 aa) |
| | lysS | lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa) |
| | AMD16732.1 | tRNA CCA-pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa) |
| | AMD16741.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa) |
| | fen | Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa) |
| | tbp | Transcription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (718 aa) |
| | AMD16764.1 | Ribosome assembly protein YhbY; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa) |
| | AMD16765.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PDCD5 family. (118 aa) |
| | eif6 | Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa) |
| | rpl18a | 50S ribosomal protein LX; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa) |
| | AMD16777.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | AMD16810.1 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | lig | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (552 aa) |
| | AMD16814.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa) |
| | AMD16823.1 | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | tfe | Transcription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (172 aa) |
| | spt5 | Antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (156 aa) |
| | rpl11 | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (160 aa) |
| | rpl1 | 50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rplP0 | Acidic ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (899 aa) |
| | thiI | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (384 aa) |
| | AMD16845.1 | Translation factor Sua5; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa) |
| | radB | DNA repair protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (234 aa) |
| | ef1B | Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | AMD16875.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (579 aa) |
| | AMD16877.1 | DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (749 aa) |
| | AMD16878.1 | Type III restriction enzyme, res subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (895 aa) |
| | AMD16897.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa) |
| | AMD16912.1 | PhoU family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa) |
| | AMD16929.1 | ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | mutS2 | DNA mismatch repair protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (641 aa) |
| | eif2b | Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa) |
| | AMD16952.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MCM family. (668 aa) |
| | AMD16959.1 | ATP-dependent helicase; Hel112; monomeric form of the enzyme from Sulfolobus shows 3'-5' ATP-dependent helicase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa) |
| | nucS | Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (260 aa) |
| | AMD16977.1 | Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa) |
| | AMD16997.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (158 aa) |
| | AMD17004.1 | tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | AMD17012.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa) |
| | dnaG | Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (414 aa) |
| | AMD17041.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa) |
| | AMD17065.1 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | nac | Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (116 aa) |
| | AMD17100.1 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa) |
| | AMD17113.1 | Nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (154 aa) |
| | AMD17121.1 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | AMD17124.1 | DNA modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa) |
| | AMD17148.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
| | AMD17182.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa) |
| | AMD17192.1 | Exosome protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa) |
| | AMD17206.1 | AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (654 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa) |
| | AMD17236.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (863 aa) |
| | AMD17252.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa) |
| | rpl37ae | 50S ribosomal protein L37; Binds to the 23S rRNA. (89 aa) |
| | AMD17268.1 | Ribonucleotide-diphosphate reductase subunit beta; Probably involved in the biogenesis of the ribosome. (161 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (583 aa) |
| | AMD17281.1 | Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | AMD17292.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa) |
| | AMD17307.1 | DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | AMD17334.1 | DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa) |
| | AMD17346.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa) |
| | AMD17365.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1002 aa) |
| | AMD17386.1 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa) |
| | AMD17389.1 | Adenine nucleotide alpha hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | AMD17413.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (331 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa) |
| | AMD17472.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa) |
| | cca | tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa) |
| | AMD17502.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (663 aa) |
| | AMD17539.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa) |
| | AMD17564.1 | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa) |
| | AMD17586.1 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa) |
| | AMD17588.1 | Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | rpl37e | 50S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa) |
| | AMD17592.1 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the snRNP Sm proteins family. (76 aa) |
| | AMD17593.1 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa) |
| | AMD17621.1 | DNA-directed RNA polymerase subunit E; Participates in both the initiation and recycling phases of transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa) |
| | eif2g | Translation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (404 aa) |
| | infB | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (596 aa) |
| | rpl24e | 50S ribosomal protein L24; Binds to the 23S rRNA. (53 aa) |
| | rpl7ae | 50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (122 aa) |
| | AMD17630.1 | Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa) |
| | AMD17634.1 | Ribonuclease BN; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa) |
| | AMD17635.1 | DtxR family iron (metal) dependent repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa) |
| | rrp4 | RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (306 aa) |
| | AMD17661.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | AMD17665.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (753 aa) |
| | AMD17671.1 | XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa) |
| | AMD17697.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa) |
| | thiI-2 | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (383 aa) |
| | AMD18461.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa) |
| | tgtA | 7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (659 aa) |
| | srp19 | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (89 aa) |
| | AMD17773.1 | Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa) |
| | AMD18464.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa) |
| | AMD17776.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa) |
| | AMD17784.1 | DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa) |
| | AMD17786.1 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (514 aa) |
| | AMD17827.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa) |
| | rnj | Ribonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | AMD17840.1 | DNA-directed RNA polymerase subunit N; Derived by automated computational analysis using gene prediction method: Protein Homology. (56 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa) |
| | rps11 | 30S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rps4 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (179 aa) |
| | rps13 | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa) |
| | truB | H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (321 aa) |
| | rpl15 | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa) |
| | rps5 | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (213 aa) |
| | rpl18 | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa) |
| | rpl19e | 50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa) |
| | rpl6 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) |
| | rps8 | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl5 | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (170 aa) |
| | rps4e | 30S ribosomal protein S4e; The function of this ribosomal subunit is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa) |
| | rpl24p | 50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa) |
| | rpl14 | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rps17 | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa) |
| | rnp1 | Ribonuclease P protein component 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (92 aa) |
| | AMD17871.1 | Translation initiation factor Sui1; In yeast this protein is involved in start site selection during the initiation of translation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUI1 family. (112 aa) |
| | rps3 | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (252 aa) |
| | rpl22 | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa) |
| | rps19p | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl2p | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa) |
| | rpl23 | 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4lp | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (254 aa) |
| | rpl3 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa) |
| | AMD17890.1 | Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (668 aa) |
| | AMD17933.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa) |
| | AMD17950.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa) |
| | AMD17953.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa) |
| | AMD17957.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa) |
| | truA | Pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (289 aa) |
| | AMD18002.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa) |
| | AMD18019.1 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa) |
| | AMD18472.1 | Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology. (944 aa) |
| | AMD18025.1 | DNA adenine methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa) |
| | AMD18027.1 | Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa) |
| | AMD18054.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa) |
| | eif5a | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (132 aa) |
| | prf1 | Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (414 aa) |
| | rps10p | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa) |
| | fusA | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (732 aa) |
| | rps7 | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (186 aa) |
| | rps12 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa) |
| | nusA | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (143 aa) |
| | rpl30e | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (397 aa) |
| | AMD18094.1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (921 aa) |
| | AMD18095.1 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (601 aa) |
| | AMD18096.1 | DNA-directed RNA polymerase subunit B'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (77 aa) |
| | AMD18135.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa) |
| | eif1a | Translation initiation factor IF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (101 aa) |
| | AMD18146.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa) |
| | AMD18148.1 | Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa) |
| | top6B | DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (567 aa) |
| | top6A | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (364 aa) |
| | AMD18151.1 | Metal-sensitive transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa) |
| | AMD18154.1 | Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (204 aa) |
| | AMD18209.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | trm1 | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (390 aa) |
| | AMD18213.1 | AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa) |
| | AMD18219.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa) |
| | AMD18222.1 | DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa) |
| | AMD18227.1 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa) |
| | flpA | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (213 aa) |
| | sfsA | Sugar fermentation stimulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. (248 aa) |
| | hjc | Holliday junction resolvase; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (135 aa) |
| | AMD18486.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa) |
| | AMD18277.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (746 aa) |
| | nop10 | Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (55 aa) |
| | eif2a | Translation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (266 aa) |
| | rpl44e | 50S ribosomal protein L44; Binds to the 23S rRNA. (92 aa) |
| | pcn | DNA polymerase; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. (244 aa) |
| | AMD18312.1 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa) |
| | truD | Pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (418 aa) |
| | rfc | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa) |
| | AMD18346.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa) |
| | AMD18348.1 | Hef nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa) |
| | AMD18352.1 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (608 aa) |
| | AMD18376.1 | Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | AMD18499.1 | LSM domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa) |
| | aspC | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
