STRINGSTRING
AMD16564.1 AMD16564.1 AMD16569.1 AMD16569.1 AMD16571.1 AMD16571.1 pyrB pyrB AMD16585.1 AMD16585.1 AMD16611.1 AMD16611.1 AMD16615.1 AMD16615.1 thiC thiC AMD16738.1 AMD16738.1 AMD17482.1 AMD17482.1 AMD17490.1 AMD17490.1 AMD17496.1 AMD17496.1 AMD17498.1 AMD17498.1 AMD17538.1 AMD17538.1 AMD17555.1 AMD17555.1 pyrG pyrG AMD17580.1 AMD17580.1 AMD17593.1 AMD17593.1 AMD17613.1 AMD17613.1 rpiA rpiA AMD17690.1 AMD17690.1 AMD18460.1 AMD18460.1 purC purC AMD17762.1 AMD17762.1 AMD17770.1 AMD17770.1 AMD17789.1 AMD17789.1 aroC aroC AMD17823.1 AMD17823.1 AMD17833.1 AMD17833.1 eno eno rpl19e rpl19e AMD17931.1 AMD17931.1 AMD17944.1 AMD17944.1 AMD17987.1 AMD17987.1 AMD16744.1 AMD16744.1 ilvD ilvD purD purD ilvC ilvC fae-hps fae-hps AMD18347.1 AMD18347.1 AMD18313.1 AMD18313.1 trpD trpD trpA trpA AMD18210.1 AMD18210.1 AMD18209.1 AMD18209.1 top6B top6B AMD18133.1 AMD18133.1 AMD18132.1 AMD18132.1 AMD18130.1 AMD18130.1 AMD18105.1 AMD18105.1 thiM thiM rpl30e rpl30e AMD18075.1 AMD18075.1 AMD17996.1 AMD17996.1 AMD17993.1 AMD17993.1 AMD16765.1 AMD16765.1 eif6 eif6 AMD16783.1 AMD16783.1 AMD16795.1 AMD16795.1 glmM glmM AMD16809.1 AMD16809.1 thiC-2 thiC-2 ef1B ef1B AMD16914.1 AMD16914.1 AMD16922.1 AMD16922.1 AMD16928.1 AMD16928.1 AMD16929.1 AMD16929.1 eif2b eif2b AMD17016.1 AMD17016.1 dcd dcd AMD17065.1 AMD17065.1 AMD17080.1 AMD17080.1 AMD17088.1 AMD17088.1 AMD17109.1 AMD17109.1 AMD17115.1 AMD17115.1 guaAB guaAB cobQ cobQ AMD17246.1 AMD17246.1 pyrF pyrF AMD17298.1 AMD17298.1 AMD17315.1 AMD17315.1 AMD17316.1 AMD17316.1 AMD17352.1 AMD17352.1 AMD17405.1 AMD17405.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMD16564.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AMD16569.1Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AMD16571.13,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (227 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AMD16585.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AMD16611.1Spore coat protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
AMD16615.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (186 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (432 aa)
AMD16738.1Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
AMD17482.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (325 aa)
AMD17490.12'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (185 aa)
AMD17496.1Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
AMD17498.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
AMD17538.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
AMD17555.1Molybdenum cofactor biosynthesis protein MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa)
AMD17580.1Asparagine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AMD17593.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
AMD17613.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa)
AMD17690.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AMD18460.1Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (242 aa)
AMD17762.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AMD17770.1Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
AMD17789.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (333 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa)
AMD17823.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AMD17833.1Amino acid kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (266 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa)
rpl19e50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa)
AMD17931.1Molybdopterin adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
AMD17944.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (406 aa)
AMD17987.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
AMD16744.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (549 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (436 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
fae-hpsBifunctional formaldehyde-activating protein/3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (413 aa)
AMD18347.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AMD18313.1Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (449 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa)
AMD18210.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AMD18209.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
top6BDNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (567 aa)
AMD18133.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
AMD18132.1Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (234 aa)
AMD18130.1Acetylneuraminic acid synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
AMD18105.12-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (288 aa)
rpl30e50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa)
AMD18075.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
AMD17996.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
AMD17993.1Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AMD16765.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PDCD5 family. (118 aa)
eif6Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa)
AMD16783.1Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
AMD16795.15'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. (251 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
AMD16809.1Phosphoglucomutase; Catalyzes the interconversion of alpha-D-mannose 1-phosphate to alpha-D-mannose 6-phosphate and alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphohexose mutase family. (454 aa)
thiC-2Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
ef1BElongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa)
AMD16914.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AMD16922.12-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AMD16928.1Von Willebrand factor A; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AMD16929.1ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
eif2bTranslation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa)
AMD17016.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (194 aa)
AMD17065.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AMD17080.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
AMD17088.12-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AMD17109.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AMD17115.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
guaABGMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP. (308 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (508 aa)
AMD17246.1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (215 aa)
AMD17298.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMD17315.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
AMD17316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
AMD17352.1Nucleotide pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
AMD17405.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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