node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMD16783.1 | AMD17330.1 | TL18_01235 | TL18_04400 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.932 |
AMD16783.1 | dcd | TL18_01235 | TL18_02905 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.926 |
AMD16783.1 | ndk | TL18_01235 | TL18_06095 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.930 |
AMD16783.1 | pyrE | TL18_01235 | TL18_07775 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.418 |
AMD16783.1 | tmk | TL18_01235 | TL18_02260 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.936 |
AMD17330.1 | AMD16783.1 | TL18_04400 | TL18_01235 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.932 |
AMD17330.1 | dcd | TL18_04400 | TL18_02905 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.661 |
AMD17330.1 | pyrD | TL18_04400 | TL18_09465 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.466 |
AMD17330.1 | pyrE | TL18_04400 | TL18_07775 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.541 |
AMD17330.1 | pyrF | TL18_04400 | TL18_03990 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.449 |
AMD17330.1 | pyrG | TL18_04400 | TL18_05775 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.543 |
AMD17330.1 | pyrH | TL18_04400 | TL18_02825 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.489 |
AMD17330.1 | tmk | TL18_04400 | TL18_02260 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
AMD17330.1 | upp | TL18_04400 | TL18_03545 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.483 |
AMD18064.1 | AMD18224.1 | TL18_08550 | TL18_09460 | Orotate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AMD18064.1 | pyrD | TL18_08550 | TL18_09465 | Orotate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.908 |
AMD18064.1 | pyrE | TL18_08550 | TL18_07775 | Orotate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.915 |
AMD18064.1 | pyrF | TL18_08550 | TL18_03990 | Orotate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.929 |
AMD18224.1 | AMD18064.1 | TL18_09460 | TL18_08550 | Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
AMD18224.1 | carA | TL18_09460 | TL18_02395 | Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |